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Scholar Results 1 - 10 of about 101 related to Devendra: Interferon-α as a mediator of polyinosinic: polycytidylic acid–induced type 1 diabetes. (0.15 sec) 

Interferon-α as a mediator of polyinosinic: polycytidylic acid–induced type 1 diabetes

- shouxi.net
D Devendra, J Jasinski, E Melanitou, M … - Diabetes, 2005 - Am Diabetes Assoc
A number of studies and clinical case reports have implicated interferon
(IFN)-α as a potential mediator of type 1 diabetes pathogenesis. Administration
of polyinosinic:polycytidylic acid (poly I:C), a mimic of viral ...
Cited by 25 - Related articles - BL Direct - All 5 versions

Double-stranded RNA induces pancreatic beta cell apoptosis by activation of the TLR3 and …

- diabetesjournals.org [PDF] 
Z Dogusan, M García, D Flamez, L … - Diabetes, 2008 - Am Diabetes Assoc
1 Laboratory of Experimental Medicine, Université Libre de Bruxelles, Brussels,
Belgium. 2 Centre d'Immunologie de Marseille-Luminy, CNRS-INSERM- Université de
la Mediterranée, Marseille, France. 3 Institute of Medical Immunology, ...
Cited by 8 - Related articles - All 2 versions

The effect of innate immunity on autoimmune diabetes and the expression of Toll-like …

- jimmunol.org
L Wen, J Peng, Z Li, FS Wong - The Journal of Immunology, 2004 - Am Assoc Immnol
Viral infections have previously been implicated as a trigger of autoimmune
diabetes. In this study, we compared a viral mimic with other microbial
components derived from bacteria in triggering diabetes development in ...
Cited by 60 - Related articles - All 4 versions

High incidence of type 1 diabetes mellitus during or shortly after treatment with pegylated …

- uva.nl [PDF] 
TC Schreuder, HC Gelderblom, CJ Weegink, … - Liver International, 2008 - medscape.com
We screened for DM during and after treatment with pegylated-IFN-α (Peg-IFN-α)
and Riba for chronic HCV infection. This started after we observed two index
cases of DM during Peg-IFN-α/Riba treatment in our hospital in December ...
Cited by 8 - Related articles - BL Direct - All 9 versions

Identification of a molecular signature in human type 1 diabetes mellitus using serum and …

- jimmunol.org
X Wang, S Jia, R Geoffrey, R Alemzadeh, S … - The Journal of Immunology, 2008 - Am Assoc Immnol
Understanding active proinflammatory mechanisms at and before type 1 diabetes
mellitus (T1DM) onset is hindered in humans, given that the relevant tissues are
inaccessible and pancreatic immune responses are difficult to measure in ...
Cited by 11 - Related articles - All 2 versions

Interferons induce an antiviral state in human pancreatic islet cells


M Hultcrantz, MH Hühn, M Wolf, A Olsson, S … - Virology, 2007 - Elsevier
Enterovirus infections, in particular those with Coxsackieviruses, have been
linked to the development of type 1 diabetes (T1D). Although animal models have
demonstrated that interferons (IFNs) regulate virus-induced T1D by acting ...
Cited by 11 - Related articles - All 3 versions

[CITATION] Autoimmune Polyendocrine Syndromes in Immunology of Type 1 Diabetes


J Barker, GS Eisenbarth - Eienbarth GS, eds, 2003
Cited by 3 - Related articles

[CITATION] Correlations of in vivoß-cell function tests withß-cell mass and pancreatic insulin content …


DK McCulloch, DJ Koerker, SE Kahn… - Diabetes, 1991
Cited by 3 - Related articles

Toll-like receptor 3 and STAT-1 contribute to double-stranded RNA+ interferon-γ-induced …


J Rasschaert, L Ladrière, M Urbain, Z … - Journal of Biological Chemistry, 2005 - ASBMB
Viral infections and local production of cytokines probably contribute to the
pathogenesis of Type 1 diabetes. The viral replicative intermediate
double-stranded RNA (dsRNA, tested in the form of ...
Cited by 41 - Related articles - BL Direct - All 5 versions

HLA-DPB1* 0402 protects against type 1A diabetes autoimmunity in the highest risk …

- shouxi.net
EE Baschal, TA Aly, SR Babu, MS Fernando, L … - Diabetes, 2007 - Am Diabetes Assoc
OBJECTIVE— A major goal in genetic studies of type 1A diabetes is prediction
of anti-islet autoimmunity and subsequent diabetes in the general population, as
>85% of patients do not have a first-degree relative with type 1A diabetes. ...
Cited by 15 - Related articles - BL Direct - All 5 versions


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