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Scholar Results 1 - 10 of about 101 related to Rahmouni: Role of selective leptin resistance in diet-induced obesity hypertension. (0.09 sec) 

Role of selective leptin resistance in diet-induced obesity hypertension

- shouxi.net
K Rahmouni, DA Morgan, GM Morgan, AL … - Diabetes, 2005 - Am Diabetes Assoc
Leptin is an adipocyte-derived hormone that plays a key role in the regulation
of body weight through its actions on appetite and metabolism. Leptin also
increases sympathetic nerve activity (SNA) and blood pressure. We tested ...
Cited by 95 - Related articles - All 6 versions

The concept of selective leptin resistance


MLG Correia, WG Haynes, K Rahmouni, DA … - Diabetes, 2002 - Am Diabetes Assoc
Leptin, a hormone secreted by adipose tissue, acts to inhibit appetite and
promote metabolism, thereby reducing body weight. Leptin also increases
sympathetic activity and arterial pressure. Several murine models of ...
Cited by 108 - Related articles - BL Direct - All 4 versions

Cardiovascular responses evoked by leptin acting on neurons in the ventromedial and …

- ahajournals.org
AJ Marsh, MAP Fontes, S Killinger, DB … - Hypertension, 2003 - Am Heart Assoc
Leptin, a circulating hormone produced by adipose tissue, is believed to act on
the hypothalamus to increase sympathetic vasomotor activity, in addition to its
well-known effects on appetite and energy expenditure. In this study, we ...
Cited by 45 - Related articles - BL Direct - All 6 versions

Contrasting blood pressure effects of obesity in leptin-deficient ob/ob mice and agouti …


AL Mark, RA Shaffer, MLG Correia, DA … - Journal of hypertension, 1999 - journals.lww.com
Objective Recent advances in understanding the neuroendocrine pathways
regulating appetite, metabolism and body weight afford an opportunity to explore
further the mechanisms by which obesity in¯uences arterial pressure. ob/ob( ...
Cited by 138 - Related articles - BL Direct - All 3 versions

Chronic cardiovascular and renal actions of leptin: role of adrenergic activity

- ahajournals.org
M Carlyle, OB Jones, JJ Kuo, JE Hall - Hypertension, 2002 - Am Heart Assoc
Abstract— This study was designed to determine the role of changes in
adrenergic activity in mediating the chronic cardiovascular, renal, and
metabolic actions of leptin. Male Sprague-Dawley rats were implanted with ...
Cited by 125 - Related articles - BL Direct - All 4 versions

Leptin acts in the central nervous system to produce dose-dependent changes in arterial …

- ahajournals.org
MLG Correia, DA Morgan, WI Sivitz, AL Mark … - Hypertension, 2001 - Am Heart Assoc
Systemic leptin increases energy expenditure through sympathetic mechanisms,
decreases appetite, and increases arterial pressure. We tested the hypothesis
that the pressor action of leptin is mediated by the central nervous ...
Cited by 97 - Related articles - BL Direct - All 5 versions

Selective resistance to central neural administration of leptin in agouti obese mice

- ahajournals.org
K Rahmouni, WG Haynes, DA Morgan, AL … - Hypertension, 2002 - Am Heart Assoc
Animals We studied 13- to 16-week-old male agouti yellow obese mice (C57BL/6J-A
y ) and their wild-type controls C57BL/6J a/a (Jackson Laboratories). Animals
were housed in a temperature-, humidity-, and light-controlled room ...
Cited by 67 - Related articles - BL Direct - All 7 versions

Leptin and the cardiovascular system

- leptinresearch.org [PDF] 
K Rahmouni, WG Haynes - Recent progress in hormone research, 2004 - Endocrine Soc
Obesity is associated with increased cardiovascular morbidity and mortality, in
part through development of hypertension. Recent observations suggest that the
cardiovascular actions of leptin may help explain the link between excess ...
Cited by 54 - Related articles - BL Direct - All 5 versions

Direct effects of leptin on size and extracellular matrix components of human pediatric …

- cardiovascres.org
S Madani, S De Girolamo, DM Munoz, RK Li, … - Cardiovascular research, 2006 - cardiovascres.org
Results: We show using gelatin zymography that leptin dose-dependently (0–60
nM) increased proteolytic activity at ~72 kDa. Accordingly, upon quantitative
PCR analysis we found that leptin increased expression of matrix ...
Cited by 22 - Related articles - All 7 versions

Regional haemodynamic effects of recombinant murine or human leptin in conscious rats


SM Gardiner, PA Kemp, JE March, T Bennett - British journal of pharmacology, 2000 - pubmedcentral.nih.gov
Regional haemodynamic responses to recombinant murine or human leptin were
assessed in conscious, chronically-instrumented, male, Long-Evans rats
(350–450 g). ... Human, but not murine, leptin caused a slight ...
Cited by 27 - Related articles - BL Direct - All 4 versions


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