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Scholar Results 1 - 10 of about 101 related to Yang: Leucine regulation of glucokinase and ATP synthase sensitizes glucose-induced insulin.... (0.13 sec) 

Leucine regulation of glucokinase and ATP synthase sensitizes glucose-induced insulin …

- diabetesjournals.org
J Yang, RK Wong, MJ Park, J Wu, JR Cook, DA … - Diabetes, 2006 - Am Diabetes Assoc
We have recently shown that leucine culture upregulates ATP synthase β-subunit
(ATPSβ) and increases ATP level, cytosolic Ca 2+ , and glucose-induced insulin
secretion in rat islets. The aim is to test whether glucokinase expression ...
Cited by 11 - Related articles - BL Direct - All 6 versions

Why expression of some genes is disallowed in beta-cells


R Quintens, N Hendrickx, K Lemaire, F Schuit - Biochemical Society Transactions, 2008 - biochemsoctrans.org
A differentiated β-cell results not only from cell-specific gene expression,
but also from cell-selective repression of certain housekeeping genes. Indeed,
to prevent insulin toxicity, β-cells should handle insulin stores ...
Cited by 7 - Related articles - Cached - BL Direct - All 5 versions

Functional pancreatic beta-cell mass: Involvement in type 2 diabetes and therapeutic …


M Karaca, C Magnan, C Kargar - Diabetes and Metabolism, 2009 - Elsevier
In the adult, the pancreatic β-cell mass adapts insulin secretion to meet
long-term changes in insulin demand and, in particular, in the presence of
insulinresistance that is either physiological, such as pregnancy, or ...
Cited by 3 - Related articles - All 2 versions

[CITATION] In't Veld P, Mahler T, Schuit F, Van De Winkel M, et al.(1992) Differences in glucose …


R Kiekens - J Clin Invest
Cited by 4 - Related articles

Dynamics of insulin sensitivity,-cell function, and-cell mass during the development of …

- physiology.org
BG Topp, LL Atkinson, DT Finegood - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc
Both male Zucker Fatty (mZF) and lower-fat-fed female Zucker diabetic fatty
(LF-fZDF) rats are obese but remain normoglycemic. Male ZDF (mZDF) and
high-fat-fed female ZDF rats (HF-fZDF) are also obese but develop diabetes ...
Cited by 7 - Related articles - BL Direct - All 6 versions

Novel aspects of the molecular mechanisms controlling insulin secretion


L Eliasson, F Abdulkader, M Braun, J … - The Journal of Physiology, 2008 - Physiological Soc
Pancreatic β-cells secrete insulin by Ca 2+ -dependent exocytosis of secretory
granules. β-cell exocytosis involves SNARE (soluble NSF-attachment protein
receptor) proteins similar to those controlling neurotransmitter release ...
Cited by 8 - Related articles - All 6 versions

Leucine culture reveals that ATP synthase functions as a fuel sensor in pancreatic β-cells


J Yang, RK Wong, X Wang, J Moibi, MJ … - Journal of Biological Chemistry, 2004 - ASBMB
Our goal was to investigate whether leucine culture affects β-cell glucose
sensing. One-day culture of rat islets with 10 mm leucine had no effect on
glucose-induced insulin secretion. One-week leucine culture decreased the ...
Cited by 14 - Related articles - All 5 versions

[CITATION] In't Veld P, Pipeleers D (2006) Glibenclamide treatment recruits beta-cell subpopulation into …


Z Ling, Q Wang, G Stangé - Diabetes
Cited by 8 - Related articles

AMP-activated protein kinase and pancreatic/duodenal homeobox-1 involved in insulin …


X Zhang, N Sun, L Wang, H Guo, Q Guan, B … - Journal of cellular and molecular medicine, 2009 - interscience.wiley.com
The effect of leucine on glucose-stimulated insulin secretion (GSIS) in
pancreatic β-cells is quite controversial, and mechanism involved in the effect
has not been elucidated yet. Consequently, we aimed to investigate effect ...
Cited by 2 - Related articles - All 5 versions

Effects of supraphysiologic concentration glucose on pancreatic duodenal homeobox-1 …


欢迎参加全国医学论文写作研修班 - Chinese medical journal, 2007 - cmj.org
In normal pancreatic beta-cells, glucose is the main physiological regulator of
acute insulin secretion and biosynthesis, but supraphysiologic concentration
glucose has inhibitive effects on beta-cell secretion and sensitivity of ...
Cited by 2 - Related articles - Cached - BL Direct - All 7 versions


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