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Scholar Results 1 - 10 of about 101 related to Lee: Novel Leptin Receptor Mutation in NOD/LtJ Mice Suppresses Type 1 Diabetes Progression. (0.08 sec) 

Novel Leptin Receptor Mutation in NOD/LtJ Mice Suppresses Type 1 Diabetes …

- diabetesjournals.org
CH Lee, YG Chen, J Chen, PC Reifsnyder, DV Serreze, … - Diabetes, 2006 - Am Diabetes Assoc
Recently, we identified in normally type 1 diabetes–prone NOD/LtJ mice a spontaneous new
leptin receptor (LEPR) mutation (designated Lepr db-5J ) producing juvenile obesity,
hyperglycemia, hyperinsulinemia, and hyperleptinemia. This early type 2 diabetes ...
Cited by 13 - Related articles - BL Direct - All 7 versions

[CITATION] Immunopathological influence of the Ay, db, ob and nu genes placed on the inbred …


M Nishimura, H Miyamoto - J Immunogenet, 1987 - interscience.wiley.com
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Cited by 6 - Related articles - All 3 versions

Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes …


C Lee, PC Reifsnyder, JK Naggert, C … - DIABETES-NEW …, 2005 - 万方数据资源系统
A spontaneous single-base mutation in the leptin receptor of type 1 diabetes-prone NOD/LtJ
mice (designated as Lepr(db-5J)) produced a glycine640valine transversion in the extracellular
domain. All mutant mice became obese and hyperinsulinemic at weaning, with 70-80% ...
Cited by 11 - Related articles - BL Direct - All 3 versions

Leptin neutralization interferes with pathogenic T cell autoreactivity in autoimmune …

- nih.gov [PDF] 
V De Rosa, C Procaccini, A La Cava, P … - Journal of Clinical …, 2006 - Am Soc Clin Investig
Recent evidence has indicated that leptin, an adipocyte-secreted hormone belonging to the helical
cytokine family, significantly influences immune and autoimmune responses. We investigate
here the mechanisms by which in vivo abrogation of leptin effects protects SJL/J mice ...
Cited by 35 - Related articles - BL Direct - All 10 versions

Serum Leptin Levels and their Relationship to Tumor Necrosis Factoralpha and …


E Koc, G Ustundag, D Aliefendioglu, E … - JOURNAL OF …, 2003 - 万方数据资源系统
Circulating leptin concentrations are raised in animal models of inflammation and sepsis and
leptin production is also increased in rodents by administration of endotoxin or cytokines. The
purpose of this study was to investigate the effect of sepsison serum leptin concentration ...
Cited by 11 - Related articles - BL Direct - All 3 versions

[CITATION] Decreased CD41 lymphocyte activation and increased interleukin-4 production in …


DA Fraser, J Thoen, JE Reseland, O Forre, J Kjeldsen- … - Clin Rheumatol, 1999
Cited by 3 - Related articles

[CITATION] SNP detection on LHB gene and association analysis with litter size in pigs


G Muñoz, A Fernández, C Barragán, L Silió, C Óvilo, C … - Proc. 56th Annu. Meet. Eur. …, 2005
Cited by 3 - Related articles

Leptin-deficient mice are protected from accelerated nephrotoxic nephritis

- amjpathol.org
RM Tarzi, HT Cook, I Jackson, CD Pusey, GM Lord - American Journal of …, 2004 - ASIP
Most forms of glomerulonephritis are immunologically mediated. Accelerated nephrotoxic nephritis
is a model of immune complex glomerulonephritis, in which an immune response is raised to
foreign anti-glomerular basement membrane antibody deposited in the glomerulus. This ...
Cited by 23 - Related articles - BL Direct - All 5 versions

The opposite-direction modulation of CD4+ CD25+ Tregs and T helper 1 cells in …


S Han, P Liu, W Zhang, L Bu, M Shen, H Li, Y Fan, K … - Clinical Immunology, 2007 - Elsevier
Different subsets of T lymphocytes have different functions in atherosclerosis advancement. T
helper 1 cells and T regulatory 1 cells have been demonstrated to play opposite roles in rupture
of atherosclerotic lesion. However, the role of novel subset of T regulatory cells, known as ...
Cited by 8 - Related articles - All 3 versions

The role of neuropeptide Y and interaction with leptin in regulating feed intake and …

- reproduction-online.org
CR Barb, RR Kraeling, GB Rampacek, GJ Hausman - Reproduction, 2006 - Soc Reprod Fertility
Two experiments (EXP) were conducted in ovariectomized prepubertal gilts to test the hypothesis
that neuropeptide Y (NPY) stimulates appetite and modulates LH and GH secretion, and that
leptin modifies such acute effects of NPY on feeding behavior and LH and GH secretion. ...
Cited by 6 - Related articles - BL Direct - All 8 versions


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