- ►shouxi.net D Detaille, B Guigas, C Chauvin, C Batandier … - Diabetes, 2005 - Am Diabetes Assoc Hyperglycemia-induced oxidative stress is detrimental for endothelial cells,
contributing to the vascular complications of diabetes. The mitochondrial
permeability transition pore (PTP) is an oxidative stress–sensitive ... Cited by 46 - Related articles - All 5 versions
B Guigas, D Detaille, C Chauvin, C Batandier … - Biochemical Journal, 2004 - pubmedcentral.nih.gov Metformin, a drug widely used in the treatment of Type II diabetes, has recently
received attention owing to new findings regarding its mitochondrial and
cellular effects. In the present study, the effects of metformin on ... Cited by 34 - Related articles - BL Direct - All 8 versions
C Batandier, B Guigas, D Detaille, M El-Mir, … - Journal of bioenergetics and biomembranes, 2006 - Springer Page 1. J Bioenerg Biomembr (2006) 38:33–42 DOI 10.1007/s10863-006-9003-8 ORIGINAL
PAPER The ROS production induced by a reverse-electron flux at ... Cited by 26 - Related articles - BL Direct - All 3 versions
- ►nih.gov [PDF] B Sibille, C Filippi, MA Piquet, P Leclercq, E … - Biochemical Journal, 2001 - pubmedcentral.nih.gov In isolated mitochondria the consequences of oxidative phosphorylation
uncoupling are well defined, whereas in intact cells various effects have been
described. Uncoupling liver cells with 2,4-dinitrophenol (DNP) in the ... Cited by 14 - Related articles - BL Direct - All 7 versions
- ►pubget.com [PDF] MY El-Mir, D Detaille, G R-Villanueva, M … - Journal of Molecular Neuroscience, 2008 - Springer Abstract Oxidative damage has been reported to be involved in the pathogenesis
of diabetic neuropathy and neurodegenerative diseases. Recent evidence suggests
that the antidiabetic drug metformin prevents oxidative stress- related ... Cited by 5 - Related articles - BL Direct - All 3 versions
F Grenoble - biochemj.org Page 1. Metformin inhibits mitochondrial permeability transition and cell death:
a pharmacological in vitro study Bruno Guigas, Dominique ... Related articles - View as HTML
GF Azzone, M Zoratti, V Petronilli, D Pietrobon - Journal of inorganic biochemistry - ncbi.nlm.nih.gov It is suggested that loose coupling in free energy transducing organelles is due
partly to leaks through the phospholipid bilayer (extrinsic uncoupling) and
partly to "slipping" of the proton pumps (intrinsic uncoupling). The flow ... Cited by 11 - Related articles
C Bellin, DH de Wiza, NF Wiernsperger, P … - Hormone and metabolic research. Hormon-und …, 2006 - ncbi.nlm.nih.gov There is evidence that reactive oxygen intermediates (ROI) play an important
role in the pathogenesis of vascular complications in diabetes. On the other
hand, metformin, one of the most often used antidiabetic compounds has not ... Cited by 16 - Related articles - BL Direct - All 3 versions
[CITATION] Effects of metformin on metabolic indices of cerebral and peripheral ischaemia
WJH Koopman, F Distelmaier, JJ Esseling, … - Methods, 2008 - Elsevier Mitochondria are crucial for many aspects of cellular homeostasis and a
sufficiently negative membrane potential (Δψ) across the mitochondrial inner
membrane (MIM) is required to sustain most mitochondrial functions ... Cited by 7 - Related articles - All 6 versions
