- ►shouxi.net D Bach, D Naon, S Pich, FX Soriano, N Vega, J … - Diabetes, 2005 - Am Diabetes Assoc The primary gene mutated in Charcot-Marie-Tooth type 2A is mitofusin-2 (Mfn2).
Mfn2 encodes a mitochondrial protein that participates in the maintenance of the
mitochondrial network and that regulates mitochondrial metabolism and ... Cited by 41 - Related articles - BL Direct - All 5 versions
G Mingrone, M Manco, M Calvani, M … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: In obesity the cellular capac- ity to switch from
using lipid to carbohydrate and vice versa as the energy substrate, known as
'metabolic flexibility', is impaired. Mitofusin 2 (MFN2), a mitochon- drial ... Cited by 17 - Related articles - BL Direct - All 4 versions
- ►oxfordjournals.org S Pich, D Bach, P Briones, M Liesa, M Camps, … - Human molecular genetics, 2005 - Oxford Univ Press Mitofusin-2 (Mfn2) is a mitochondrial membrane protein that participates in
mitochondrial fusion in mammalian cells and mutations in the Mfn2 gene cause
Charcot–Marie–Tooth neuropathy type 2A. Here, we show that Mfn2 loss-of- ... Cited by 68 - Related articles - All 7 versions
- ►nih.gov R Cartoni, B Leger, MB Hock, M Praz, A … - The Journal of Physiology, 2005 - Physiological Soc Mitochondrial impairment is hypothesized to contribute to the pathogenesis of
insulin resistance. Mitofusin (Mfn) proteins regulate the biogenesis and
maintenance of the mitochondrial network, and when inactivated, cause a ... Cited by 63 - Related articles - BL Direct - All 9 versions
D Bach, S Pich, FX Soriano, N Vega, B … - Journal of Biological Chemistry, 2003 - ASBMB In many cells and specially in muscle, mitochondria form elongated filaments or
a branched reticulum. We show that Mfn2 (mitofusin 2), a mitochondrial membrane
protein that participates in mitochondrial fusion in mammalian cells, is ... Cited by 147 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org FX Soriano, M Liesa, D Bach, DC Chan, M … - Diabetes, 2006 - Am Diabetes Assoc Mitofusin 2 (Mfn2) is a mitochondrial membrane protein that participates in
mitochondrial fusion and regulates mitochondrial metabolism in mammalian cells.
Here, we show that Mfn2 gene expression is induced in skeletal muscle and ... Cited by 36 - Related articles - BL Direct - All 4 versions
KH Chen, X Guo, D Ma, Y Guo, Q Li, D Yang, P … - Nature cell biology, 2004 - cmbi.bjmu.edu.cn Vascular proliferative disorders, such as atherosclerosis and restenosis, are
the most common causes of severe cardiovascular diseases, but a common molecular
mechanism remains elusive. Here, we identify and characterize a novel ... Cited by 93 - Related articles - BL Direct - All 10 versions
- ►biologists.org A Santel, S Frank, B Gaume, M Herrler, RJ … - Journal of cell science, 2003 - jcs.biologists.org Mitochondrial fusion may regulate mitochondrial morphogenesis and underlie
complementation between mitochondrial genomes in mammalian cells. The nuclear
encoded mitochondrial proteins Mfn1 and Mfn2 are human homologues of the ... Cited by 78 - Related articles - BL Direct - All 6 versions
G Gastaldi, A Russell, A Golay, JP Giacobino, … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis We investigated whether skeletal muscle per- oxisome
proliferator-activated receptor gamma coactivator-1 (PGC1A; also known as
PPARGC1A) and its target mitofusin-2 (MFN2), as well as carnitine ... Cited by 7 - Related articles - BL Direct - All 2 versions
H Moreno, AL Serrano, T Santalucia, A Guma, … - Journal of Biological Chemistry, 2003 - ASBMB We have reported a novel functional co-operation among MyoD, myocyte enhancer
factor-2 (MEF2), and the thyroid hormone receptor in a muscle-specific enhancer
of the rat GLUT4 gene in muscle cells. Here, we demonstrate that the muscle- ... Cited by 19 - Related articles - BL Direct - All 4 versions
