J Královičová, TR Gaunt, S Rodriguez, PJ Wood, INM … - Diabetes, 2006 - Am Diabetes Assoc Predisposition to type 1 diabetes and juvenile obesity is influenced by the susceptibility locus
IDDM2 that includes the insulin gene (INS). Although the risk conferred by IDDM2 has been attributed
to a minisatellite upstream of INS, intragenic variants have not been ruled out. We ... Related articles - All 2 versions
J Královicová, TR Gaunt, S Rodriguez, PJ Wood, INM … - Diabetes, 2006 - Am Diabetes Assoc Predisposition to type 1 diabetes and juvenile obesity is influenced by the susceptibility locus
IDDM2 that includes the insulin gene (INS). Although the risk conferred by IDDM2 has been attributed
to a minisatellite upstream of INS, intragenic variants have not been ruled out. We ... Cited by 31 - Related articles - BL Direct - All 5 versions
J Kre - 糖尿病学杂志, 2006 - journal.shouxi.net Predisposition to type 1 diabetes and juvenile obesity is influenced by the susceptibility locus
IDDM2 that includes the insulin gene (INS). Although the risk conferred by IDDM2 has been attributed
to a minisatellite upstream of INS, intragenic variants have not been ruled out. We ... Related articles - Cached
L Marchand, C Polychronakos - Diabetes, 2007 - Am Diabetes Assoc The association of type 1 diabetes with the insulin gene (IDDM2 locus) has been mapped to
a short haplotype encompassing two single nucleotide polymorphisms (SNPs) in perfect linkage
disequilibrium (r 2 = 1) with each other and with the two allele classes at the variable ... Cited by 5 - Related articles - BL Direct - All 5 versions
- ►pkuworld.org [PDF] T Bardelli, MA Donati, S Gasperini, F Ciani, F Belli, … - Molecular Genetics and …, 2002 - Elsevier Phenylalanine hydroxylase (PAH, EC 1.14.16.1) deficiency (MIM#261600) is an autosomal recessive
disorder of amino acid metabolism. The disease, characterized by hyperphenylalaninemia
(HPA), has been classified into three forms: classic phenylketonuria (PKU), variant PKU, ... Cited by 13 - Related articles - BL Direct - All 6 versions
DE Undlien, JP Berg - European Journal of Endocrinology, 2001 - eje.org Variable number of tandem repeat polymorphisms (VNTRs) are widely dispersed throughout
the genome. They consist of repeats of stereotypic DNA sequences and are generally found
in non-coding regions of DNA. For many VNTRs the number of repeat units display large ... Cited by 4 - Related articles - View as HTML - BL Direct - All 9 versions
GP DE NANCLARES, JR BILBAO, B … - … of diabetes II: …, 2003 - interscience.wiley.com Abstract: The VNTR region located at the 5'-end of the insulin gene on chromosome 11p15.5
is linked to susceptibility to type 1 diabetes mellitus (T1DM), and class I alleles have been associated
with increased risk of disease, whereas class III alleles are considered to be protective. ... Cited by 1 - Related articles - BL Direct - All 3 versions
- ►endojournals.org AH Minn, H Lan, ME Rabaglia, DM Harlan, BA … - Molecular …, 2005 - Endocrine Soc Type 2 diabetes occurs when pancreatic ß-cells become unable to compensate for the underlying
insulin resistance. Insulin secretion requires ß-cell insulin stores to be replenished by insulin
biosynthesis, which is mainly regulated at the translational level. Such translational ... Cited by 16 - Related articles - All 8 versions
- ►endojournals.org T Awata, E Kawasaki, H Ikegami, T Kobayashi, … - Journal of Clinical …, 2007 - Endocrine Soc Results: The frequency of the class I allele was 99.3% in patients and 96.7% in controls (P <
10 –5 ), and the class I/III or III/III genotype was found in 1.4% of patients and in 6.4% of controls
[odds ratio (OR) 0.20, P < 10 –5 ]. The class I subdivision revealed IC to increase ... Cited by 9 - Related articles - BL Direct - All 4 versions
