WL Suarez-Pinzon, Y Yan, R Power, SJ Brand, A … - Diabetes, 2005 - Am Diabetes Assoc Combination therapy with epidermal growth factor (EGF) and gastrin induces β-cell regeneration
in rodents with chemically induced diabetes. We investigated whether EGF plus gastrin could
correct hyperglycemia in NOD mice with autoimmune diabetes. Combined treatment with ... Cited by 54 - Related articles - BL Direct - All 5 versions
- ►endojournals.org WL Suarez-Pinzon, JRT Lakey, SJ Brand, A … - Journal of Clinical …, 2005 - Endocrine Soc Pancreatic islet transplantation is a viable treatment for type 1 diabetes, but is limited by human
donor tissue availability. The combination of epidermal growth factor (EGF) and gastrin induces
islet ß-cell neogenesis from pancreatic exocrine duct cells in rodents. In this study we ... Cited by 69 - Related articles - All 5 versions
SJ Brand, S Tagerud, P Lambert, SG … - Pharmacology and …, 2002 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 51 - Related articles - BL Direct - All 4 versions
JJ Meier, AE Butler, R Galasso, RA Rizza, PC Butler - Diabetologia, 2006 - Springer Abstract Aims/hypothesis Type 1 and type 2 diabetes are charac- terised by a beta cell
deficit. Islet hyperplasia has been described in patients with Zollinger–Ellison syndrome secondary
to gastrin-producing tumours (gastrinomas), and gastrin therapy has increased beta cell ... Cited by 21 - Related articles - BL Direct - All 5 versions
I Rooman, L Bouwens - Diabetologia, 2004 - Springer Aims/hypothesis. Increasing beta-cell mass and/or function could restore glucose homeostasis
in diabetes mellitus. Hitherto, trophic factors for beta-cell regen- eration after toxic events have
been difficult to identi- fy. We evaluated the application of gastrin and epider- mal growth ... Cited by 64 - Related articles - BL Direct - All 4 versions
JJ Meier, A Bhushan, AE Butler, RA Rizza, PC Butler - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: Type 1 diabetes is widely held to result from an irreversible loss of
insulin-secreting beta cells. However, insulin secretion is detectable in some peo- ple with
long-standing type 1 diabetes, indicating either a small population of surviving beta cells ... Cited by 104 - Related articles - BL Direct - All 5 versions
I Rooman, J Lardon, L Bouwens - Diabetes, 2002 - Am Diabetes Assoc It is still unclear which factors regulate pancreatic regeneration and β-cell neogenesis and which
precursor cells are involved. We evaluated the role of intravenously infused gastrin in regenerating
pancreas of duct-ligated rats. The ligation of exocrine ducts draining the splenic half of the ... Cited by 103 - Related articles - BL Direct - All 4 versions
L Rosenberg, M Lipsett, JW Yoon, M Prentki, R … - Annals of …, 2004 - pubmedcentral.nih.gov From the *Department of Surgery, McGill University, Montreal, Quebec, Canada; †Julia Macfarlane
Diabetes Research Center, University of Calgary, Calgary, Alberta, Canada; the ‡Departments
of Nutrition and Biochemistry, University of Montreal, Montreal, Quebec, Canada; and § ... Cited by 58 - Related articles - BL Direct - All 4 versions
WL Suarez-Pinzon, RF Power, Y Yan, C Wasserfall, M … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Combination therapy with GLP-1 and gastrin, but not with GLP-1 or gastrin
alone, restored normoglycemia in diabetic NOD mice. The GLP-1 and gastrin combination increased
pancreatic insulin content, β-cell mass, and insulin-positive cells in pancreatic ducts, and ... Cited by 5 - Related articles - All 3 versions
Y Fujinaka, D Sipula, A Garcia-Ocaña, RC Vasavada - Diabetes, 2004 - Am Diabetes Assoc Transgenic overexpression of either parathyroid hormone-related peptide (PTHrP) or mouse
placental lactogen type 1 (mPL1) in pancreatic β-cells, using the rat insulin II promoter (RIP),
results in islet hyperplasia either through prolonged β-cell survival or through increased β- ... Cited by 28 - Related articles - BL Direct - All 5 versions
