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Scholar Results 1 - 10 of about 101 related to Susztak: Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte.... (0.14 sec) 

Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte …

- diabetesjournals.org
K Susztak, AC Raff, M Schiffer, EP Böttinger - Diabetes, 2006 - Am Diabetes Assoc
Diabetic nephropathy is the most common cause of end-stage renal disease in the
US Recent studies demonstrate that loss of podocytes is an early feature of
diabetic nephropathy that predicts its progressive course. Cause and ...
Cited by 164 - Related articles - BL Direct - All 7 versions

A Novel Role for the Adaptor Molecule CD 2-associated Protein in Transforming Growth …


M Schiffer, P Mundel, AS Shaw, EP Böttinger - Journal of Biological Chemistry, 2004 - ASBMB
CD2-associated protein (CD2AP) is an adaptor molecule involved in T cell
receptor signaling and podocyte homeostasis. CD2AP-deficient mice develop
nephrotic syndrome and renal failure caused by glomerulosclerosis. Here we ...
Cited by 91 - Related articles - BL Direct - All 4 versions

Podocyte loss and progressive glomerular injury in type II diabetes.

- nih.gov [PDF] 
ME Pagtalunan, PL Miller, S Jumping-Eagle, … - Journal of Clinical Investigation, 1997 - Am Soc Clin Investig
Kidney biopsies from Pima Indians with type II diabetes were analyzed. Subjects
were classified clinically as having early diabetes (n = 10), microalbuminuria
(n = 17), normoalbuminuria, despite a duration of diabetes equal to that of ...
Cited by 356 - Related articles - BL Direct - All 8 versions

Glomerular cell number in normal subjects and in type 1 diabetic patients


MW Steffes, D Schmidt, R Mccrery, JM … - Kidney international, 2001 - nature.com
1 The International Diabetic Nephropathy Study Group (institution) members
include: (1) Keith Drummond (principal investigator), Christine Aebi, Mimi
Belmonte, Robert Gardiner, Paul Goodyear, Michael Kramer, Constantin ...
Cited by 141 - Related articles - BL Direct - All 4 versions

From the periphery of the glomerular capillary wall toward the center of disease

- diabetesjournals.org
G Wolf, S Chen, FN Ziyadeh - Diabetes, 2005 - Am Diabetes Assoc
Nephropathy is a major complication of diabetes. Alterations of mesangial cells
have traditionally been the focus of research in deciphering molecular
mechanisms of diabetic nephropathy. Injury of podocytes, if recognized at ...
Cited by 186 - Related articles - All 9 versions

Apoptosis in podocytes induced by TGF-beta and Smad7

- nih.gov [PDF] 
M Schiffer, M Bitzer, ISD Roberts, JB Kopp, P … - Journal of Clinical Investigation, 2001 - Am Soc Clin Investig
Primary and secondary forms of focal segmental glomerulosclerosis (FSGS) are
characterized by depletion of podocytes and constitute a central manifestation
of chronic progressive glomerular diseases. Here we report that podocytes ...
Cited by 272 - Related articles - BL Direct - All 4 versions

The podocyte's response to injury: role in proteinuria and glomerulosclerosis


SJ Shankland - Kidney international, 2006 - nature.com
The terminally differentiated podocyte, also called glomerular visceral
epithelial cell, are highly specialized cells. They function as a critical size
and charge barrier to prevent proteinuria. Podocytes are injured in ...
Cited by 132 - Related articles - BL Direct - All 5 versions

TGF-{beta} Concentration Specifies Differential Signaling Profiles of Growth Arrest/ …

- asnjournals.org
DT Wu, M Bitzer, W Ju, P Mundel, EP … - Journal of the American Society of Nephrology, 2005 - Am Soc Nephrol
Podocyte depletion occurs in most progressive glomerular diseases and is thought
to result from podocyte loss while the remaining podocytes are unable to
proliferate. The underlying mechanisms for podocyte growth arrest/ ...
Cited by 33 - Related articles - BL Direct - All 5 versions

High glucose promotes mesangial cell apoptosis by oxidant-dependent mechanism

- physiology.org [PDF] 
BPS Kang, S Frencher, V Reddy, A Kessler, A … - American Journal of Physiology- Renal Physiology, 2003 - Am Physiological Soc
47 articles, 22 of which you can access free at: This article cites
http://ajprenal.physiology.org/cgi/content/full/284/3/F455#BIBL ... 22 other
HighWire hosted articles, the first 5 are: This article has been cited by
Cited by 78 - Related articles - BL Direct - All 5 versions

Activation of a local tissue angiotensin system in podocytes by mechanical strain1


RV Durvasula, AT PETERMANN, K Hiromura, M … - Kidney international, 2004 - nature.com
Glomerular capillary hypertension, a common denominator in various forms of
progressive glomerular disease, results in mechanical distention of the
capillary tuft, and subsequent injury of the overlying podocyte layer. The ...
Cited by 141 - Related articles - All 4 versions


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