- ►diabetesjournals.org AB Strawbridge, JS Elmendorf - Diabetes, 2005 - Am Diabetes Assoc Phosphatidylinositol (PI) 4,5-bisphosphate (PIP 2 ) plays a pivotal role in
insulin-stimulated glucose transport as an important precursor to PI
3,4,5-trisphosphate (PIP 3 ) and a key regulator of actin polymerization. ... Cited by 26 - Related articles - All 6 versions
AB Strawbridge, JS Elmendorf - Journal of cellular biochemistry, 2006 - pubmedcentral.nih.gov Endothelin-1 (ET-1) disrupts insulin-regulated glucose transporter GLUT4
trafficking. Since the negative consequence of chronic ET-1 exposure appears to
be independent of signal disturbance along the insulin receptor substrate-1/ ... Cited by 15 - Related articles - BL Direct - All 5 versions
- ►jbc.org G Chen, P Raman, P Bhonagiri, AB … - Journal of Biological Chemistry, 2004 - ASBMB Muscle and fat cells develop insulin resistance when cultured under
hyperinsulinemic conditions for sustained periods. Recent data indicate that
early insulin signaling defects do not fully account for the loss of ... Cited by 26 - Related articles - BL Direct - All 7 versions
M Younsi, D Quilliot, N Al-Makdissy, I … - Metabolism, 2002 - Elsevier The complex mechanisms by which obesity predisposes to insulin resistance are
not clearly understood. According to a cell membrane hypothesis of insulin
resistance, the defects in insulin action could be related to changes in ... Cited by 19 - Related articles - BL Direct - All 4 versions
- ►endojournals.org SF Kralik, P Liu, BJ Leffler, JS Elmendorf - Endocrinology, 2002 - Endocrine Soc In addition to insulin, hyperosmolarity induces glucose transporter 4 (GLUT4)
translocation in 3T3-L1 adipocytes. However, in contrast to insulin this
stimulation is independent of PI3K/Akt. In this study we assessed whether ... Cited by 19 - Related articles - BL Direct - All 5 versions
- ►oxfordjournals.org RJ Irving, JP Noon, GCM Watt, DJ Webb, BR … - Qjm, 2001 - Oxford Univ Press Endothelin-1, released from the vascular endothelium after cleavage from big
endothelin-1, is a potent paracrine vasoconstrictor peptide. Small studies
suggest that circulating levels of endothelin-1 are elevated in subjects ... Cited by 23 - Related articles - BL Direct - All 4 versions
A Advani, SM Marshall, TH Thomas - European Journal of Clinical Investigation, 2004 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 7 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org JJ Wilkes, A Hevener, J Olefsky - Diabetes, 2003 - Am Diabetes Assoc We determined whether chronic endothelin-1 (ET-1) treatment could lead to in
vivo insulin resistance. Like insulin, ET-1 acutely stimulated glucose transport
in isolated soleus muscle strips of WKY rats. ET-1 pretreatment (1 h) ... Cited by 49 - Related articles - BL Direct - All 4 versions
- ►whitelabs.org [PDF] ZY Jiang, QL Zhou, A Chatterjee, EP Feener, … - DIABETES-NEW YORK-, 1999 - Am Diabetes Assoc Diminished insulin action in the vasculature may con- tribute to the development
of cardiovascular diseases in diabetes. We have studied insulin's effects on the
phosphatidylinositol (PI) 3-kinase pathway in arterial smooth muscle cells ... Cited by 87 - Related articles - BL Direct - All 7 versions
- ►nih.gov K Ishibashi, T Imamura, PM Sharma, J Huang, … - Journal of Clinical Investigation, 2001 - Am Soc Clin Investig We recently reported that insulin and endothelin-1 (ET-1) can stimulate GLUT4
translocation via the heterotrimeric G protein Gαq/11 and through
PI3-kinase–mediated pathways in 3T3-L1 adipocytes. Because both hormones ... Cited by 53 - Related articles - BL Direct - All 8 versions
