- ►angrylapdog.com J Harnaha, J Machen, M Wright, R … - …, 2006 - diabetes.diabetesjournals.org.p. … Dendritic cells can facilitate allograft survival and prevent autoimmunity via direct and indirect
cell-mediated mechanisms. Recent studies demonstrate that immunoregulatory dendritic cells
(iDCs) confer immune hyporesponsiveness in part through CD4 + CD25 + T regulatory ... Cited by 33 - Related articles - BL Direct - All 6 versions
- ►jimmunol.org J Machen, J Harnaha, R Lakomy, A Styche, … - The Journal of …, 2004 - Am Assoc Immnol Phenotypically "immature" dendritic cells (DCs), defined by low cell surface CD40, CD80, and
CD86 can elicit host immune suppression in allotransplantation and autoimmunity. Herein, we
report the most direct means of achieving phenotypic immaturity in NOD bone marrow- ... Cited by 38 - Related articles - BL Direct - All 4 versions
- ►oxfordjournals.org J Yates, F Rovis, P Mitchell, B Afzali, JYS … - International …, 2007 - Jpn Soc Immunol CD4 + CD25 + regulatory T cells (Tregs) have far-reaching immunotherapeutic applications,
the realization of which will require a greater understanding of the factors influencing their function
and phenotype during ex vivo manipulation. In murine models, IL-2 plays an important ... Cited by 32 - Related articles - BL Direct - All 7 versions
B Phillips, K Nylander, J Harnaha, J Machen, R … - Diabetes, 2008 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—Microspheres carrying antisense oligonucleotides to
CD40, CD80, and CD86 were delivered into NOD mice. Glycemia was monitored to determine
disease prevention and reversal. In recipients that remained and/or became diabetes ... Cited by 9 - Related articles - All 11 versions
- ►jimmunol.org HJPM Koenen, E Fasse, I Joosten - The Journal of Immunology, 2003 - Am Assoc Immnol An important prerequisite in using regulatory T cells for immunotherapy is their ex vivo expansion
without loss of suppressor function. Human anergic regulatory T cells are expandable by
Ag-specific stimulation in the presence of IL-2. IL-15, like IL-2, is a T cell growth factor that, ... Cited by 55 - Related articles - BL Direct - All 4 versions
A Scheffold, J Huhn, T Hofer - Eur. J. Immunol, 2005 - interscience.wiley.com Although CD4 + CD25 + regulatory T cells (Treg) represent a well-characterized population of
T cells with in vitro and in vivo suppressive capacity, the basic mechanisms of suppression are
still not understood. The constitutive expression of the high-affinity receptor for IL-2 has ... Cited by 62 - Related articles - All 3 versions
[CITATION] Interleukin-7 is a survival factor for CD41 CD251 T-cells and is expressed by …
D Elias, A Avron, M Tamir, I Raz - ANNALS-NEW YORK …, 2006 - interscience.wiley.com Abstract: DiaPep277 is an immunomodulatory peptide that arrests β cell destruction in mouse
models of type 1 diabetes mellitus (T1DM). This article extends an original pilot observation to
two studies of 61 patients (age > 16 years), diagnosed with T1DM within 6 months, and ... Cited by 4 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org PJ Staton, AB Carpenter, SH Jackman - The Journal of Immunology, 2006 - Am Assoc Immnol In a murine model of autoimmunity targeted against the epidermal cell Ags, Skn, adoptive transfer
of Skn-immune T cells to immunosuppressed recipients elicits skin lesions in areas of mild epidermal
trauma. In this study, we examined peripheral regulation of Skn-induced autoreactivity ... Cited by 3 - Related articles - BL Direct - All 4 versions
WJ Leonard - Arthritis Res Ther, 2004 - biomedcentral.com Rheumatoid arthritis (RA) is one of the most common human autoimmune diseases, with a prevalence
of about 1%. Because of this high prevalence as well as the severely debilitating nature of the
disease, considerable efforts have been devoted to the treatment of RA. In the current ... Cited by 4 - Related articles - View as HTML - All 7 versions
