- ►shouxi.net JJ Meier, G Kemmeries, JJ Holst, MA Nauck - Diabetes, 2005 - Am Diabetes Assoc Glucagon-like peptide 1 (GLP-1) has been proposed to act as an incretin hormone
due to its ability to enhance glucose-stimulated insulin secretion. Because
GLP-1 also decelerates gastric emptying, it physiologically reduces rather ... Cited by 33 - Related articles - All 6 versions
- ►endojournals.org JJ Meier, B Gallwitz, S Salmen, O Goetze, JJ … - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc The effects of different iv doses of glucagon-like peptide 1 (GLP-1) on glucose
homeostasis and gastric emptying were compared in patients with type 2 diabetes.
Twelve patients with type 2 diabetes received three different infusion ... Cited by 121 - Related articles - BL Direct - All 5 versions
MA Nauck, A El-Ouaghlidi, B Gabrys, K … - Regulatory peptides, 2004 - Elsevier Aims/Hypothesis: Since insulin secretion in response to exogenous gastric
inhibitory polypeptide (GIP) is diminished not only in patients with type 2
diabetes, but also in their normal glucose-tolerant first-degree relatives, ... Cited by 33 - Related articles - All 3 versions
- ►endojournals.org DG O'Donovan, S Doran, C Feinle-Bisset, KL … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc The determinants of postprandial blood glycemia are controversial. We assessed
the effects of variations in the initial rate of small intestinal glucose
delivery on blood glucose, plasma insulin, and incretin responses in both ... Cited by 52 - Related articles - All 9 versions
A Vella, P Shah, A Reed, A Adkins, R Basu, R … - Diabetologia, 2002 - Springer Aims/hypothesis. The aim of this study was to determine whether rapid conversion
to inactive and potentially an- tagonistic peptides could alter the response to
GLP-1. Methods. We evaluated the ability of exendin-4, a GLP-1 analogue ... Cited by 41 - Related articles - BL Direct - All 4 versions
- ►physiology.org JJ Meier, A Gethmann, MA Nauck, O Gotze, F … - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc Glucagon-like peptide 1 (GLP-1) lowers glycemia by modulating gastric emptying
and endocrine pancreatic secretion. Rapidly after its secretion, GLP-1-(7–36)
amide is degraded to the metabolite GLP-1-(9–36) amide. The effects of ... Cited by 21 - Related articles - BL Direct - All 3 versions
DO'Donovan, M Horowitz, A Russo, C Feinle- … - Diabetologia, 2004 - Springer Aims/hypotheses. We examined the effects of lipase inhibition with orlistat on
(i) gastric emptying of, and (ii) the glycaemic, glucagon-like peptide-1 (GLP-1)
and cardiovascular responses to, a high-fat/carbohy- drate meal in type 2 ... Cited by 22 - Related articles - All 4 versions
- ►bmj.com [PDF] J Schirra, M Nicolaus, R Roggel, M … - British Medical Journal, 2005 - gut.bmj.com Online First articles must include the digital object identifier (DOIs) and date
of initial publication. establish publication priority; they are indexed by
PubMed from initial publication. Citations to may be posted when available ... Cited by 53 - Related articles - BL Direct - All 8 versions
- ►endojournals.org TJ Little, AN Pilichiewicz, A Russo, L … - Journal of Clinical Endocrinology & Metabolism, 2006 - Endocrine Soc Results: GLP-1 0.3 and 0.9 slowed GE of solid (intragastric retention at t = 100
min; saline: 28 ± 5%; GLP-1 0.3: 53 ± 6%; GLP-1 0.9: 58 ± 7%; P < 0.001) and
liquid (time for 50% of the liquid to empty, saline: 28 ± 2 min; GLP-1 ... Cited by 27 - Related articles - BL Direct - All 4 versions
JJ Meier, MA Nauck - Diabetes/Metabolism Reviews - interscience.wiley.com Post-translational proteolytic processing of the preproglucagon gene in the gut
results in the formation of glucagon-like peptide 1 (GLP-1). Owing to its
glucose-dependent insulinotropic effect, this hormone was postulated to ... Cited by 73 - Related articles - All 3 versions
