- ►diabetesjournals.org N Kaiser, R Nesher, MY Donath, M Fraenkel, V … - Diabetes, 2005 - Am Diabetes Assoc Type 2 diabetes is characterized by insulin resistance and progressive ß-cell
failure. Deficient insulin secretion, with increased proportions of insulin
precursor molecules, is a common feature of type 2 diabetes; this could ... Cited by 26 - Related articles - BL Direct - All 6 versions
N Kaiser, M Yuli, G Üçkaya, AI Oprescu, MF … - Diabetes, 2005 - Am Diabetes Assoc Recent studies ascribe a major role to pancreatic β-cell loss in type 2
diabetes. We investigated the dynamics of β-cell mass during diabetes evolution
in Psammomys obesus, a model for nutrition-dependent type 2 diabetes, ... Cited by 21 - Related articles - All 7 versions
V Attali, M Parnes, Y Ariav, E Cerasi, N Kaiser … - Endocrinology, 2006 - Endocrine Soc Succinate stimulates insulin secretion and proinsulin biosynthesis. We studied
the effects of reduced nicotinamide adenine dinucleotide phosphate
(NADPH)-modulating pathways on glucose- and succinate-stimulated insulin ... Cited by 5 - Related articles - BL Direct - All 4 versions
E Shafrir, E Ziv, R Kalman - ILAR JOURNAL, 2006 - dels.nas.edu The dietary effects of hyperglycemia increasingly result in type 2 diabetes in
humans. Two species, the spiny mice (Acomys cahirinus) and the desert gerbil
(Psammomys obe- sus), which have different metabolic responses to such ef- ... Cited by 13 - Related articles - View as HTML - BL Direct - All 3 versions
K Edstrom, E Cerasi, R Luft - Acta Endocrinologica, 1974 - EFES During pregnancy, the insulin response of the low responders was enhanced as in
the controls, but at all stages the insulin response was significantly less than
in the controls. None of the subjects developed glucose intolerance during ... Cited by 10 - Related articles - All 5 versions
- ►diabetesjournals.org M Fraenkel, M Ketzinel-Gilad, Y Ariav, O … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Unexpectedly, rapamycin worsened hyperglycemia in diabetic P. obesus
without affecting glycemia in normoglycemic controls. There was a 10-fold
increase of serum insulin in diabetic P. obesus compared with controls; ... Cited by 20 - Related articles - BL Direct - All 4 versions
- ►endojournals.org AH Minn, H Lan, ME Rabaglia, DM Harlan, BA … - Molecular Endocrinology, 2005 - Endocrine Soc Type 2 diabetes occurs when pancreatic ß-cells become unable to compensate for
the underlying insulin resistance. Insulin secretion requires ß-cell insulin
stores to be replenished by insulin biosynthesis, which is mainly regulated ... Cited by 16 - Related articles - All 8 versions
M Gadot, G Leibowitz, E Shafrir, E Cerasi, DJ … - Endocrinology, 1994 - Endocrine Soc Page 1. 0013.7227/94/1352-0610$03.00/0 Endocrinology Copyright 0 1994 by The Endocrine
Society Vol. 135, No. 2 Printed in USA Hyperproinsulinemia ... Cited by 40 - Related articles - BL Direct - All 3 versions
- ►endojournals.org GW Van Citters, M Kabir, SP Kim, SD … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc We previously developed a canine model of central obesity and insulin resistance
by supplementing the normal chow diet with 2 g cooked bacon grease/kg body
weight. Dogs fed this fatty diet maintained glucose tolerance with ... Cited by 19 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org TL Jetton, J Lausier, K LaRock, WE Trotman, … - Diabetes, 2005 - Am Diabetes Assoc The physiological mechanisms underlying the compensatory growth of β-cell mass
in insulin-resistant states are poorly understood. Using the insulin-resistant
Zucker fatty (fa/fa) (ZF) rat and the corresponding Zucker lean control ... Cited by 42 - Related articles - BL Direct - All 4 versions
