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Scholar Results 1 - 10 of about 101 related to Bottino: Multifaceted therapeutic approaches for a multigenic disease. (0.12 sec) 

Multifaceted therapeutic approaches for a multigenic disease


R Bottino, M Trucco - Diabetes, 2005 - Am Diabetes Assoc
Diabetes is a severe chronic disease that affects ∼200 million individuals
worldwide, with extremely debilitating effects and considerably high health care
costs. The two major classes of diabetes, known as type 1 (previously known ...
Cited by 13 - Related articles - BL Direct - All 6 versions

Glucose tolerance normalization following transplantation of pig pancreatic primordia into …


SA Rogers, F Chen, M Talcott, H Liapis, … - Transplant immunology, 2006 - Elsevier
Pancreas or pancreatic islet transplantation in humans is limited by organ
availability, and success of the latter is negatively impacted upon by tissue
loss post-transplantation and limited potential for expansion of beta ...
Cited by 7 - Related articles - All 4 versions

Effect of long-term culture on the expression of antigens and adhesion molecule in single …


K Edamura, K Nasu, Y Iwami, R Nishimura, … - Xenotransplantation, 2005 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 5 - Related articles - All 3 versions

Long-term engraftment following transplantation of pig pancreatic primordia into non- …


SA Rogers, F Chen, MR Talcott, C Faulkner … - Xenotransplantation, 2007 - interscience.wiley.com
Background: Transplantation therapy for human diabetes is limited by a shortage
of donor organs, and transplant function diminished over time by cell death and
limited potential for expansion of beta cells in pancreas or islets. ...
Cited by 11 - Related articles - BL Direct - All 4 versions

Embryonic pig pancreatic tissue transplantation for the treatment of diabetes


S Eventov-Friedman, D Tchorsh, H Katchman, E … - PLoS Med, 2006 - medicine.plosjournals.org
Implantation of embryonic pig pancreatic tissues of different gestational ages
in SCID mice reveals that embryonic day 42 (E42) pig pancreas can enable a
massive growth of pig islets for prolonged periods and restore ...
Cited by 22 - Related articles - Cached - All 11 versions

Chick embryo pancreatic transplants reverse experimental diabetes of rats.

- nih.gov [PDF] 
R Eloy, K Haffen, M Kedinger, JF Grenier - Journal of Clinical Investigation, 1979 - pubmedcentral.nih.gov
ABSTRACT The effectiveness of xenogeneic em- bryonic tissuein the treatment of
experimental diabetes has been investigated in rats. The splenic lobes (80) of
15- to 18d-old chick embryos, composed almost exclusively ofendocrine ...
Cited by 16 - Related articles - All 4 versions

Normalization of glucose post-transplantation of pig pancreatic anlagen into non- …


SA Rogers, H Liapis, MR Hammerman - Transplant immunology, 2005 - Elsevier
Embryonic day (E) 28 (E28) pig pancreatic anlagen (PPA) transplanted into the
omentum of non-immunosuppresed steptozotocin-diabetic Lewis rats normalize
levels of circulating glucose within 2–4 weeks. Following transplantation ...
Cited by 18 - Related articles - All 3 versions

[CITATION] Non-transmitted maternal HLA DQ2 or DQ8 alleles and risk of Type 1 diabetes in offspring: …


AP Lambert, KM Gillespie, PJ Bingley, EA … - Diabetologia, 2003
Cited by 3 - Related articles

Islet cell engraftment and control of diabetes in rats after transplantation of pig pancreatic …

- physiology.org
SA Rogers, F Chen, M Talcott, MR … - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc
The insufficient supply of tissue, loss posttransplantation, and limited
potential for expansion of -cells restrict the use of islet allotransplantation
for diabetes. A way to overcome the supply and expansion problems is to ...
Cited by 19 - Related articles - BL Direct - All 5 versions

Windows of opportunity for organogenesis


MR Hammerman - Transplant immunology, 2005 - Elsevier
Growing new organs in situ by implanting developing animal organ
anlagen/primordia represents a novel solution to the problem of limited supply
for human donor organs that offers advantages relative to transplanting ...
Cited by 12 - Related articles - All 4 versions


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