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Scholar Results 1 - 10 of about 101 related to Siddiq: A synonymous coding polymorphism in the α2-Heremans-Schmid glycoprotein gene is.... (0.09 sec) 

A synonymous coding polymorphism in the α2-Heremans-Schmid glycoprotein …


A Siddiq, F Lepretre, S Hercberg, P Froguel, F Gibson - Diabetes, 2005 - Am Diabetes Assoc
AHSG is a multifunctional protein with diverse biological functions that include the regulation
of calcium homeostasis (6,7). A possible role for AHSG in influencing genetic susceptibility to
type 2 diabetes was first suggested by in vitro work demonstrating that AHSG inhibits, in a ...
Cited by 25 - Related articles - BL Direct - All 5 versions

a 2-Heremans–Schmid glycoprotein gene polymorphisms are associated with …


I Dahlman, P Eriksson, M Kaaman, H Jiao, CM … - Diabetologia, 2004 - Springer
Aims/hypothesis. The aim of this study was to investi- gate the effect of single-nucleotide polymorphisms
(SNPs) in the gene encoding the human α2-Here- mans–Schmid glycoprotein (AHSG) on obesity
and insulin action in adipocytes. Methods. We screened 24 individuals for SNPs in AHSG. ...
Cited by 29 - Related articles - All 3 versions

Association of serum fetuin-A with insulin resistance in type 2 diabetic and …

- diabetesjournals.org [PDF] 
K Mori, M Emoto, H Yokoyama, T Araki, M … - Diabetes Care, 2006 - Am Diabetes Assoc
To address this, we investigated the relationship of serum fetuin-A levels and insulin resistance
in nondiabetic (n = 160) and type 2 diabetic (n = 161) subjects. Serum fetuin-A was measured
by an enzyme-linked immunosorbent assay kit (BioVender Laboratory Medicine, Brno, ...
Cited by 27 - Related articles - BL Direct - All 5 versions

Differential expression of insulin receptor tyrosine kinase inhibitor (fetuin) gene in a …


X Lin, HD Braymer, GA Bray, DA York - Life Sciences, 1998 - Elsevier
ELSEVIER Ufe Sciences, Vol. 63, No. 2, pp. 145-153,1998 Copyright ° 1998 Elsevier Science
Inc. Printed in the USA. All rights reserved PH S0024-3205(98)00250-l 0024-3205/98 «9.oo
+ .oo DIFFERENTIAL EXPRESSION OF INSULIN RECEPTOR TYROSINE KINASE ...
Cited by 23 - Related articles - BL Direct - All 5 versions

Polymorphism of the AHSG gene is associated with increased adipocyte {beta} 2- …

- jlr.org
C Lavebratt, E Dungner, J Hoffstedt - The Journal of Lipid Research, 2005 - ASBMB
The alpha 2 Heremans-Schmid glycoprotein (AHSG) gene is implicated in the regulation of body
fat and insulin sensitivity. The Met/Met genotype of the common single-nucleotide polymorphism
(SNP), rs4917, in the AHSG gene has been shown to be associated with reduced plasma ...
Cited by 9 - Related articles - BL Direct - All 4 versions

AHSG gene variant is associated with leanness among Swedish men


C Lavebratt, S Wahlqvist, L Nordfors, J Hoffstedt, P … - Human genetics, 2005 - Springer
AHSG (alpha 2 Heremans-Schmid glycoprotein, also called fetuin-A in animals) is a liver-secreted
glycopro- tein that is abundant in plasma and mineralized bone and that is involved in several
diverse mechanisms, including osteogenesis and bone resorption, the regula- tion of the ...
Cited by 15 - Related articles - All 3 versions

α2-HSG, a specific inhibitor of insulin receptor autophosphorylation, interacts with …

- auburn.edu [PDF] 
ST Mathews, N Chellam, PR Srinivas, VJ Cintron, … - Molecular and Cellular …, 2000 - Elsevier
Human fetuin, (α 2 -Heremans Schmid Glycoprotein (α 2 -HSG)], is a natural inhibitor of insulin
receptor tyrosine kinase activity (IR-TKA). Previously, we have demonstrated that α 2 -HSG inhibits
the mitogenic pathway without affecting the metabolic arm of insulin signal transduction. ...
Cited by 51 - Related articles - All 5 versions

Correlation of maternal serum fetuin/alpha2-HS-glycoprotein concentration with …

- eje-online.org [PDF] 
L Kalabay, K Cseh, A Pajor, E Baranyi, GM Csakany, … - European Journal of …, 2002 - EFES
László Kalabay, Károly Cseh1, Attila Pajor3, Éva Baranyi4, György M Csákány5, Zsolt
Melczer3, Gábor Speer6, Margit Kovács, György Siller2, István Karádi and Gábor Winkler7 Third
Department of Internal Medicine Semmelweis University, Faculty of Medicine, 1First ...
Cited by 38 - Related articles - BL Direct - All 8 versions

A promoter polymorphism of the α2-HS glycoprotein gene is associated with its …


M Inoue, H Takata, Y Ikeda, T Suehiro, S Inada, F … - Diabetes Research and …, 2008 - Elsevier
Type 2 diabetes is characterized by insufficiency of insulin secretion and insulin resistance of
target tissues [1]. Both genes and the environment contribute to the development of the disease
[2]. Insulin mediates its actions through phosphorylation of the insulin receptor (IR), a ...
Cited by 6 - Related articles - All 14 versions

Fetuin-A induces cytokine expression and suppresses adiponectin production


AM Hennige, H Staiger, C Wicke, F Machicao, A … - PLoS ONE, 2008 - pubmedcentral.nih.gov
Human monocytic THP1 cells and human in vitro differenttiated adipocytes as well as
C57BL/6 mice were treated with fetuin-A. mRNA expression of the genes encoding inflammatory
cytokines and the adipokine adiponectin (ADIPOQ) was assessed by real-time RT-PCR. ...
Cited by 19 - Related articles - All 6 versions


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