- ►shouxi.net MN Weedon, KR Owen, B Shields, G Hitman, M … - Diabetes, 2005 - Am Diabetes Assoc HNF1α (TCF1) is a key transcription factor that is essential for pancreatic
β-cell development and function. Rare mutations of HNF1α cause maturity-onset
diabetes of the young. A common variant, G319S, private to the Oji-Cree ... Cited by 38 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org W Winckler, NP Burtt, J Holmkvist, C Cervin, … - Diabetes, 2005 - Am Diabetes Assoc It is currently unclear how often genes that are mutated to cause rare,
early-onset monogenic forms of disease also harbor common variants that
contribute to the more typical polygenic form of each disease. The gene for ... Cited by 46 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org MN Weedon, KR Owen, B Shields, G Hitman, M … - Diabetes, 2004 - Am Diabetes Assoc Hepatocyte nuclear factor (HNF)-4α is part of a transcription factor network
that is key for the development and function of the β-cell. Rare mutations in
the HNF4α gene cause maturity-onset diabetes of the young. A number of ... Cited by 85 - Related articles - BL Direct - All 5 versions
E Zeggini, JR Parkinson, S Halford, KR Owen … - Diabetic medicine, 2005 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 20 - Related articles - BL Direct - All 6 versions
SK Hansen, CS Rose, C Glümer, T Drivsholm, … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 452–458 DOI 10.1007/s00125-005-1671-0 ARTICLE SK
Hansen . CS Rose . C. Glümer . T. Drivsholm . K. Borch-Johnsen . ... Cited by 42 - Related articles - All 5 versions
- ►shouxi.net LL Bonnycastle, CJ Willer, KN Conneely, AU … - Diabetes, 2006 - Am Diabetes Assoc Prior reports have suggested that variants in the genes for maturity-onset
diabetes of the young (MODY) may confer susceptibility to type 2 diabetes, but
results have been conflicting and coverage of the MODY genes has been ... Cited by 40 - Related articles - BL Direct - All 10 versions
- ►diabetesjournals.org W Winckler, RR Graham, PIW de Bakker, M Sun … - Diabetes, 2005 - Am Diabetes Assoc Two recent publications reported association of common polymorphisms in the P2
promoter of hepatocyte nuclear factor 4α (HNF4α) (the MODY1 gene) with risk
for type 2 diabetes. We attempted to reproduce this putative association by ... Cited by 59 - Related articles - All 8 versions
- ►endojournals.org RA Hegele, H Cao, SB Harris, AJG Hanley, B … - Journal of Clinical Endocrinology & Metabolism, 1999 - Endocrine Soc Mutations in the gene encoding hepatic nuclear factor-1 (HNF-1 ) have been found
in patients with maturity-onset diabetes of the young. We identified a new
variant in the HNF-1 gene, namely G319S, in Ontario Oji-Cree with type 2 ... Cited by 86 - Related articles - BL Direct - All 4 versions
CS Rose, J Ek, SA Urhammer, C Glumer, K … - Diabetes, 2005 - Am Diabetes Assoc A graded relationship has been reported between fasting and postprandial plasma
glucose levels and the subsequent risk of cardiovascular morbidity and
mortality. We hypoth- esized that the GCK 30G>A promoter polymorphism is ... Cited by 23 - Related articles - BL Direct - All 5 versions
- ►shouxi.net MN Weedon, TM Frayling, B Shields, B Knight, … - Diabetes, 2005 - Am Diabetes Assoc Rare mutations in the glucokinase (GCK) gene cause fasting hyperglycemia and
considerably influence birth weight when present in a mother or her offspring.
The role of common variation of GCK is uncertain. A polymorphism at ... Cited by 58 - Related articles - All 13 versions
