- ►diabetesjournals.org UC Rogner, F Lepault, MC Gagnerault, D … - Diabetes, 2006 - Am Diabetes Assoc The genetic locus Idd6 confers susceptibility to the spontaneous development of
type 1 diabetes in the NOD mouse. Our studies on disease resistance of the
congenic mouse strain NOD.C3H 6.VIII showed that Idd6 influences T-cell ... Cited by 10 - Related articles - BL Direct - All 7 versions
ML Bergman, N Duarte, S Campino, M … - Diabetes, 2003 - Am Diabetes Assoc Type 1 diabetes in the nonobese diabetic (NOD) mouse is a multifactorial and
polygenic disease. The NOD-derived genetic factors that contribute to type 1
diabetes are named Idd (insulin-dependent diabetes) loci. To date, the ... Cited by 17 - Related articles - BL Direct - All 4 versions
ML Bergman, C Penha-Goncalves, K Lejon, … - Diabetologia, 2001 - Springer Non-obese diabetic (NOD) mice spontaneously de- velop autoimmune diabetes, a
disease that closely re- sembles Type I (insulin-dependent) diabetes mellitus in
humans [1]. This T-cell-dependent autoimmune disease is multifactorial and ... Cited by 12 - Related articles - BL Direct - All 3 versions
- ►oxfordjournals.org MS Hung, P Avner, UC Rogner - Human Molecular Genetics, 2006 - Oxford Univ Press The Idd6 murine type 1 diabetes locus has been shown to control diabetes by
regulating the protective activity of the peripheral immune system, as
demonstrated by diabetes transfer assays using splenocytes. The analysis of ... Cited by 8 - Related articles - BL Direct - All 6 versions
J Morin, C Boitard, D Vallois, P Avner, UC … - Mammalian Genome, 2006 - Springer Abstract In the nonobese diabetes mouse, the murine type 1 diabetes
susceptibility locus Idd20 interacts geneti- cally with the diabetes resistance
locus Idd19. Both Idds are located on distal mouse Chromosome 6, and ... Cited by 4 - Related articles - BL Direct - All 4 versions
CH Grimm*, UC Rogner, P Avner - Autoimmunity, 2003 - informahealthcare.com Three type 1 diabetes associated regions on distal mouse chromosome 6 have
recently been defined by the construction and analysis of a series of congenic
strains, carrying C3H/HeJ genomic material on a NOD/Lt genetic background. ... Cited by 6 - Related articles - BL Direct - All 6 versions
PA Lyons - Current opinion in immunology, 2002 - Elsevier The identification of the genetic variants that confer susceptibility to common
autoimmune diseases, such as type 1 diabetes (T1D) and systemic lupus
erythematosus (SLE), will provide significant insight into their ... Cited by 12 - Related articles - All 5 versions
SE Eckenrode, Q Ruan, P Yang, W Zheng, RA … - DIABETES-NEW YORK-, 2004 - Am Diabetes Assoc T ype 1 diabetes is a disease manifested when the insulin-producing pancreatic
-cells are de- stroyed by the immune system. Studies using the NOD mouse model,
which spontaneously devel- ops type 1 diabetes, have shown that both B- and ... Cited by 14 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org N Deruytter, O Boulard, HJ Garchon - Diabetes, 2004 - Am Diabetes Assoc Major histocompatibility complex (MHC) plays a largely predominant role in the
genetic predisposition to type 1 diabetes, in both humans and rodents. While
class II loci have long been recognized as essential, they do not fully ... Cited by 16 - Related articles - BL Direct - All 5 versions
- ►shouxi.net TC Brodnicki, AL Fletcher, DG Pellicci, SP … - Diabetes, 2005 - Am Diabetes Assoc Congenic mouse strains provide a unique resource for genetic dissection and
biological characterization of chromosomal regions associated with diabetes
progression in the nonobese diabetic (NOD) mouse. Idd11, a mouse diabetes ... Cited by 4 - Related articles - BL Direct - All 6 versions
