- ►diabetesjournals.org M Cnop, N Welsh, JC Jonas, A Jörns, S Lenzen … - Diabetes, 2005 - Am Diabetes Assoc Type 1 and type 2 diabetes are characterized by progressive β-cell failure.
Apoptosis is probably the main form of β-cell death in both forms of the
disease. It has been suggested that the mechanisms leading to nutrient- and ... Cited by 174 - Related articles - BL Direct - All 10 versions
M Cnop, N Welsh, JC Jonas, A Jrns, S Lenzen, … - 糖尿病学杂志, 2005 - journal.shouxi.net Type 1 and type 2 diabetes are characterized by progressive -cell failure.
Apoptosis is probably the main form of -cell death in both forms of the disease.
It has been suggested that the mechanisms leading to nutrient- and cytokine- ... Related articles - Cached
AK Cardozo, F Ortis, J Storling, YM Feng, J … - Diabetes, 2005 - Am Diabetes Assoc Cytokines and free radicals are mediators of β-cell death in type 1 diabetes.
Under in vitro conditions, interleukin-1β (IL-1β) + γ-interferon (IFN-γ)
induce nitric oxide (NO) production and apoptosis in rodent and human ... Cited by 102 - Related articles - All 8 versions
- ►daegu.ac.kr [PDF] DL Eizirik, T Mandrup-Poulsen - Diabetologia, 2001 - Springer Apoptosis is likely to be the main form of beta-cell death in immune-mediated
diabetes mellitus in ro- dents and possibly in humans. Clarification of the
regulation of beta-cell death could indicate novel sites for therapeutic ... Cited by 323 - Related articles - BL Direct - All 6 versions
J Rasschaert, L Ladrière, M Urbain, Z … - Journal of Biological Chemistry, 2005 - ASBMB Viral infections and local production of cytokines probably contribute to the
pathogenesis of Type 1 diabetes. The viral replicative intermediate
double-stranded RNA (dsRNA, tested in the form of ... Cited by 41 - Related articles - BL Direct - All 5 versions
- ►pubget.com [PDF] DR Laybutt, AM Preston, MC Åkerfeldt, JG … - Diabetologia, 2007 - Springer Page 1. ARTICLE Endoplasmic reticulum stress contributes to beta cell apoptosis
in type 2 diabetes DR Laybutt & AM Preston & MC Åkerfeldt & ... Cited by 105 - Related articles - BL Direct - All 5 versions
- ►endojournals.org I Kharroubi, L Ladriere, AK Cardozo, Z … - Endocrinology, 2004 - Endocrine Soc Apoptosis is probably the main form of ß-cell death in both type 1 diabetes
mellitus (T1DM) and T2DM. In T1DM, cytokines contribute to ß-cell destruction
through nuclear factor- B (NF- B) activation. Previous studies suggested ... Cited by 136 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org P Pirot, F Ortis, M Cnop, Y Ma, LM Hendershot … - Diabetes, 2007 - Am Diabetes Assoc Endoplasmic reticulum stress–mediated apoptosis may play an important role in
the destruction of pancreatic β-cells, thus contributing to the development of
type 1 and type 2 diabetes. One of the regulators of endoplasmic reticulum ... Cited by 23 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org N Welsh, M Cnop, I Kharroubi, M Bugliani, R … - Diabetes, 2005 - Am Diabetes Assoc Different degrees of β-cell failure and apoptosis are present in type 1 and
type 2 diabetes. It has been recently suggested that high glucose–induced
β-cell apoptosis in type 2 diabetes shares a final common pathway with ... Cited by 40 - Related articles - BL Direct - All 6 versions
- ►shouxi.net C Huang, C Lin, L Haataja, T Gurlo, AE Butler … - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE—Endoplasmic reticulum (ER) stress–induced apoptosis may be a
common cause of cell attrition in diseases characterized by misfolding and
oligomerisation of amyloidogenic proteins. The islet in type 2 diabetes is ... Cited by 56 - Related articles - BL Direct - All 5 versions
