VA Gault, N Irwin, BD Green, JT McCluskey, B Greer, … - Diabetes, 2005 - Am Diabetes Assoc Glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide [GIP]) is an important
incretin hormone secreted by endocrine K-cells in response to nutrient ingestion. In this
study, we investigated the effects of chemical ablation of GIP receptor (GIP-R) action on ... Cited by 52 - Related articles - BL Direct - All 8 versions
H Zhou, Y Yamada, K Tsukiyama, K Miyawaki, M … - … and Biophysical Research …, 2005 - Elsevier Gut hormone gastric inhibitory polypeptide (GIP) stimulates insulin secretion from pancreatic
β-cells upon ingestion of nutrients. Inhibition of GIP signaling prevents the onset of obesity and
consequent insulin resistance induced by high-fat diet. In this study, we investigated the ... Cited by 31 - Related articles - All 4 versions
N Irwin, PL McClean, FPM O'Harte, VA Gault, P Harriott, … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Ablation of gastric inhibitory polypeptide (GIP) receptor action is reported
to protect against obesity and associated metabolic abnormalities. The aim of this study was
to use prediabetic ob/ob mice to examine whether 60 days of chemical GIP receptor ... Cited by 26 - Related articles - BL Direct - All 5 versions
VA Gault, FPM O'Harte, P Harriott, PR Flatt - … and Biophysical Research …, 2002 - diabetica.co.uk A novel N-terminally substituted Pro3 analogue of glucose-dependent insulinotropic polypeptide
(GIP) was synthesized and tested for plasma stability and biological activity both in vitro and
in vivo. Native GIP was rapidly degraded by human plasma with only 39 6% remaining ... Cited by 44 - Related articles - BL Direct - All 8 versions
- ►diabetica.co.uk [PDF] N Irwin, VA Gault, BD Green, B Greer, JT … - Biological …, 2004 - reference-global.com Glucose-dependent insulinotropic polypeptide (GIP) is an incretin hormone secreted by endocrine
K-cells in response to nutrient absorption. In this study we have utilized a specific and enzymatically
stable GIP receptor antagonist, (Pro3)GIP, to evaluate the contribution of endogenous GIP ... Cited by 18 - Related articles - BL Direct - All 12 versions
J Sheffer, A Managing - diabetica.co.uk The site contains 1 file. You will need to have Adobe Acrobat® Reader software to read these
files. This is free software and is available for user downloading at http://www.adobe.com/products
/acrobat/readstep.html. ... 1) Reprint Order form 2) A copy of your page proofs for your ... Related articles - View as HTML - All 2 versions
- ►diabetica.co.uk [PDF] VA Gault, FPM O'Harte, PR Flatt - Neuropeptides, 2003 - Elsevier Glucose-dependent insulinotropic polypeptide (GIP or gastric inhibitory polypeptide) is a gastrointestinal
hormone, which modulates physiological insulin secretion. Due to its insulinotropic activity, there
has been a considerable increase of interest in utilising the hormone as a potential ... Cited by 53 - Related articles - All 10 versions
- ►nih.gov T Hansotia, A Maida, G Flock, Y Yamada, K … - Journal of Clinical …, 2006 - Am Soc Clin Investig The incretin hormones glucagon-like peptide–1 (GLP-1) and glucose-dependent insulinotropic
polypeptide (GIP) control glucose homeostasis through well-defined actions on the islet β cell
via stimulation of insulin secretion and preservation and expansion of β cell mass. We ... Cited by 54 - Related articles - BL Direct - All 9 versions
- ►physiology.org PL McClean, N Irwin, RS Cassidy, JJ Holst … - American Journal of …, 2007 - Am Physiological Soc The gut hormone gastric inhibitory polypeptide (GIP) plays a key role in glucose homeostasis
and lipid metabolism. This study investigated the effects of administration of a stable and specific
GIP receptor antagonist, (Pro 3 )GIP, in mice previously fed a high-fat diet for 160 days to ... Cited by 27 - Related articles - BL Direct - All 3 versions
K Miyawaki, Y Yamada, N Ban, Y Ihara, K Tsukiyama, … - Nature medicine, 2002 - nature.com Secretion of gastric inhibitory polypeptide (GIP), a duodenal hormone, is primarily induced by
absorption of ingested fat. Here we describe a novel pathway of obesity promotion via GIP.
Wild-type mice fed a high-fat diet exhibited both hypersecretion of GIP and extreme ... Cited by 219 - Related articles - BL Direct - All 6 versions
