- ►diabetesjournals.org B Janssen, D Hohenadel, P Brinkkoetter, V Peters, N … - Diabetes, 2005 - Am Diabetes Assoc The risk of diabetic nephropathy is partially genetically determined. Diabetic nephropathy is linked
to a gene locus on chromosome 18q22.3-q23. We aimed to identify the causative gene on chromosome
18 and to study the mechanism by which the product of this gene could be involved in the ... Cited by 81 - Related articles - BL Direct - All 8 versions
I Vardarli, LJ Baier, RL Hanson, I Akkoyun, C Fischer, … - Kidney international, 2002 - nature.com Diabetic nephropathy is the major cause of end-stage renal failure in patients with diabetes mellitus
types 1 and 2. Epidemiological studies have suggested a genetic susceptibility to diabetic
nephropathy. The aim of this study was to localize the gene(s) responsible for ... Cited by 91 - Related articles - BL Direct - All 5 versions
- ►oxfordjournals.org BI Freedman, PJ Hicks, MM Sale, ED Pierson, CD … - Nephrology Dialysis …, 2007 - ERA-EDTA Background. Four linkage analyses have identified a region on chromosome 18q22-23 that appears
to harbour a diabetic nephropathy (DN) susceptibility locus. A trinucleotide repeat sequence
in exon 2 of the carnosinase gene (CNDP1) residing on 18q22.3 was subsequently ... Cited by 32 - Related articles - BL Direct - All 4 versions
DW Bowden, CJ Colicigno, CD LANGEFELD, MM … - Kidney international, 2004 - nature.com DNA samples were collected from 206 type 2 diabetes (T2DM) and end-stage renal disease
(ESRD)/nephropathy-affected sib pairs from 166 African American families (355 affected
individuals). A genome scan was performed and data analyzed using nonparametric ... Cited by 85 - Related articles - BL Direct - All 4 versions
SK Iyengar, HE Abboud, KAB Goddard, MF Saad, SG … - Diabetes, 2007 - Am Diabetes Assoc The Family Investigation of Nephropathy and Diabetes (FIND) was initiated to map genes underlying
susceptibility to diabetic nephropathy. A total of 11 centers participated under a single collection
protocol to recruit large numbers of diabetic sibling pairs concordant and discordant for ... Cited by 37 - Related articles - BL Direct - All 8 versions
JD Center, AS Krolewski… - Kidney international, 2006 - mhp.koshigaya.saitama.jp Nominal P-values foe evidence for linkage in all relatives on 22 q, 5q and 7q were lower than
empirical, indicating that the nominal P-values may have slightly overstated the evidence for
linkage to these regions. In contrast, the support for linkage of logACR to chromosome 21 ... Cited by 42 - Related articles - BL Direct - All 4 versions
KG Ewens, RA George, K Sharma, FN Ziyadeh, RS … - Diabetes, 2005 - Am Diabetes Assoc Several lines of evidence, including familial aggregation, suggest that allelic variation contributes
to risk of diabetic nephropathy. To assess the evidence for specific susceptibility genes, we used
the transmission/disequilibrium test (TDT) to analyze 115 candidate genes for linkage ... Cited by 34 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org AP Boright, AD Paterson, L Mirea, SB Bull, A Mowjoodi, … - Diabetes, 2005 - Am Diabetes Assoc The development and progression of microvascular complications have been extensively documented
in a cohort of type 1 diabetic subjects enrolled in the Diabetes Control and Complications Trial
(DCCT) and followed in the Epidemiology of Diabetes Interventions and Complications ( ... Cited by 46 - Related articles - All 6 versions
- ►oxfordjournals.org JM Leon, BI Freedman, MB Miller, KE North, SC … - Nephrology Dialysis …, 2007 - ERA-EDTA Results. The phenotypic correlation between ACR and GFR was not significant in EAs (r =
0.04) and significantly negative in AAs (r = –0.17). Univariate analyses of ACR showed suggestive
evidence of linkage on chromosomes 8, 16 and 17 (LOD: 2–2.8) in AAs, on chromosomes ... Cited by 18 - Related articles - BL Direct - All 4 versions
Y Lee, C Hsu, M Lin, K Liu, M Yin - European journal of pharmacology, 2005 - Elsevier In vivo effects of histidine and carnosine against diabetic deterioration in diabetic Balb/cA mice
were studied. Histidine and carnosine at 0.5, 1 g/l were added into drinking water. After 4 weeks
intake of these agents, the content of histidine and carnosine in plasma, heart and liver ... Cited by 30 - Related articles - All 4 versions
