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Scholar Results 1 - 10 of about 101 related to Cancello: Reduction of macrophage infiltration and chemoattractant gene expression changes.... (0.08 sec) 

Reduction of macrophage infiltration and chemoattractant gene expression …


R Cancello, C Henegar, N Viguerie, S Taleb, C Poitou, … - Diabetes, 2005 - Am Diabetes Assoc
In human obesity, the stroma vascular fraction (SVF) of white adipose tissue (WAT) is enriched
in macrophages. These cells may contribute to low-grade inflammation and to its metabolic
complications. Little is known about the effect of weight loss on macrophages and genes ...
Cited by 251 - Related articles - BL Direct - All 5 versions

Adipocyte death defines macrophage localization and function in adipose tissue of …

- jlr.org
S Cinti, G Mitchell, G Barbatelli, I Murano, E Ceresi, … - The Journal of Lipid …, 2005 - ASBMB
Macrophage infiltration of white adipose tissue (WAT) is implicated in the metabolic complications
of obesity. The precipitating event(s) and function(s) of macrophage infiltration into WAT are
unknown. We demonstrate that >90% of all macrophages in WAT of obese mice and ...
Cited by 288 - Related articles - BL Direct - All 8 versions

Weight loss regulates inflammation-related genes in white adipose tissue of obese …

- fasebj.org
K Clement, N Viguerie, C Poitou, C Carette, V Pelloux, … - The FASEB Journal, 2004 - FASEB
Adipose tissue produces inflammation and immunity molecules suspected to be involved in
obesity-related complications. The pattern of expression and the nutritional regulation of these
molecules in humans are poorly understood. We analyzed the gene expression profiles ...
Cited by 215 - Related articles - BL Direct - All 8 versions

Increased infiltration of macrophages in omental adipose tissue is associated with …


R Cancello, J Tordjman, C Poitou, G Guilhem, JL … - Diabetes, 2006 - Am Diabetes Assoc
In human obesity, white adipose tissue (WAT) is enriched in macrophages. How macrophage
infiltration in WAT contributes to the complications of obesity is unknown. This study tested the
hypothesis that recruitment of macrophages in omental WAT is associated with hepatic ...
Cited by 112 - Related articles - BL Direct - All 5 versions

From Blood Monocytes to Adipose Tissue-Resident Macrophages


CA Curat, A Miranville, C Sengenès, M Diehl, C Tonus, … - Diabetes, 2004 - Am Diabetes Assoc
Obesity has been suggested to be a low-grade systemic inflammatory state, therefore we studied
the interaction between human adipocytes and monocytes via adipose tissue (AT)-derived capillary
endothelium. Cells composing the stroma-vascular fraction (SVF) of human ATs were ...
Cited by 218 - Related articles - BL Direct - All 4 versions

CCR2 modulates inflammatory and metabolic effects of high-fat feeding

- nih.gov
SP Weisberg, D Hunter, R Huber, J … - Journal of Clinical …, 2005 - Am Soc Clin Investig
The CC motif chemokine receptor–2 (CCR2) regulates monocyte and macrophage recruitment
and is necessary for macrophage-dependent inflammatory responses and the development
of atherosclerosis. Although adipose tissue expression and circulating concentrations of ...
Cited by 318 - Related articles - BL Direct - All 14 versions

Macrophage-secreted factors induce adipocyte inflammation and insulin resistance


PA Permana, C Menge, PD Reaven - Biochemical and biophysical research …, 2006 - Elsevier
Macrophage infiltration into adipose tissue increases with obesity, a condition associated with
low-grade inflammation and insulin resistance. We investigated the direct effects of
macrophage-secreted factors on adipocyte inflammation and insulin resistance. 3T3-L1 ...
Cited by 106 - Related articles - All 5 versions

MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance …

- nih.gov
H Kanda, S Tateya, Y Tamori, K Kotani, K … - Journal of Clinical …, 2006 - Am Soc Clin Investig
Adipocytes secrete a variety of bioactive molecules that affect the insulin sensitivity of other
tissues. We now show that the abundance of monocyte chemoattractant protein–1 (MCP-1) mRNA
in adipose tissue and the plasma concentration of MCP-1 were increased both in ...
Cited by 305 - Related articles - BL Direct - All 13 versions

Expression of CD68 and macrophage chemoattractant protein-1 genes in human …

- diabetesjournals.org
GB Di Gregorio, A Yao-Borengasser, N Rasouli, V … - Diabetes, 2005 - Am Diabetes Assoc
To examine the role of adipose-resident macrophages in insulin resistance, we examined the
gene expression of CD68, a macrophage marker, along with macrophage chemoattractant
protein-1 (MCP-1) in human subcutaneous adipose tissue using real-time RT-PCR. Both ...
Cited by 142 - Related articles - BL Direct - All 5 versions

Role of macrophage tissue infiltration in metabolic diseases


A Bouloumié, CA Curat, C Sengenès, K … - Current Opinion in …, 2005 - journals.lww.com
Purpose of review White adipose tissue is necessary for optimal energy homeostasis and the
excessive development of fat mass is clearly associated with the metabolic syndrome. The fact
that adipocytes secrete a number of specific factors or 'adipokines' has forced a ...
Cited by 114 - Related articles - All 5 versions


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