- ►diabetesjournals.org C Pihoker, LK Gilliam, CS Hampe, Å … - Diabetes, 2005 - Am Diabetes Assoc Islet cell autoantibodies are strongly associated with the development of type 1
diabetes. The appearance of autoantibodies to one or several of the
autoantigens—GAD65, IA-2, or insulin—signals an autoimmune pathogenesis ... Cited by 53 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org P Achenbach, E Bonifacio, K Koczwara, AG … - Diabetes, 2005 - Am Diabetes Assoc The natural history of autoimmune type 1 diabetes in children is associated with
the appearance of islet autoantibodies early in life, which is influenced by
genetic and environmental factors. Once islet autoantibodies have ... Cited by 37 - Related articles - BL Direct - All 9 versions
- ►diabetesjournals.org J Graham, WA Hagopian, I Kockum, LS Li, CB … - Diabetes, 2002 - Am Diabetes Assoc Age-dependent associations between type 1 diabetes risk genes HLA, INS VNTR, and
CTLA-4 and autoantibodies to GAD65 (GADAs), ICA512/IA-2, insulin, and islet
cells were determined by logistic regression analysis in 971 incident ... Cited by 72 - Related articles - BL Direct - All 6 versions
MM Jahromi, GS Eisenbarth - Cellular and molecular life sciences, 2007 - Springer Abstract. Type 1A diabetes is an organ-specific auto- immune disease resulting
from destruction of insulin- producing pancreatic b-cells. The main
susceptibility genes code for polymorphic HLA molecules and in particular ... Cited by 21 - Related articles - BL Direct - All 5 versions
GS Eisenbarth - Advances in experimental medicine and biology, 2004 - ncbi.nlm.nih.gov 1: Adv Exp Med Biol. 2004;552:268-90. Prediction of type 1 diabetes: the
natural history of the prediabetic period. Eisenbarth GS. ... Cited by 29 - Related articles - All 2 versions
- ►nih.gov AL Notkins, A Lernmark - Journal of Clinical Investigation, 2001 - Am Soc Clin Investig Type 1 diabetes, also known as either juvenile diabetes (because of the early
age of onset) or insulin-dependent diabetes mellitus (because of the clinical
need for insulin), is now widely thought to be an organ-specific autoimmune ... Cited by 156 - Related articles - BL Direct - All 9 versions
- ►bmjjournals.com MA Kelly, ML Rayner, CH Mijovic, AH Barnett - Molecular Pathology, 2003 - Assoc Clin Pathol Type 1 diabetes is a T cell mediated autoimmune disease, characterised by the
selective destruction of pancreatic ß cells, and susceptibility is determined
by a combination of genetic and environmental factors. The environmental ... Cited by 53 - Related articles - BL Direct - All 8 versions
R Hermann, AP Laine, R Veijola, T Vahlberg, S … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: The aim of this study was to explore the contribution
of genetic factors to the emer- gence of beta-cell-specific humoral
autoimmunity. Subjects and methods: We analysed the effect of HLA class II, ... Cited by 18 - Related articles - BL Direct - All 4 versions
K Larsson, H Elding-Larsson, E Cederwall, K … - Diabetes/Metabolism Reviews - interscience.wiley.com The mechanisms by which gestational infections, blood incompatibility, birth
weight, mother's age and other prenatal or neonatal events increase the risk for
type 1 diabetes are not understood. Studies so far have been retrospective, ... Cited by 20 - Related articles - BL Direct - All 3 versions
MS Kim, C Polychronakos - Horm Res, 2005 - content.karger.com The T-cell mediated autoimmune process that destroys pancreatic cells in type 1
diabetes (T1D) is a complex phenotype influenced by multiple genetic and
environmental factors. Human leukocyte antigen (HLA) accounts for about ... Cited by 25 - Related articles - BL Direct - All 5 versions
