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Scholar Results 1 - 10 of about 101 related to Wynne: Subcutaneous oxyntomodulin reduces body weight in overweight and obese subjects. (0.15 sec) 

Subcutaneous oxyntomodulin reduces body weight in overweight and obese subjects


K Wynne, AJ Park, CJ Small, M Patterson, SM … - Diabetes, 2005 - Am Diabetes Assoc
This study investigated the effect of subcutaneously administered oxyntomodulin
on body weight in healthy overweight and obese volunteers. Participants
self-administered saline or oxyntomodulin subcutaneously in a randomized, ...
Cited by 87 - Related articles - BL Direct - All 8 versions

Peripheral oxyntomodulin reduces food intake and body weight gain in rats

- endojournals.org
CL Dakin, CJ Small, RL Batterham, NM Neary … - Endocrinology, 2004 - Endocrine Soc
Oxyntomodulin (OXM) is a circulating gut hormone released post prandially from
cells of the gastrointestinal mucosa. Given intracerebroventricularly to rats,
it inhibits food intake and promotes weight loss. Here we report that ...
Cited by 115 - Related articles - BL Direct - All 9 versions

Oxyntomodulin increases energy expenditure in addition to decreasing energy intake in …


K Wynne, AJ Park, CJ Small, K Meeran, MA … - International Journal of Obesity, 2006 - nature.com
International Journal of Obesity is a monthly, multi-disciplinary forum for papers
describing basic, clinical and applied studies in biochemistry, genetics and ...
Cited by 45 - Related articles - BL Direct - All 4 versions

Oxyntomodulin suppresses appetite and reduces food intake in humans

- endojournals.org
MA Cohen, SM Ellis, CW Le Roux, RL … - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc
Oxyntomodulin (OXM) is released from the gut postprandially, in proportion to
energy intake, and circulating levels of OXM are elevated in several conditions
associated with anorexia. Central injection of OXM reduces food intake and ...
Cited by 180 - Related articles - BL Direct - All 5 versions

Oxyntomodulin and glucagon-like peptide-1 differentially regulate murine food intake and …

- glucagon.com [PDF] 
LL Baggio, Q Huang, TJ Brown, DJ Drucker - Gastroenterology, 2004 - Elsevier
Gut-derived peptides including ghrelin, cholecystokinin (CCK), peptide YY (PYY),
glucagon-like peptide (GLP-1), and GLP-2 exert overlapping actions on energy
homeostasis through defined G-protein-coupled receptors (GPCRs). The ...
Cited by 89 - Related articles - BL Direct - All 12 versions

Repeated ICV administration of oxyntomodulin causes a greater reduction in body weight gain …

- physiology.org
CL Dakin, CJ Small, AJ Park, A Seth, MA … - American Journal of Physiology- Endocrinology And …, 2002 - Am Physiological Soc
Oxyntomodulin (OXM) is a product of proglucagon processing in the intestine and
the central nervous system. We reported that intracerebroventricular (ICV) and
intranuclear administration of OXM caused an inhibition of food intake in ...
Cited by 54 - Related articles - BL Direct - All 5 versions

Oxyntomodulin inhibits food intake in the rat

- endojournals.org
CL Dakin, I Gunn, CJ Small, CMB Edwards, … - Endocrinology, 2001 - Endocrine Soc
Oxyntomodulin is derived from proglucagon processing in the intestine and the
central nervous system. To date, no role in the central nervous system has been
demonstrated. We report here that oxyntomodulin inhibits refeeding when ...
Cited by 109 - Related articles - BL Direct - All 3 versions

Oxyntomodulin: a potential hormone from the distal gut. Pharmacokinetics and effects on …


BT Schjoldager, FG Baldissera, PE Mortensen, … - Eur J Clin Invest, 1988 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 37 - Related articles - All 2 versions

Oxyntomodulin-like immunoreactivity: diurnal profile of a new potential enterogastrone


A Le Quellec, A Kervran, P Blache, AJ Ciurana … - Journal of Clinical Endocrinology & Metabolism, 1992 - Endocrine Soc
ABSTRACT. The biological specificity of oxyntomodulin to- ward the gastric
mucosa results from its C-terminal octapeptide. A RIA using a specific antibody
raised against this region per- mitted quantification of the whole set of ...
Cited by 45 - Related articles - All 3 versions

Pancreatic polypeptide reduces appetite and food intake in humans


RL Batterham, CW Le Roux, MA Cohen, AJ Park … - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc
Pancreatic polypeptide (PP) is a gut hormone released from the pancreas in
response to ingestion of food. Plasma PP has been shown to be reduced in
conditions associated with increased food intake and elevated in anorexia ...
Cited by 177 - Related articles - BL Direct - All 6 versions


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