LM Watts, VP Manchem, TA Leedom, AL Rivard … - Diabetes, 2005 - Am Diabetes Assoc Glucocorticoids (GCs) increase hepatic gluconeogenesis and play an important
role in the regulation of hepatic glucose output. Whereas systemic GC inhibition
can alleviate hyperglycemia in rodents and humans, it results in adrenal ... Cited by 29 - Related articles - All 7 versions
Y Liang, MC Osborne, BP Monia, S Bhanot, … - Metabolism, 2005 - Elsevier Specific blockade of glucocorticoid receptor (GCCR) action in the liver without
affecting the hypothalamus-pituitary-adrenal axis could be a novel
pharmaceutical approach to treat type 2 diabetes. In the present study, we ... Cited by 10 - Related articles - All 11 versions
C Opherk, F Tronche, C Kellendonk, D … - Molecular Endocrinology, 2004 - Endocrine Soc Hepatic glucose production by gluconeogenesis is the main source of glucose
during fasting and contributes significantly to hyperglycemia in diabetes
mellitus. Accordingly, glucose metabolism is tightly controlled by a ... Cited by 44 - Related articles - BL Direct - All 5 versions
Y LEE, A VASSILAKOS, N FENG, H JIN, M … - International journal of oncology, 2006 - cat.inist.fr GTI-2501 is a 20-mer oligonucleotide that is complementary to a coding region in
the mRNA of Rl, the large subunit of ribonucleotide reductase(RNR). In vitro
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- ►endojournals.org Y Liu, C Yan, Y Wang, Y Nakagawa, N Nerio, … - Endocrinology, 2006 - Endocrine Soc The glucocorticoid receptor (GR) is a crucial target gene for
glucocorticoid-induced insulin resistance and hepatic gluconeogenesis linked to
the development of type 2 diabetes. The liver X receptors (LXRs) are ... Cited by 15 - Related articles - BL Direct - All 4 versions
R Basu, R Singh, A Basu, CM Johnson, RA … - Diabetes, 2006 - Am Diabetes Assoc The splanchnic bed produces cortisol at rates approximating extraadrenal tissues
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