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Scholar Results 1 - 10 of about 101 related to Basu: Obesity and type 2 diabetes impair insulin-induced suppression of glycogenolysis as.... (0.11 sec) 

Obesity and type 2 diabetes impair insulin-induced suppression of glycogenolysis as well …

- shouxi.net
R Basu, V Chandramouli, B Dicke, B Landau, … - Diabetes, 2005 - Am Diabetes Assoc
To determine whether the hepatic insulin resistance of obesity and type 2
diabetes is due to impaired insulin-induced suppression of glycogenolysis as
well as gluconeogenesis, 10 lean nondiabetic, 10 obese nondiabetic, and 11 ...
Cited by 25 - Related articles - All 5 versions

Higher insulin concentrations are required to suppress gluconeogenesis than …


A Adkins, R Basu, M Persson, B Dicke, P … - Diabetes, 2003 - Am Diabetes Assoc
To determine the mechanism(s) by which insulin inhibits endogenous glucose
production (EGP) in nondiabetic humans, insulin was infused at rates of 0.25,
0.375, or 0.5 mU · kg −1 · min −1 and glucose was clamped at ∼5.5 ...
Cited by 30 - Related articles - BL Direct - All 4 versions

Changes in hepatic glycogen cycling during a glucose load in healthy humans


H Stingl, V Chandramouli, WC Schumann, A … - Diabetologia, 2006 - Springer
Abstract Aims/hypothesis: Glycogen cycling, ie simul- taneous glycogen synthesis
and glycogenolysis, affects estimates of glucose fluxes using tracer techniques
and may contribute to hyperglycaemia in diabetic conditions. This study ...
Cited by 12 - Related articles - BL Direct - All 4 versions

Determination of the enrichment of the hydrogen bound to carbon 5 of glucose on 2H2O …


WC Schumann, A Gastaldelli, V Chandramouli, … - Analytical Biochemistry, 2001 - Elsevier
4. M. Roden, H. Stingl, V. Chandramouli, WC Schumann, A. Hofer, BR Landau, P.
Nowotny, W. Waldhausl and GI Shulman, Effects of free fatty acids elevation on
postabsorptive endogenous glucose production and gluconeogenesis in man. ...
Cited by 30 - Related articles - BL Direct - All 3 versions

Gluconeogenesis in moderately and severely hyperglycemic patients with type 2 diabetes …

- physiology.org
G Boden, X Chen, TP Stein - American Journal of Physiology- Endocrinology And …, 2001 - Am Physiological Soc
We tested the generally accepted concept that increased gluconeogenesis (GNG)
and endogenous glucose production (EGP) are the main reasons for postabsorptive
hyperglycemia in patients with type 2 diabetes mellitus (T2DM). GNG was ...
Cited by 76 - Related articles - BL Direct - All 3 versions

Analysis of gluconeogenic pathways in vivo by distribution of 2H in plasma glucose: …


SC Burgess, M Nuss, V Chandramouli, DS … - Analytical biochemistry, 2003 - Elsevier
Glucose metabolism is tightly regulated under normal physiological conditions
because a minimum concentration in plasma is required for normal brain [1] and
erythrocyte function [2]. However, among patients with common disorders, ...
Cited by 27 - Related articles - All 4 versions

Both fasting glucose production and disappearance are abnormal in people with" mild" and" …

- physiology.org
R Basu, WF Schwenk, RA Rizza - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc
To determine whether regulation of fasting endogenous glucose production (EGP)
and glucose disappearance (R d ) are both abnormal in people with type 2
diabetes, EGP and R d were measured in 7 "severe" (SD), 9 "mild" (MD), and ...
Cited by 28 - Related articles - All 3 versions

Quantitation of gluconeogenesis by 2H nuclear magnetic resonance analysis of plasma …

- uc.pt [PDF] 
JG Jones, RA Carvalho, AD Sherry, CR … - Analytical Biochemistry, 2000 - Elsevier
We present a simple 2 H NMR assay of the fractional contribution of
gluconeogenesis to hepatic glucose output following ingestion of 2 H 2 O. The
assay is based on the measurement of relative deuterium enrichment in ...
Cited by 21 - Related articles - BL Direct - All 5 versions

Inhibition of fructose 1, 6-bisphosphatase reduces excessive endogenous glucose production …

- shouxi.net
PD van Poelje, SC Potter, VC Chandramouli, … - Diabetes, 2006 - Am Diabetes Assoc
Gluconeogenesis is increased in type 2 diabetes and contributes significantly to
fasting and postprandial hyperglycemia. We recently reported the discovery of
the first potent and selective inhibitors of fructose 1,6-bisphosphatase ...
Cited by 16 - Related articles - BL Direct - All 5 versions

Effects of nonglucose nutrients on insulin secretion and action in people with pre-diabetes

- diabetesjournals.org
G Bock, C Dalla Man, M Campioni, E … - Diabetes, 2007 - Am Diabetes Assoc
To determine whether nonglucose nutrient–induced insulin secretion is impaired
in pre-diabetes, subjects with impaired or normal fasting glucose were studied
after ingesting either a mixed meal containing 75 g glucose or 75 g glucose ...
Cited by 6 - Related articles - BL Direct - All 5 versions


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