DJ Angiolillo, A Fernandez-Ortiz, E Bernardo, C … - Diabetes, 2005 - Am Diabetes Assoc To assess platelet function profiles in diabetic and nondiabetic patients on aspirin and clopidogrel
therapy, two patient populations were included to investigate the 1) acute effects of a 300-mg
clopidogrel loading dose (group 1, n = 52) and 2) long-term effects of clopidogrel (group ... Cited by 120 - Related articles - BL Direct - All 5 versions
- ►onlinejacc.org DJ Angiolillo, E Bernardo, C Ramírez, MA Costa, M … - Journal of the American …, 2006 - Elsevier Insulin inhibits platelet aggregation by suppressing the P2Y 12 pathway. However, T2DM patients
have a loss of responsiveness to insulin that leads to upregulation of the P2Y 12 pathway, increased
platelet reactivity, and reduced responsiveness to antiplatelet agents. Patients with ... Cited by 79 - Related articles - BL Direct - All 23 versions
DJ Angiolillo, A Fernandez-Ortiz, E Bernardo, C … - Thrombosis research, 2005 - Elsevier Platelet aggregation was assessed by light transmittance aggregometry following 6 μM ADP
stimuli in 48 patients before and 10 min, 4 and 24 h after receiving clopidogrel front-loading.
Patients having ≥40% inhibition of platelet aggregation 24 h after clopidogrel ... Cited by 101 - Related articles - All 7 versions
- ►ahajournals.org DJ Angiolillo, SB Shoemaker, B Desai, H Yuan, RK … - Circulation, 2007 - Am Heart Assoc Methods and Results— T2DM patients on chronic dual antiplatelet therapy were screened to
identify suboptimal clopidogrel responders. The latter were randomized to 30-day treatment with
a standard (75 mg; n=20) or high (150 mg; n=20) daily maintenance dose. Platelet ... Cited by 156 - Related articles - All 8 versions
- ►onlinejacc.org DJ Angiolillo, E Bernardo, M Sabaté, P Jimenez- … - Journal of the American …, 2007 - Elsevier Type 2 diabetes mellitus patients have increased platelet reactivity compared with nondiabetic
patients. Whether HPR assessed in T2DM while in their steady-state phase of dual antiplatelet
therapy is associated with an increased risk of major adverse cardiovascular events ... Cited by 62 - Related articles - BL Direct - All 33 versions
- ►onlinejacc.org DJ Angiolillo, A Fernandez-Ortiz, E Bernardo, F … - Journal of the American …, 2007 - Elsevier Antiplatelet therapy is the cornerstone of treatment for patients with acute coronary syndromes
and/or undergoing percutaneous coronary interventions. Clopidogrel, in combination with
aspirin, is currently the antiplatelet treatment of choice for prevention of stent thrombosis, ... Cited by 156 - Related articles - BL Direct - All 19 versions
- ►diabetesjournals.org T Geisler, N Anders, M Paterok, H Langer, K Stellos … - Diabetes Care, 2007 - Am Diabetes Assoc Type 2 diabetes is accompanied by platelet function disorders leading to an accelerated process
of atherosclerosis and increased risk for atherothrombotic complications (1–4). Previous data
(5,6) suggest a worse outcome for diabetic patients after acute coronary events. Recently, ... Cited by 26 - Related articles - BL Direct - All 9 versions
- ►ahajournals.org [PDF] IA Ferreira, AIM Mocking, MAH Feijge, G … - … , and vascular biology, 2006 - Am Heart Assoc Kluwer Health, 351 West Camden Street, Baltimore, MD 21202-2436. Phone:
410-528-4050. Permissions: Permissions & Rights Desk, Lippincott Williams & Wilkins, a division
of Wolters ... Platelet Inhibition by Insulin Is Absent in Type 2 ... Irlando Andrade Ferreira, ... Cited by 37 - Related articles - All 9 versions
- ►onlinejacc.org PA Gurbel, KP Bliden, K Guyer, PW Cho, KA Zaman … - Journal of the American …, 2005 - Elsevier We measured platelet reactivity to adenosine diphosphate (ADP) by light transmittance aggregometry
(LTA) in patients undergoing PCI (n = 192). Clot strength, a measure of thrombin-induced fibrin
and platelet interactions, and the time to initial fibrin generation, a marker of thrombin ... Cited by 216 - Related articles - BL Direct - All 16 versions
- ►oxfordjournals.org DJ Angiolillo, A Fernandez-Ortiz, E Bernardo, … - European heart …, 2004 - Eur Soc Cardiology METHODS AND RESULTS: Platelet function profiles were assessed in 50 patients undergoing
coronary stenting receiving either a 300 mg (n=27) or 600 mg clopidogrel LD. ADP (6 μM) and
collagen (6 μg/mL) induced platelet aggregation, as well as ADP (2 μM) induced ... Cited by 171 - Related articles - All 3 versions
