A Kubosaki, S Nakamura, AL Notkins - Diabetes, 2005 - Am Diabetes Assoc IA-2 and IA-2β are members of the transmembrane protein tyrosine phosphatase
family located in dense core vesicles of neuroendocrine cells, including the
β-cells of pancreatic islets. In the present study, by mating C57BL/6Nci ... Cited by 12 - Related articles - BL Direct - All 5 versions
- ►endojournals.org A Kubosaki, S Nakamura, A Clark, JF Morris, … - Endocrinology, 2006 - Endocrine Soc Female infertility is a worldwide problem affecting 10–15% of the population.
The cause of the infertility in many cases is not known. In the present report,
we demonstrate that alterations in two transmembrane structural proteins, ... Cited by 10 - Related articles - BL Direct - All 5 versions
A Kubosaki, S Gross, J Miura, K Saeki, M Zhu … - Diabetes, 2004 - Am Diabetes Assoc Insulinoma-associated protein (IA)-2β, also known as phogrin, is an
enzymatically inactive member of the transmembrane protein tyrosine phosphatase
family and is located in dense-core secretory vesicles. In patients with ... Cited by 26 - Related articles - BL Direct - All 8 versions
- ►nih.gov S Harashima, A Clark, MR Christie, AL … - Proceedings of the National Academy of Sciences, 2005 - National Acad Sciences IA-2 is an enzymatically inactive member of the transmembrane protein tyrosine
phosphate family located in dense core secretory vesicles and a major
autoantigen in type 1 diabetes. Recent studies showed that targeted ... Cited by 27 - Related articles - All 9 versions
A Kubosaki, S Nakamura, AL Notkins - 糖尿病学杂志, 2005 - journal.shouxi.net IA-2 and IA-2 are members of the transmembrane protein tyrosine phosphatase
family located in dense core vesicles of neuroendocrine cells, including the
-cells of pancreatic islets. In the present study, by mating C57BL/6Nci ... Related articles - Cached
- ►endocrinology-journals.org JC Henquin, M Nenquin, A Szollosi, A … - Journal of Endocrinology, 2008 - Soc Endocrinology Islet antigen-2 (IA-2 or ICA 512) and IA-2β (or phogrin) are major autoantigens
in type 1 diabetes. They are located in dense core secretory vesicles including
insulin granules, but their role in β-cell function is unclear. Targeted ... Cited by 3 - Related articles - BL Direct - All 2 versions
T Nishimura, A Kubosaki, Y Ito, AL Notkins - Neuroscience, 2009 - Elsevier Islet-associated protein 2 (IA-2) and IA-2β are major autoantigens in type 1
diabetes and transmembrane proteins in dense core secretory vesicles (DCV) of
neuroendocrine cells. The deletion of these genes results in a decrease in ... Cited by 2 - Related articles
- ►diabetesjournals.org K Saeki, M Zhu, A Kubosaki, J Xie, MS Lan, … - Diabetes, 2002 - Am Diabetes Assoc IA-2 is a major autoantigen in type 1 diabetes. Autoantibodies to IA-2 appear
years before the development of clinical disease and are being widely used as
predictive markers to identify individuals at risk for developing type 1 ... Cited by 61 - Related articles - BL Direct - All 4 versions
- ►umich.edu [PDF] YF Hu, HL Zhang, T Cai, S Harashima, AL … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: Islet antigen-2 (IA-2), a major autoantigen in type 1
diabetes, is an enzymatically inactive member of the transmembrane protein
tyrosine phosphatase (PTP) family. IA-2 is located in dense-core secretory ... Cited by 4 - Related articles - BL Direct - All 4 versions
S Shimizu, N Saito, A Kubosaki, S SungWook … - Biochemical and Biophysical Research …, 2001 - Elsevier Islet antigen (IA)-2 is a novel autoantigen of insulin-dependent diabetes
mellitus (IDDM), and belongs to a new class within the receptor-type protein
tyrosine phosphatase (PTP) family characterized by lack of PTP enzymatic ... Cited by 4 - Related articles - BL Direct - All 5 versions