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Natural history of β-cell function in type 1 diabetes

- diabetesjournals.org
NA Sherry, EB Tsai, KC Herold - Diabetes, 2005 - Am Diabetes Assoc
Despite extensive and ongoing investigations of the immune mechanisms of autoimmune diabetes
in humans and animal models, there is much less information about the natural history of insulin
secretion before and after the clinical presentation of type 1 diabetes and the factors that ...
Cited by 37 - Related articles - BL Direct - All 6 versions

Insulin secretion in type 1 diabetes


C Steele, WA Hagopian, S Gitelman, U Masharani, M … - Diabetes, 2004 - Am Diabetes Assoc
Type 1 diabetes, a chronic autoimmune disease, causes destruction of insulin-producing β-cells
over a period of years. Although many markers of the autoimmune process have been
described, none can convincingly predict the rate of disease progression. Moreover, there ...
Cited by 54 - Related articles - BL Direct - All 4 versions

Markers of beta cell function in type 1 diabetes mellitus.


F Vendrame, A Zappaterreno, F Dotta - Minerva medica, 2004 - ncbi.nlm.nih.gov
Type 1 diabetes mellitus is a multifactorial autoimmune disease characterized by destruction
of insulin producing pancreatic beta cells that results in insulin deficiency and fasting
hyperglycemia. It is now well known that the clinical onset of the disease represents the ...
Cited by 7 - Related articles - BL Direct - All 2 versions

The rise and fall of insulin secretion in type 1 diabetes mellitus


EB Tsai, NA Sherry, JP Palmer, KC Herold - Diabetologia, 2006 - Springer
Abstract An understanding of the natural history of beta cell responses is an essential prerequisite
for interventional studies designed to prevent or treat type 1 diabetes. Here we review published
data on changes in insulin responses in humans with type 1 diabetes. We also describe a ...
Cited by 33 - Related articles - BL Direct - All 3 versions

Characteristics of childhood and adult-onset type 1 diabetes in a multi-ethnic …


M Rodacki, L Zajdenverg, RP Tortora, FA Reis, MS … - Diabetes research and …, 2005 - Elsevier
The study population comprised 52 women and 31 men, 52 white and 31 non-white individuals
with mean age of 29.94 (±10.95) years and mean disease duration of 10.37 (±7.37) years. The
mean age at onset in groups 1 and 2 were, respectively, 11.48 and 27.2 years old. There ...
Cited by 9 - Related articles - All 8 versions

Homogeneity in pattern of decline of beta-cell function in IDDM. Prospective study …


O Snorgaard, LH Lassen, C Binder - Diabetes Care, 1992 - Am Diabetes Assoc
OBJECTIVE--To study the natural history of beta-cell function from onset of IDDM to expected
deterioration of insulin (C-peptide) secretion and to identify different patterns of decline, if
any. RESEARCH DESIGN AND METHODS--A cohort of 204 consecutive newly ...
Cited by 19 - Related articles - All 6 versions

Preservation of C-peptide secretion in subjects at high risk of developing type 1 …


D Schatz, D Cuthbertson, M Atkinson, MC … - Pediatric …, 2004 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ...
Cited by 16 - Related articles - BL Direct - All 3 versions

[CITATION] Demonstration of islet cell function in patients with 50 years or longer of diabetes


HA Keenan, A Berger, JK Sun, G Eisenbarth, A Doria, … - Diabetes, 2007
Cited by 4 - Related articles

Patterns of metabolic progression to type 1 diabetes in the Diabetes Prevention …


JM Sosenko, JP Palmer, CJ Greenbaum, J Mahon, … - Diabetes Care, 2006 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—Fifty-four DPT-1 participants (22 in the parenteral trial
and 32 in the oral trial) were studied. All had oral glucose tolerance tests (OGTTs) at 6-month
intervals from approximately 30 to 6 months before diagnosis. The vast majority also had ...
Cited by 40 - Related articles - BL Direct - All 5 versions

Relationship between the prevalence of anti-glutamic acid decarboxylase …


M Rodacki, L Zajdenverg, MS Albernaz, MR … - Brazilian Journal of …, 2004 - SciELO Brasil
The objective of the present study was to determine whether the duration of disease has any
influence on the prevalence of glutamic acid decarboxylase autoantibodies (GADA) in Brazilian
patients with type 1 diabetes (T1D) and variable disease duration. We evaluated 83 ...
Cited by 6 - Related articles - Cached - BL Direct - All 10 versions


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