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Scholar Results 1 - 10 of about 101 related to MacLellan: Physiological increases in uncoupling protein 3 augment fatty acid oxidation and.... (0.11 sec) 

Physiological increases in uncoupling protein 3 augment fatty acid oxidation and decrease …

- shouxi.net
JD MacLellan, MF Gerrits, A Gowing, PJS … - Diabetes, 2005 - Am Diabetes Assoc
Decreased uncoupling protein (UCP)3 is associated with insulin resistance in
muscle of pre-diabetic and diabetic individuals, but the function of UCP3
remains unclear. Our goal was to elucidate mechanisms underlying the ...
Cited by 79 - Related articles - BL Direct - All 9 versions

Constitutive UCP3 overexpression at physiological levels increases mouse skeletal muscle …

- fasebj.org [PDF] 
V Bezaire, LL Spriet, S Campbell, N Sabet, M … - The FASEB Journal, 2005 - FASEB
The FASEB Journal express article 10.1096/fj.04-2765fje. Published online April
6, 2005. ... V. Bezaire,* LL Spriet,* S. Campbell,* N. Sabet, ... † M.
Gerrits, † A. Bonen,* and M.-E. Harper † ... *Department of Human ...
Cited by 50 - Related articles - All 6 versions

The role of uncoupling protein 3 in fatty acid metabolism: protection against lipotoxicity?


P Schrauwen - Proceedings of the Nutrition Society, 2007 - Cambridge Univ Press
The physiological function of the mitochondrial uncoupling protein (UCP), UCP3,
is still under debate. There is, however, ample evidence to indicate that, in
contrast to UCP1, the primary function of UCP3 is not the dissipation of ...
Cited by 44 - Related articles - BL Direct - All 4 versions

Uncoupling protein 3 content is decreased in skeletal muscle of patients with type 2 diabetes

- unimaas.nl [PDF] 
P Schrauwen, MKC Hesselink, EE Blaak, LB … - Diabetes, 2001 - Am Diabetes Assoc
Recently, a role for uncoupling protein-3 (UCP3) in carbohydrate metabolism and
in type 2 diabetes has been suggested. Mice overexpressing UCP3 in skeletal
muscle showed reduced fasting plasma glucose levels, improved glucose ...
Cited by 67 - Related articles - BL Direct - All 6 versions

Effects of the presence, absence, and overexpression of uncoupling protein-3 on adiposity …

- physiology.org
SR Costford, SN Chaudhry, M Salkhordeh, … - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc
Uncoupling protein-3 (UCP3) is a poorly understood mitochondrial inner membrane
protein expressed predominantly in skeletal muscle. The aim of this study was to
examine the effects of the absence or constitutive physiological ...
Cited by 13 - Related articles - BL Direct - All 3 versions

Physiological role of UCP3 may be export of fatty acids from mitochondria when fatty acid …

- ebmonline.org
J Himms-Hagen, ME Harper - Experimental Biology and Medicine, 2001 - SEBM
This hypothesis proposes a physiological role for uncoupling protein-3 (UCP3) in
the export of fatty acid anions from muscle and brown adipose tissue (BAT)
mitochondria when fatty acids are the predominant substrate being used. It ...
Cited by 208 - Related articles - BL Direct - All 3 versions

The basal proton conductance of skeletal muscle mitochondria from transgenic mice …


S Cadenas, KS Echtay, JA Harper, MB … - Journal of Biological Chemistry, 2002 - ASBMB
The ability of native uncoupling protein-3 (UCP3) to uncouple mitochondrial
oxidative phosphorylation is controversial. We measured the expression level of
UCP3 and the proton conductance of skeletal muscle mitochondria isolated ...
Cited by 125 - Related articles - BL Direct - All 5 versions

Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3


MD Brand, TC Esteves - Cell Metabolism, 2005 - Elsevier
Uncoupling proteins (UCPs) have become prominent in the fields of thermogenesis,
obesity, diabetes, and free radical biology following the discovery of a family
of novel UCPs and have recently started to make an impact in the areas of ...
Cited by 179 - Related articles - All 10 versions

Oxidative damage and phospholipid fatty acyl composition in skeletal muscle mitochondria …

- nih.gov [PDF] 
MD Brand, R Pamplona, M Portero-Otín, JR … - Biochemical Journal, 2002 - pubmedcentral.nih.gov
Five markers of different kinds of oxidative damage to proteins [glutamic
semialdehyde, aminoadipic semialdehyde, Nε-(carboxy- methyl)lysine,
Nε-(carboxyethyl)lysine and Nε-(malondialde- hyde)lysine] and ...
Cited by 104 - Related articles - BL Direct - All 9 versions

Expression of UCP3 in CHO cells does not cause uncoupling, but controls mitochondrial …


J Mozo, G Ferry, A Studeny, C Pecqueur, M … - Biochemical Journal, 2006 - pubmedcentral.nih.gov
The proton-transport activity of UCP1 (uncoupling protein 1) triggers
mitochondrial uncoupling and thermogenesis. The exact role of its close
homologues, UCP2 and UCP3, is unclear. Mounting evidence associates them ...
Cited by 29 - Related articles - BL Direct - All 8 versions


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