- ►diabetesjournals.org T Lu, XL Wang, T He, W Zhou, TL Kaduce, ZS Katusic, … - Diabetes, 2005 - Am Diabetes Assoc We studied the arachidonic acid (AA)-mediated modulation of large-conductance Ca 2+ -activated
K + (BK) channels in coronary arterial smooth myocytes from lean control and Zucker Diabetic
Fatty (ZDF) rats. A total of 1 μmol/l AA enhanced BK current by 274% in lean and by 98% ... Cited by 22 - Related articles - All 5 versions
- ►physiology.org W Zhou, XL Wang, TL Kaduce, AA … - American Journal of …, 2005 - Am Physiological Soc Arachidonic acid (AA) is a precursor of important vasoactive metabolites, but the role of AA-mediated
vasodilation in Type 2 diabetes is not known. Using Zucker diabetic fatty (ZDF) rats, we examined
the effects of AA in small mesenteric arteries preconstricted with endothelin. In ZDF rat ... Cited by 19 - Related articles - BL Direct - All 4 versions
- ►physiology.org MP Burnham, IT Johnson, AH … - American Journal of …, 2006 - Am Physiological Soc Although it is well established that diabetes impairs endothelium-dependent vasodilation, including
those pathways involving vascular myocyte large-conductance Ca 2+ -activated K + channels
(BK Ca ), little is known about the effects of diabetes on BK Ca activation as an intrinsic ... Cited by 15 - Related articles - BL Direct - All 3 versions
- ►physiology.org C Dimitropoulou, G Han, AW Miller, M … - American Journal of …, 2002 - Am Physiological Soc Insulin resistance (IR) syndrome is associated with impaired vascular relaxation; however, the
underlying pathophysiology is unknown. Potassium channel activation causes vascular smooth
muscle hyperpolarization and relaxation. The present study determined whether a ... Cited by 31 - Related articles - BL Direct - All 4 versions
Y Tanaka, K Koike, L Toro - Journal of Smooth Muscle Research, 2004 - J-STAGE The endothelium of blood vessels plays a crucial role in the regulation of blood flow by controlling
mechanical functions of underlying vascular smooth muscle. The regulation by the endothelium
of vascular smooth muscle relaxation and contraction is mainly achieved via the release ... Cited by 35 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org MK McGahon, DP Dash, A Arora, N Wall, J … - Circulation …, 2007 - Am Heart Assoc Retinal vasoconstriction and reduced retinal blood flow precede the onset of diabetic
retinopathy. The pathophysiological mechanisms that underlie increased retinal arteriolar tone
during diabetes remain unclear. Normally, local Ca 2+ release events (Ca 2+ -sparks), ... Cited by 20 - Related articles - All 6 versions
- ►physiology.org AH Bubolz, H Li, Q Wu, Y Liu - American Journal of Physiology- …, 2005 - Am Physiological Soc We have shown that short-term exposure of rat small coronary arteries (RSCAs) to high glucose
enhances superoxide (O 2 – ·) formation and impairs cAMP-mediated dilation by reducing
voltage-gated K + (K v ) channel function. However, it is not clear whether the impairment ... Cited by 12 - Related articles - BL Direct - All 4 versions
- ►physiology.org [PDF] SA Kempson, JM Edwards, A Osborn, M … - American Journal of …, 2008 - Am Physiological Soc Page 1. F-00108-2008 Revision 1 Revised title: Acute inhibition of the betaine transporter by
ATP and adenosine in renal MDCK cells Stephen A Kempson, Jason M Edwards, Alyssa Osborn,
& Michael Sturek Department of Cellular & Integrative Physiology ... Cited by 2 - Related articles - All 5 versions
[CITATION] Group NDD (1995) Diabetes in America
LS Geiss, WH Herman, PJ Smith - Bethesda, MD: National Institutes of Health, National … Cited by 3 - Related articles
T Lu, PVG Katakam, M VanRollins, NL … - The Journal of …, 2001 - Physiological Soc Dihydroxyeicosatrienoic acids (DHETs), which are metabolites of arachidonic acid (AA) and
epoxyeicosatrienoic acids (EETs), have been identified as highly potent endogenous
vasodilators, but the mechanisms by which DHETs induce relaxation of vascular smooth ... Cited by 47 - Related articles - BL Direct - All 7 versions
