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Scholar Results 1 - 10 of about 101 related to Harris: Type 2 Diabetes Causes Remodeling of Cerebrovasculature via Differential Regulation.... (0.11 sec) 

Type 2 Diabetes Causes Remodeling of Cerebrovasculature via Differential Regulation of …

- shouxi.net
AK Harris, JR Hutchinson, K Sachidanandam … - Diabetes, 2005 - Am Diabetes Assoc
The risk of cerebrovascular disease is four- to sixfold higher in patients with
diabetes. Vascular remodeling, characterized by extracellular matrix deposition
and an increased media-to-lumen ratio, occurs in diabetes and contributes ...
Cited by 29 - Related articles - BL Direct - All 5 versions

Evidence for vasculoprotective effects of ETB receptors in resistance artery remodeling in …

- diabetesjournals.org
K Sachidanandam, V Portik-Dobos, AK Harris, … - Diabetes, 2007 - Am Diabetes Assoc
OBJECTIVE—Vascular remodeling, characterized by extracellular matrix
deposition and increased media-to-lumen (M/l) ratio, contributes to the
development of microvascular complications in diabetes. Matrix ...
Cited by 8 - Related articles - BL Direct - All 6 versions

Differential effects of ETA and ETB receptor antagonism on oxidative stress in type 2 …


MM Elgebaly, V Portik-Dobos, K … - Vascular pharmacology, 2007 - Elsevier
Endothelin (ET-1) is chronically elevated in diabetes. However, role of ET-1 in
increased oxidative stress in type 2 diabetes is less clear. This study tested
the hypotheses that: 1) oxidative stress markers are increased and total ...
Cited by 6 - Related articles - All 3 versions

Impaired insulin-mediated vasorelaxation in a nonobese model of type 2 diabetes: role of …


MM Elgebaly, A Kelly, AK Harris, H Elewa, V … - Canadian Journal of Physiology and Pharmacology, 2008 - ingentaconnect.com
Abstract: Insulin resistance involves decreased phosphorylation of insulin
receptor substrate (IRS) proteins and (or) Akt. In the vasculature, modulated
Akt phosphorylation may cause impaired vasorelaxation via decreased eNOS ...
Cited by 5 - Related articles - All 6 versions

Effect of chronic endothelin receptor antagonism on cerebrovascular function in type 2 …

- physiology.org
AK Harris, MM Elgebaly, W Li, K … - … Journal of Physiology- Regulatory, Integrative and …, 2008 - Am Physiological Soc
Diabetes increases the risk of stroke and contributes to poor clinical outcomes
in this patient population. Myogenic tone of the cerebral vasculature, including
basilar arteries, plays a key role in controlling cerebral blood flow. ...
Cited by 7 - Related articles - BL Direct - All 4 versions

Type-2 diabetes-induced changes in vascular extracellular matrix gene expression: relation …


WW Song, A Ergul - Cardiovascular Diabetology, 2006 - cardiab.com
Hyperglycemia-induced changes in vascular wall structure contribute to the
pathogenesis of diabetic microvascular and macrovascular complications. Matrix
metalloproteinases (MMP), a family of proteolytic enzymes that degrade ...
Cited by 15 - Related articles - Cached - All 10 versions

Insulin-induced Activation of Atypical Protein Kinase C, but Not Protein Kinase B, Is …


ML Standaert, MP Sajan, A Miura, Y Kanoh, … - Journal of Biological Chemistry, 2004 - ASBMB
Insulin resistance in type 2 diabetes is characterized by defects in muscle
glucose uptake and hepatic overproduction of both glucose and lipids. These
hepatic defects are perplexing because insulin normally suppresses glucose ...
Cited by 31 - Related articles - BL Direct - All 4 versions

Stress upregulates arterial matrix metalloproteinase expression and activity via endothelin A …


A Ergul, V Portik-Dobos, AD Giulumian, MM … - AJP-Heart and Circulatory Physiology, 2003 - ajpheart.physiology.org.p.angrylapdog.com
Degradation of the extracellular matrix proteins by matrix metalloproteinases
(MMP) is an important regulatory step in the vascular remodeling process. Recent
studies demonstrated that ET A receptors regulate cardiac MMP activity and ...
Cited by 35 - Related articles - BL Direct - All 5 versions

Endothelin-mediated remodeling in aortas of diabetic rats


G Fukuda, ZA Khan, YP Barbin, H … - Diabetes/Metabolism Reviews - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 15 - Related articles - All 3 versions

Effect of chronic and selective endothelin receptor antagonism on microvascular function in …

- physiology.org
K Sachidanandam, MM Elgebaly, AK Harris, JR … - American Journal of Physiology- Heart and Circulatory …, 2008 - Am Physiological Soc
Vascular dysfunction, which presents either as an increased response to
vasoconstrictors or an impaired relaxation to dilator agents, results in
worsened cardiovascular outcomes in diabetes. We have established that the ...
Cited by 4 - Related articles - All 3 versions


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