- ►diabetesjournals.org JM Cacicedo, S Benjachareowong, E Chou, … - Diabetes, 2005 - Am Diabetes Assoc Apoptosis of pericytes (PCs) is an early event in diabetic retinopathy. It is
generally thought to be a consequence of sustained hyperglycemia. In keeping
with this, long-term (>7 days) incubation of cultured PCs in a high-glucose ... Cited by 48 - Related articles - All 6 versions
N Beeharry, JA Chambers, IC Green - Apoptosis, 2004 - Springer We have previously shown that saturated fatty acids in- duce DNA damage and
cause apoptotic cell death in insulin-producing β-cells. Here we examine
further the effects of single or combined dietary fatty acids on RINm5F ... Cited by 22 - Related articles - BL Direct - All 4 versions
- ►physiology.org DLM Hickson-Bick, GC Sparagna, LM Buja, JB … - American Journal of Physiology- Heart and Circulatory …, 2002 - Am Physiological Soc The saturated fatty acid palmitate induces apoptosis in neonatal rat
cardiomyocytes. This apoptosis is associated with early mitochondrial release of
cytochrome c and a subsequent loss of mitochondrial membrane potential. ... Cited by 37 - Related articles - BL Direct - All 4 versions
A Manea, M Raicu, M Simionescu - Biology of the Cell, 2005 - biolcell.org Abbreviations used: Ang II, angiotensin II; AT1, Ang II-receptor antipeptide;
CMC, cardiomyocyte; DCF, 2´,7´-dichlorofluorescein; DMEM, Dulbecco's modified
Eagle's medium; DPI, diphenylene iodonium; F12, Ham's nutrient mixture F12; ... Cited by 17 - Related articles - Cached - All 8 versions
TA Miller, NK LeBrasseur, GM Cote, MP … - Biochemical and Biophysical Research …, 2005 - Elsevier The cytotoxicity of saturated fatty acids has been implicated in the
pathophysiology of cardiovascular disease, though their effects on cardiac
myocytes are incompletely understood. We examined the effects of palmitate ... Cited by 25 - Related articles - All 4 versions
D Dyntar, M Eppenberger-Eberhardt, K … - Diabetes, 2001 - Am Diabetes Assoc Several studies support the concept of a diabetic cardiomyopathy in the absence
of discernible coronary artery disease, although its mechanism remains poorly
understood. We investigated the role of glucose and palmitic acid on ... Cited by 83 - Related articles - BL Direct - All 8 versions
B Hufnagel, M Dworak, M Soufi, Z Mester, Y … - Atherosclerosis, 2005 - Elsevier Activity of serine/threonine protein phosphatase type 2C is known to be
stimulated by certain unsaturated fatty acids and this enzyme dephosphorylates
Bad, thus acting on apoptosis. This prompted us to investigate endothelial ... Cited by 30 - Related articles - All 14 versions
A Planavila, M Alegret, RM Sánchez, R … - Biochemical pharmacology, 2005 - Elsevier Although it is generally believed that thiazolidinediones ameliorate insulin
resistance by lowering circulating free fatty acids, direct effects of these
drugs in skeletal muscle may also contribute to their antidiabetic action. ... Cited by 14 - Related articles - All 3 versions
DJ Powell, S Turban, A Gray, E Hajduch, HS … - Biochemical Journal, 2004 - pubmedcentral.nih.gov Non-esterified fatty acids (NEFAs) have been implicated in the pathogenesis of
skeletal muscle insulin resistance that may develop, in part, as a consequence
of a direct inhibitory effect on early insulin signalling events. Here we ... Cited by 58 - Related articles - BL Direct - All 6 versions
