T Otonkoski, K Näntö-Salonen, M Seppänen, … - Diabetes, 2006 - Am Diabetes Assoc Congenital hyperinsulinism of infancy (CHI) is characterized by severe
hypoglycemia due to dysregulated insulin secretion, associated with either focal
or diffuse pathology of the endocrine pancreas. The focal condition is ... Cited by 77 - Related articles - BL Direct - All 7 versions
- ►snmjournals.org MJ Ribeiro, P De Lonlay, T Delzescaux, N … - Journal of Nuclear Medicine, 2005 - Soc Nuclear Med Hyperinsulinism (HI) of infancy is a neuroendocrine disease secondary to either
focal adenomatous hyperplasia or a diffuse abnormality of insulin secretion of
the pancreas. HI with focal lesions can revert by selective surgical ... Cited by 78 - Related articles - All 3 versions
- ►endojournals.org P de Lonlay, A Simon-Carre, MJ Ribeiro, N … - Journal of Clinical Endocrinology & Metabolism, 2006 - Endocrine Soc Results: Immunohistochemical detection of DOPA decarboxylase showed diffuse
staining of Langerhans islets in the whole pancreas in all diffuse cases, in
contrast with dense focal staining in all focal cases. Staining of ... Cited by 29 - Related articles - BL Direct - All 3 versions
OT Hardy, M Hernandez-Pampaloni, JR Saffer, … - The Journal of Pediatrics, 2007 - Elsevier The diagnosis of focal or diffuse hyperinsulinism was correct in 23 of the 24
cases (96%) and equivocal in 1 case. [ 18 F]-DOPA PET identified focal areas of
high uptake of radiopharmaceutical in 11 patients. Pathology results ... Cited by 45 - Related articles - All 14 versions
- ►endojournals.org CA Stanley, PS Thornton, A Ganguly, C … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc INFANTS WITH CONGENITAL hyperinsulinism frequently present in the neonatal
period with symptomatic hypoglycemia, which may cause seizures or permanent
brain damage. In the past, these infants were believed to have a ... Cited by 58 - Related articles - BL Direct - All 4 versions
- ►endojournals.org K Hussain, M Seppanen, K Nanto-Salonen, NS … - Journal of Clinical Endocrinology & Metabolism, 2006 - Endocrine Soc Background: Congenital hyperinsulinism (CHI) is a cause of severe hypoglycemia
in the neonatal and infancy period. Histologically, there are two subtypes with
diffuse and focal disease. The preoperative differentiation of these two ... Cited by 23 - Related articles - BL Direct - All 4 versions
M Suchi, PS Thornton, NS Adzick, C … - The American journal of surgical pathology, 2004 - journals.lww.com From the *Department of Pathology and Laboratory Medicine, †Division of
Endocrinology, Department of Pediatrics, and ‡Department of Surgery, The
Childrens' Hospital of Philadelphia and University of Pennsylvania School ... Cited by 27 - Related articles - BL Direct - All 3 versions
CN Fékété, P De Lonlay, F Jaubert, J Rahier … - Journal of pediatric surgery, 2004 - Elsevier Congenital hyperinsunlinism (CHI) is characterized by profound hypoglycaemia
caused by inappropriate insulin secretion. CHI is a heterogeneous disorder with
at least 2 histologic lesions and several implicated genes. If CHI is ... Cited by 36 - Related articles - All 10 versions
- ►endojournals.org I Giurgea, K Laborde, G Touati, C Bellanne- … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Congenital hyperinsulinism (CHI) is related to two main histological pancreas
anomalies: focal adenomatous hyperplasia and diffuse ß-cell hypersecretion.
Pharmacological tests to measure acute insulin responses (AIR) to ... Cited by 33 - Related articles - BL Direct - All 4 versions
K Mohnike, O Blankenstein, HT Christesen, J … - Horm Res, 2006 - content.karger.com Congenital hyperinsulinism (CHI) is characterized by severe hypoglycemia related
to inappropriate insulin release. The long-term outcome of infants with CHI is
dependent on an effective prevention of hypoglycemic episodes to avert the ... Cited by 19 - Related articles - All 6 versions