- ►diabetesjournals.org WH Kim, JW Lee, YH Suh, SH Hong, JS Choi, … - Diabetes, 2005 - Am Diabetes Assoc Chronic hyperglycemia is toxic to pancreatic ß-cells, impairing cellular
functioning as observed in type 2 diabetes; however, the mechanism underlying
ß-cell dysfunction and the resulting apoptosis via glucose toxicity are ... Cited by 39 - Related articles - BL Direct - All 9 versions
- ►ncl.ac.uk [PDF] C Arden, S Baltrusch, L Agius - FEBS letters, 2006 - Elsevier The association of glucokinase with liver mitochondria has been reported [Danial
et al. (2003) BAD and glucokinase reside in a mitochondrial complex that
integrates glycolysis and apoptosis. Nature 424, 952–956]. We confirmed ... Cited by 10 - Related articles - All 12 versions
C Arden, A Harbottle, S Baltrusch, M Tiedge, … - Diabetes, 2004 - Am Diabetes Assoc The association of glucokinase with insulin secretory granules has been shown by
cell microscopy techniques. We used MIN6 insulin-secretory cells and organelle
fractionation to determine the effects of glucose on the subcellular ... Cited by 27 - Related articles - BL Direct - All 4 versions
[CITATION] ves-Guerra MC, Goubern M, Surwit R, Bouillaud F, Richard D, Collins S, Ricquier D: …
C Vanhoutte, A Sener, WJ Malaisse - Molecular and cellular biochemistry, 1997 - Springer It was recently proposed that stimulation of pancreatic islet by D-glucose
results in the translocation of glucokinase from the perinuclear area to the
cell periphery, where the enzyme might conceivably interact with either the ... Cited by 6 - Related articles - BL Direct - All 5 versions
D Tsakiris, K Ioannou - Journal of nephrology - ncbi.nlm.nih.gov Maturity onset diabetes of the young (MODY syndrome) is characterized by a
non-ketotic type II diabetes mellitus (DM) that is inherited by an autosomal
dominant mode and appears in young people, <25 yrs old, with a prominent ... Cited by 7 - Related articles - BL Direct - All 5 versions
AV Kuznetsov, S Schneeberger, O Renz, H … - Transplantation, 2004 - journals.lww.com Background. Mitochondria play a critical role in ischemia-reperfusion injury of
the heart. The purpose of the present study was to analyze the intracellular
region-specific functional state of mitochondria after cold ... Cited by 9 - Related articles - BL Direct - All 4 versions
Y Takeda, MA Pérez-Pinzón, MD Ginsberg, TJ … - Journal of Cerebral Blood Flow & Metabolism, 2004 - nature.com The direction of the chemical reaction of ATP synthetase is reversible. The
present study was designed to determine whether mitochondria produce or consume
ATP during ischemia. For this purpose, changes in mitochondrial membrane ... Cited by 9 - Related articles - BL Direct - All 7 versions
DH Margineantu, RM Brown, GK Brown, AH … - Mitochondrion, 2002 - Elsevier A fusion protein between GFP and the E1α subunit of the pyruvate dehydrogenase
(PDH) complex was created and shown to assemble into functional PDH complexes
using immunoprecipitation and activity assays. The expression of this ... Cited by 16 - Related articles - All 3 versions
- ►nih.gov I Quesada, MG Todorova, B Soria - Biophysical journal, 2006 - Elsevier Blood glucose homeostasis is mainly achieved by the coordinated function of
pancreatic α-, β-, and δ-cells, which secrete glucagon, insulin, and
somatostatin, respectively. Each cell type responds to glucose changes with ... Cited by 18 - Related articles - BL Direct - All 7 versions
