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Scholar Results 1 - 10 of about 101 related to Otonkoski: Noninvasive diagnosis of focal hyperinsulinism of infancy with [18F]-DOPA positron.... (0.11 sec) 

Noninvasive diagnosis of focal hyperinsulinism of infancy with [18F]-DOPA positron …


T Otonkoski, K Näntö-Salonen, M Seppänen, … - Diabetes, 2006 - Am Diabetes Assoc
Congenital hyperinsulinism of infancy (CHI) is characterized by severe
hypoglycemia due to dysregulated insulin secretion, associated with either focal
or diffuse pathology of the endocrine pancreas. The focal condition is ...
Cited by 77 - Related articles - BL Direct - All 7 versions

Characterization of hyperinsulinism in infancy assessed with PET and 18F-fluoro-L-DOPA

- snmjournals.org
MJ Ribeiro, P De Lonlay, T Delzescaux, N … - Journal of Nuclear Medicine, 2005 - Soc Nuclear Med
Hyperinsulinism (HI) of infancy is a neuroendocrine disease secondary to either
focal adenomatous hyperplasia or a diffuse abnormality of insulin secretion of
the pancreas. HI with focal lesions can revert by selective surgical ...
Cited by 78 - Related articles - All 3 versions

Congenital hyperinsulinism: pancreatic [18F] fluoro-L-dihydroxyphenylalanine (DOPA) …

- endojournals.org
P de Lonlay, A Simon-Carre, MJ Ribeiro, N … - Journal of Clinical Endocrinology & Metabolism, 2006 - Endocrine Soc
Results: Immunohistochemical detection of DOPA decarboxylase showed diffuse
staining of Langerhans islets in the whole pancreas in all diffuse cases, in
contrast with dense focal staining in all focal cases. Staining of ...
Cited by 29 - Related articles - BL Direct - All 3 versions

Diagnosis and localization of focal congenital hyperinsulinism by 18F-fluorodopa PET scan


OT Hardy, M Hernandez-Pampaloni, JR Saffer, … - The Journal of Pediatrics, 2007 - Elsevier
The diagnosis of focal or diffuse hyperinsulinism was correct in 23 of the 24
cases (96%) and equivocal in 1 case. [ 18 F]-DOPA PET identified focal areas of
high uptake of radiopharmaceutical in 11 patients. Pathology results ...
Cited by 45 - Related articles - All 14 versions

Preoperative evaluation of infants with focal or diffuse congenital hyperinsulinism by …

- endojournals.org
CA Stanley, PS Thornton, A Ganguly, C … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc
INFANTS WITH CONGENITAL hyperinsulinism frequently present in the neonatal
period with symptomatic hypoglycemia, which may cause seizures or permanent
brain damage. In the past, these infants were believed to have a ...
Cited by 58 - Related articles - BL Direct - All 4 versions

The diagnosis of ectopic focal hyperinsulinism of infancy with [18F]-dopa positron emission …

- endojournals.org
K Hussain, M Seppanen, K Nanto-Salonen, NS … - Journal of Clinical Endocrinology & Metabolism, 2006 - Endocrine Soc
Background: Congenital hyperinsulinism (CHI) is a cause of severe hypoglycemia
in the neonatal and infancy period. Histologically, there are two subtypes with
diffuse and focal disease. The preoperative differentiation of these two ...
Cited by 23 - Related articles - BL Direct - All 4 versions

Congenital hyperinsulinism: intraoperative biopsy interpretation can direct the extent of …


M Suchi, PS Thornton, NS Adzick, C … - The American journal of surgical pathology, 2004 - journals.lww.com
From the *Department of Pathology and Laboratory Medicine, †Division of
Endocrinology, Department of Pediatrics, and ‡Department of Surgery, The
Childrens' Hospital of Philadelphia and University of Pennsylvania School ...
Cited by 27 - Related articles - BL Direct - All 3 versions

The surgical management of congenital hyperinsulinemic hypoglycemia in infancy


CN Fékété, P De Lonlay, F Jaubert, J Rahier … - Journal of pediatric surgery, 2004 - Elsevier
Congenital hyperinsunlinism (CHI) is characterized by profound hypoglycaemia
caused by inappropriate insulin secretion. CHI is a heterogeneous disorder with
at least 2 histologic lesions and several implicated genes. If CHI is ...
Cited by 36 - Related articles - All 10 versions

Acute insulin responses to calcium and tolbutamide do not differentiate focal from diffuse …

- endojournals.org
I Giurgea, K Laborde, G Touati, C Bellanne- … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc
Congenital hyperinsulinism (CHI) is related to two main histological pancreas
anomalies: focal adenomatous hyperplasia and diffuse ß-cell hypersecretion.
Pharmacological tests to measure acute insulin responses (AIR) to ...
Cited by 33 - Related articles - BL Direct - All 4 versions

Proposal for a standardized protocol for 18F-DOPA-PET (PET/CT) in congenital …


K Mohnike, O Blankenstein, HT Christesen, J … - Horm Res, 2006 - content.karger.com
Congenital hyperinsulinism (CHI) is characterized by severe hypoglycemia related
to inappropriate insulin release. The long-term outcome of infants with CHI is
dependent on an effective prevention of hypoglycemic episodes to avert the ...
Cited by 19 - Related articles - All 6 versions


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