- ►shouxi.net K Rahmouni, DA Morgan, GM Morgan, AL … - Diabetes, 2005 - Am Diabetes Assoc Leptin is an adipocyte-derived hormone that plays a key role in the regulation
of body weight through its actions on appetite and metabolism. Leptin also
increases sympathetic nerve activity (SNA) and blood pressure. We tested ... Cited by 95 - Related articles - All 6 versions
MLG Correia, WG Haynes, K Rahmouni, DA … - Diabetes, 2002 - Am Diabetes Assoc Leptin, a hormone secreted by adipose tissue, acts to inhibit appetite and
promote metabolism, thereby reducing body weight. Leptin also increases
sympathetic activity and arterial pressure. Several murine models of ... Cited by 108 - Related articles - BL Direct - All 4 versions
- ►ahajournals.org AJ Marsh, MAP Fontes, S Killinger, DB … - Hypertension, 2003 - Am Heart Assoc Leptin, a circulating hormone produced by adipose tissue, is believed to act on
the hypothalamus to increase sympathetic vasomotor activity, in addition to its
well-known effects on appetite and energy expenditure. In this study, we ... Cited by 45 - Related articles - BL Direct - All 6 versions
AL Mark, RA Shaffer, MLG Correia, DA … - Journal of hypertension, 1999 - journals.lww.com Objective Recent advances in understanding the neuroendocrine pathways
regulating appetite, metabolism and body weight afford an opportunity to explore
further the mechanisms by which obesity in¯uences arterial pressure. ob/ob( ... Cited by 138 - Related articles - BL Direct - All 3 versions
- ►ahajournals.org M Carlyle, OB Jones, JJ Kuo, JE Hall - Hypertension, 2002 - Am Heart Assoc Abstract— This study was designed to determine the role of changes in
adrenergic activity in mediating the chronic cardiovascular, renal, and
metabolic actions of leptin. Male Sprague-Dawley rats were implanted with ... Cited by 125 - Related articles - BL Direct - All 4 versions
- ►ahajournals.org MLG Correia, DA Morgan, WI Sivitz, AL Mark … - Hypertension, 2001 - Am Heart Assoc Systemic leptin increases energy expenditure through sympathetic mechanisms,
decreases appetite, and increases arterial pressure. We tested the hypothesis
that the pressor action of leptin is mediated by the central nervous ... Cited by 97 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org K Rahmouni, WG Haynes, DA Morgan, AL … - Hypertension, 2002 - Am Heart Assoc Animals We studied 13- to 16-week-old male agouti yellow obese mice (C57BL/6J-A
y ) and their wild-type controls C57BL/6J a/a (Jackson Laboratories). Animals
were housed in a temperature-, humidity-, and light-controlled room ... Cited by 67 - Related articles - BL Direct - All 7 versions
- ►leptinresearch.org [PDF] K Rahmouni, WG Haynes - Recent progress in hormone research, 2004 - Endocrine Soc Obesity is associated with increased cardiovascular morbidity and mortality, in
part through development of hypertension. Recent observations suggest that the
cardiovascular actions of leptin may help explain the link between excess ... Cited by 54 - Related articles - BL Direct - All 5 versions
- ►cardiovascres.org S Madani, S De Girolamo, DM Munoz, RK Li, … - Cardiovascular research, 2006 - cardiovascres.org Results: We show using gelatin zymography that leptin dose-dependently (0–60
nM) increased proteolytic activity at ~72 kDa. Accordingly, upon quantitative
PCR analysis we found that leptin increased expression of matrix ... Cited by 22 - Related articles - All 7 versions
SM Gardiner, PA Kemp, JE March, T Bennett - British journal of pharmacology, 2000 - pubmedcentral.nih.gov Regional haemodynamic responses to recombinant murine or human leptin were
assessed in conscious, chronically-instrumented, male, Long-Evans rats
(350–450 g). ... Human, but not murine, leptin caused a slight ... Cited by 27 - Related articles - BL Direct - All 4 versions