- ►shouxi.net D Kukidome, T Nishikawa, K Sonoda, K Imoto, … - Diabetes, 2006 - Am Diabetes Assoc We previously proposed that the production of hyperglycemia-induced
mitochondrial reactive oxygen species (mtROS) is a key event in the development
of diabetes complications. The association between the pathogenesis of ... Cited by 83 - Related articles - BL Direct - All 6 versions
K Fujisawa, T Nishikawa, D Kukidome, K … - Biochemical and Biophysical Research …, 2009 - Elsevier Although it has been reported that thiazolidinediones (TZDs) may reduce
cardiovascular events in type 2 diabetic patients, its precise mechanism is
unclear. We previously demonstrated that hyperglycemia-induced production ... Cited by 2 - Related articles - All 2 versions
- ►cardiovascres.org I Valle, A Alvarez-Barrientos, E Arza, S … - Cardiovascular research, 2005 - cardiovascres.org Objective: Mitochondrial production of oxidants contributes to a variety of
pathological conditions including the vascular complications of diabetes,
neurodegenerative diseases, and cellular senescence. We postulated that a ... Cited by 62 - Related articles - All 7 versions
- ►diabetesjournals.org Z Xie, J Zhang, J Wu, B Viollet, MH Zou - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Exposure of HUVECs to high glucose (30 mmol/l) increased superoxide
anions (O 2 · − ) and prostacyclin synthase nitration. In addition,
overexpression of constitutively active AMPK (Ad-CA-AMPK) or the addition ... Cited by 12 - Related articles - All 3 versions
- ►ahajournals.org [PDF] G Ceolotto, A Gallo, I Papparella, L Franco, E … - Arteriosclerosis, Thrombosis, and Vascular Biology, 2007 - Am Heart Assoc Kluwer Health, 351 West Camden Street, Baltimore, MD 21202-2436. Phone:
410-528-4050. Permissions: Permissions & Rights Desk, Lippincott Williams &
Wilkins, a division of Wolters ... Mediated by NAD(P)H Oxidase via Cited by 29 - Related articles - All 7 versions
- ►ahajournals.org WJ Lee, IK Lee, HS Kim, YM Kim, EH Koh, JC … - Arteriosclerosis, thrombosis, and vascular biology, 2005 - Am Heart Assoc From the Department of Internal Medicine (WJL, EHK, JCW, SMH, M.-SK, SWP, K.-UL,
J.-YP), Asan Institute for Life Sciences (HSK, YMK), University of Ulsan College
of Medicine, Seoul, Republic of Korea; the Department of Internal Medicine ... Cited by 49 - Related articles - All 7 versions
- ►ahajournals.org N Ouchi, R Shibata, K Walsh - Circulation research, 2005 - Am Heart Assoc AMP-activated protein kinase (AMPK) is regulated by various cellular stresses.
Vascular endothelial growth factor (VEGF), a key regulator of angiogenesis, is
also upregulated by several stress-inducible factors such as hypoxia and ... Cited by 44 - Related articles - All 7 versions
- ►ahajournals.org E Schulz, E Anter, MH Zou, JF Keaney Jr - Circulation, 2005 - Am Heart Assoc Methods and Results— Porcine aortic endothelial cells exhibited time- and
concentration-dependent AMPK activation as determined by phosphorylation of AMPK
and its downstream target acetyl coenzyme A carboxylase in response to ... Cited by 55 - Related articles - All 10 versions
- ►diabetesjournals.org BJ Davis, Z Xie, B Viollet, MH Zou - Diabetes, 2006 - Am Diabetes Assoc Metformin, one of most commonly used drugs for the treatment of type 2 diabetes,
improves vascular endothelial functions and reduces cardiovascular events in
patients with type 2 diabetes, although its mechanisms remain unknown. The ... Cited by 93 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org R Ouedraogo, X Wu, SQ Xu, L Fuchsel, H … - Diabetes, 2006 - Am Diabetes Assoc Adiponectin is an abundant adipocyte-derived plasma protein with
antiatherosclerotic effects. Vascular signal transduction by adiponectin is
poorly understood and may involve 5′-AMP–activated protein kinase ... Cited by 56 - Related articles - BL Direct - All 6 versions
