- ►shouxi.net EM Allister, NM Borradaile, JY Edwards, MW … - Diabetes, 2005 - Am Diabetes Assoc Microsomal triglyceride transfer protein (MTP) is necessary for hepatocyte
assembly and secretion of apolipoprotein (apo)B100-containing lipoproteins. The
citrus flavonoid naringenin, like insulin, decreased MTP expression in ... Cited by 33 - Related articles - All 5 versions
AWSKHF Lin - Diabetes, 2003 - 万方数据资源系统 Microsomal triglyceride transfer protein (MTP) is rate limiting for the assembly
and secretion of apolipoprotein B-containing lipoproteins. Elevated hepatic MTP
mRNA level, presumably as a result of impaired insulin signaling, has been ... Cited by 54 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org NM Borradaile, LE de Dreu, MW Huff - Diabetes, 2003 - Am Diabetes Assoc The flavonoid naringenin improves hyperlipidemia and hyperglycemia in
streptozotocin-treated rats. In HepG2 human hepatoma cells, naringenin inhibits
apolipoprotein B (apoB) secretion primarily by inhibiting microsomal ... Cited by 37 - Related articles - BL Direct - All 5 versions
CS Au, A Wagner, T Chong, W Qiu, JD Sparks, … - Metabolism, 2004 - Elsevier Insulin is known to be a downregulator of apolipoprotein B (apoB) via the
phosphatidylinositol 3-kinase (PI3K) pathway. Akt, also known as protein kinase
B (PKB), is a serine/threonine kinase downstream target of PI3K. Recent ... Cited by 30 - Related articles - All 10 versions
- ►ahajournals.org [PDF] J Tsai, W Qiu, R Kohen-Avramoglu, K Adeli - Arteriosclerosis, thrombosis, and vascular biology, 2007 - Am Heart Assoc Kluwer Health, 351 West Camden Street, Baltimore, MD 21202-2436. Phone:
410-528-4050. Permissions: Permissions & Rights Desk, Lippincott Williams &
Wilkins, a division of Wolters ... MEK–ERK Inhibition Corrects the ... Cited by 24 - Related articles - All 5 versions
- ►ahajournals.org AM Brown, GF Gibbons - Arteriosclerosis, thrombosis, and vascular biology, 2001 - Am Heart Assoc Abstract—— LY 294002 (80 µmol/L), an inhibitor of phosphoinositide
3-kinase, was used to investigate the involvement of this enzyme in the
insulin-mediated regulation of very low density lipoprotein (VLDL) ... Cited by 46 - Related articles - BL Direct - All 6 versions
NM Borradaile, LE de Dreu, PHR Barrett, CD … - Biochemistry, 2003 - pubs.acs.org Naringenin, the principal flavonoid in grapefruit, reduces plasma lipids in vivo
and inhibits apoB secretion, cholesterol esterification, and MTP activity in
HepG2 human hepatoma cells. Although naringenin inhibits ACAT, we recently ... Cited by 41 - Related articles - BL Direct - All 6 versions
- ►jlr.org NM Borradaile, LE de Dreu, PHR Barrett, MW … - The Journal of Lipid Research, 2002 - ASBMB The grapefruit flavonoid, naringenin, is hypocholesterolemic in vivo, and
inhibits basal apolipoprotein B (apoB) secretion and the expression and
activities of both ACAT and microsomal triglyceride transfer protein (MTP) ... Cited by 25 - Related articles - BL Direct - All 4 versions
- ►nih.gov [PDF] JD Sparks, TL Phung, M Bolognino, CE … - Biochemical Journal, 1996 - pubmedcentral.nih.gov Insulin inhibition of the secretion of apolipoprotein B (apo B) was studied in
primary cultures of rat hepatocytes by using brefeldin A (BFA), an inhibitor of
protein transport from the endoplasmic reticulum (ER) to the Golgi ... Cited by 67 - Related articles - BL Direct - All 6 versions
