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Scholar Results 1 - 10 of about 101 related to Salehi: Inhibition of purinoceptors amplifies glucose-stimulated insulin release with removal.... (0.12 sec) 

Inhibition of purinoceptors amplifies glucose-stimulated insulin release with removal of its …


A Salehi, SS Qader, E Grapengiesser, B … - Diabetes, 2005 - Am Diabetes Assoc
External ATP has been proposed to be an autocrine regulator of
glucose-stimulated insulin secretion and responsible for the synchronization of
the Ca 2+ rhythmicity in the β-cells required for a pulsatile release of ...
Cited by 19 - Related articles - All 5 versions

Pulses of external ATP aid to the synchronization of pancreatic β-cells by generating …


E Grapengiesser, H Dansk, B Hellman - Biochemical pharmacology, 2004 - Elsevier
Pancreatic β-cells respond to glucose stimulation with increase of the
cytoplasmic Ca 2+ concentration ([Ca 2+ ] i ), manifested as membrane-derived
slow oscillations sometimes superimposed with transients of intracellular ...
Cited by 14 - Related articles - All 4 versions

Pancreatic {beta}-cells communicate via intermittent release of ATP

- physiology.org
B Hellman, H Dansk, E Grapengiesser - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc
The role of external ATP for intercellular communication was studied in
glucose-stimulated pancreatic -cells isolated from ob/ob mice. Digital image
analyses with fura-2 revealed spontaneous transients of cytoplasmic Ca 2+ ...
Cited by 35 - Related articles - BL Direct - All 4 versions

Glucose induces glucagon release pulses antisynchronous with insulin and sensitive to …

- endojournals.org
E Grapengiesser, A Salehi, SS Qader, B … - Endocrinology, 2006 - Endocrine Soc
Both increase of the glucose concentration and activation of purinoceptors are
known to affect pancreatic -cells. Effects obtained with various purino
derivatives at 2.8 and 8.3 mmol/liter glucose have been taken to indicate ...
Cited by 9 - Related articles - BL Direct - All 4 versions

Release of small transmitters through kiss-and-run fusion pores in rat pancreatic β cells

- cell.com
PE MacDonald, M Braun, J Galvanovskis, P … - Cell Metabolism, 2006 - Elsevier
Exocytosis of secretory vesicles begins with a fusion pore connecting the
vesicle lumen to the extracellular space. This pore may then expand or it may
close to recapture the vesicle intact. The contribution of the latter, ...
Cited by 21 - Related articles - All 8 versions

The ins and outs of secretion from pancreatic beta-cells: control of single-vesicle exo-and …


PE MacDonald, P Rorsman - Physiology (Bethesda, Md.), 2007 - ncbi.nlm.nih.gov
Exocytosis of insulin-containing secretory vesicles in pancreatic beta-cells is
crucial to maintenance of plasma glucose levels. They fuse with the plasma
membrane in a regulated manner to release their contents and are ...
Cited by 13 - Related articles - BL Direct - All 4 versions

The P2Y 1 receptor is involved in the maintenance of glucose homeostasis and in insulin …


C Léon, M Freund, O Latchoumanin, A Farret, … - Purinergic Signalling, 2005 - Springer
& Christian Gachet 1 1 Institut National de la Santé et de la Recherche
Médicale U.311, Etablissement Français du Sang-Alsace, Strasbourg Cedex,
France; 2 Centre de Pharmacologie et Biotechnologie pour la Santé, CNRS ...
Cited by 10 - Related articles - All 5 versions

Comparison of insulin and glucagon pulsatile secretion between the rat and dog pancreas in- …


J Stagner, E Samols - Life sciences, 1988 - ncbi.nlm.nih.gov
Sustained pulses of insulin and glucagon were obtained from the isolated
perfused in vitro rat pancreas. The respective periodicity of hormone release
(peak to peak interval) was calculated by the Pulsar computer algorithm as ...
Cited by 12 - Related articles

Multiple sites of purinergic control of insulin secretion in mouse pancreatic beta-cells

- diabetesjournals.org [PDF] 
CR Poulsen, K Bokvist, HL Olsen, M Hoy, K … - Diabetes, 1999 - Am Diabetes Assoc
In mouse pancreatic ß-cells, extracellular ATP (0.1 mmol/l) effectively reduced
glucose-induced insulin secretion. This inhibitory action resulted from a direct
interference with the secretory machinery, and AT P suppressed ...
Cited by 35 - Related articles - BL Direct - All 5 versions

P2X and P2Y purinoceptor expression in pancreas from streptozotocin-diabetic rats

- ucl.ac.uk [PDF] 
R Coutinho-Silva, M Parsons, T Robson, J … - Molecular and cellular endocrinology, 2003 - Elsevier
The expression of the nucleotide receptors P2X 1 , P2X 2 , P2X 7 , P2Y 1 , P2Y 2
and P2Y 4 , in the pancreas of the streptozotocin-induced diabetic rat was
investigated using immunohistochemistry. In diabetic animals, P2X 7 ...
Cited by 28 - Related articles - All 20 versions


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