- ►diabetesjournals.org Z Wang, T Jiang, J Li, G Proctor, JL … - Diabetes, 2005 - Am Diabetes Assoc Diabetic kidney disease has been associated with the presence of lipid deposits,
but the mechanisms for the lipid accumulation have not been fully determined. In
the present study, we found that db/db mice on the FVB genetic background ... Cited by 45 - Related articles - BL Direct - All 5 versions
- ►asnjournals.org T Jiang, SE Liebman, MS Lucia, CL Phillips, M … - Journal of the American Society of Nephrology, 2005 - Am Soc Nephrol Sterol regulatory element binding proteins (SREBP) are major regulators of fatty
acid and cholesterol synthesis. This study found that age-related renal matrix
deposition and proteinuria were associated with increased renal expression ... Cited by 15 - Related articles - BL Direct - All 7 versions
- ►jbc.org L Sun, N Halaihel, W Zhang, T Rogers, M Levi - Journal of Biological Chemistry, 2002 - ASBMB Diabetic renal disease is associated with lipid deposits in the kidney. The
purpose of our study was to determine whether there is altered regulation of the
sterol regulatory element-binding proteins (SREBPs) in the diabetic kidney ... Cited by 83 - Related articles - BL Direct - All 5 versions
- ►jbc.org T Jiang, Z Wang, G Proctor, S Moskowitz, SE … - Journal of Biological Chemistry, 2005 - ASBMB Obesity and metabolic syndrome are associated with glomerulosclerosis and
proteinuria, but the mechanisms are not known. The purpose of this study was to
determine if there is altered renal lipid metabolism and increased ... Cited by 58 - Related articles - BL Direct - All 5 versions
T Jiang, SE Liebman, MS Lucia, J Li, M Levi - Kidney international, 2005 - nature.com There are well-known changes in age-related renal function and structure,
including glomerulosclerosis and decline in glomerular filtration rate (GFR).
The purpose of this study was to identify a potential role for lipids in ... Cited by 31 - Related articles - BL Direct - All 5 versions
- ►shouxi.net G Proctor, T Jiang, M Iwahashi, Z Wang, J Li, … - Diabetes, 2006 - Am Diabetes Assoc In Akita and OVE26 mice, two genetic models of type 1 diabetes, diabetic
nephropathy is characterized by mesangial expansion and loss of podocytes,
resulting in glomerulosclerosis and proteinuria, and is associated with ... Cited by 29 - Related articles - BL Direct - All 5 versions
N Ishigaki, T Yamamoto, Y Shimizu, K … - Biochemical and Biophysical Research …, 2007 - Elsevier The role of glomerular SREBP-1c in diabetic nephropathy was investigated.
PEPCK-promoter transgenic mice overexpressing nuclear SREBP-1c exhibited
enhancement of proteinuria with mesangial proliferation and matrix ... Cited by 6 - Related articles - All 3 versions
- ►amjpathol.org RA Zager, A Johnson, SY Hanson, VO Shah - American Journal of Pathology, 2003 - ASIP Acute renal injury causes accumulation of free and esterified cholesterol (FC,
CE) in proximal tubules, mediated, at least in part, by increased cholesterol
synthesis. Normally, this would trigger compensatory mechanisms such as ... Cited by 17 - Related articles - BL Direct - All 6 versions
CK Abrass - Am J Nephrol, 2004 - content.karger.com Dyslipidemia contributes to the rate of progression of atherosclerosis and
chronic kidney disease. Also, chronic kidney disease leads to the development of
secondary abnormalities in lipid metabolism that contribute to increased ... Cited by 58 - Related articles - BL Direct - All 6 versions
P Balakumar, VA Chakkarwar, P Krishan, M … - Biomedicine & Pharmacotherapy, 2009 - Elsevier Vascular endothelium regulates vascular tone and maintains free flow of blood in
vessels. Vascular endothelial dysfunction (VED) results in reduced activation of
endothelial nitric oxide synthase (eNOS), reduced generation and ... Cited by 9 - Related articles - All 2 versions
