MJ Riedel, PE Light - Diabetes, 2005 - Am Diabetes Assoc Metabolic regulation of pancreatic β-cell ATP-sensitive K + channel (K ATP channel) function
plays a key role in the process of glucose-stimulated insulin secretion (GSIS). Modulation of K
ATP channel activity by long-chain acyl CoAs represents an important endogenous ... Cited by 20 - Related articles - All 7 versions
- ►hivinfosource.org [PDF] MJ Riedel, P Boora, D Steckley, G de Vries, PE Light - Diabetes, 2003 - Am Diabetes Assoc The commonly occurring E23K and I337V Kir6.2 polymorphisms in the ATP-sensitive potassium
(K ATP ) channel are more frequent in Caucasian type 2 diabetic populations. However, the underlying
cellular mechanisms contributing to the pathogenesis of type 2 diabetes remain ... Cited by 51 - Related articles - BL Direct - All 25 versions
- ►endojournals.org M Fox, E Jocelyn, CG Nichols, PE Light - Molecular Endocrinology, 2004 - Endocrine Soc ATP-sensitive potassium (K ATP ) channels are crucial to pancreatic endocrine function and
their activation by acyl coenzyme A esters (acyl CoAs) may disrupt hormone secretion, contributing
to the pathophysiology of type 2 diabetes. The molecular mechanism of this activation is ... Cited by 19 - Related articles - BL Direct - All 3 versions
RM Van Dam, B Hoebee, JC Seidell, MM Schaap, … - Diabet Med, 2005 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 43 - Related articles - All 4 versions
JEM Fox, J Magga, WR Giles, PE Light - Metabolism, 2003 - Elsevier Recent evidence demonstrates that long-chain acyl coenzyme A esters (CoAs) activate cardiac
and β-cell plasma-membrane (pmK ATP ) adenosine triphosphate (ATP)-sensitive potassium
channels. In this study, we have investigated the differential effects of acyl CoAs of short ... Cited by 11 - Related articles - All 10 versions
MJ Riedel, I Baczkó, GJ Searle, N Webster, M … - The EMBO …, 2006 - pubmedcentral.nih.gov The sodium–calcium exchanger (NCX) is a critical mediator of calcium homeostasis. In the
heart, NCX1 predominantly operates in forward mode to extrude Ca 2+ ; however, reverse-mode
NCX1 activity during ischemia/reperfusion (IR) contributes to Ca 2+ loading and electrical ... Cited by 11 - Related articles - BL Direct - All 8 versions
D Schulze, M Rapedius, T Krauter, T … - The Journal of …, 2003 - Physiological Soc Phosphatidylinositol phosphates (PIPs, eg PIP 2 ) and long-chain acyl-CoA esters (eg
oleoyl-CoA) are potent activators of K atp channels that are thought to link K atp channel activity
to the cellular metabolism of PIPs and fatty acids. Here we show that the two types of lipid ... Cited by 44 - Related articles - BL Direct - All 7 versions
[CITATION] The prevalent Glu23Lys polymorphism in the potassium inward rectifier 6.2 (Kir6. 2 …
AJ Smith, TK Taneja, J Mankouri, A … - Expert Reviews in …, 2007 - Cambridge Univ Press ATP-sensitivepotassium(K ATP )channelsplayakeyroleintheregulationofinsulin secretion by coupling
glucose metabolism to the electrical activity of pancreatic b-cells. To generate an electric signal
of suitable magnitude, the plasma membrane of the b-cell must contain an appropriate ... Cited by 4 - Related articles - All 2 versions
