SL Gray, ED Nora, J Grosse, M Manieri, T Stoeger, G … - Diabetes, 2006 - Am Diabetes Assoc Peroxisome proliferator–activated receptor (PPAR)γ is a key transcription factor facilitating fat
deposition in adipose tissue through its proadipogenic and lipogenic actions. Human patients
with dominant-negative mutations in PPARγ display lipodystrophy and extreme insulin ... Cited by 17 - Related articles - BL Direct - All 4 versions
SL Gray, E Dalla Nora, J Grosse, M Manieri, T Stoeger … - 糖尿病学杂志, 2006 - journal.shouxi.net Peroxisome proliferator activated receptor (PPAR) is a key transcription factor facilitating fat deposition
in adipose tissue through its proadipogenic and lipogenic actions. Human patients with
dominant-negative mutations in PPAR display lipodystrophy and extreme insulin ... Related articles - Cached
- ►nih.gov M Agostini, E Schoenmakers, C Mitchell, I Szatmari, D … - Cell Metabolism, 2006 - Elsevier PPARγ is essential for adipogenesis and metabolic homeostasis. We describe mutations in the
DNA and ligand binding domains of human PPARγ in lipodystrophic, severe insulin
resistance. These receptor mutants lack DNA binding and transcriptional activity but can ... Cited by 42 - Related articles - All 11 versions
RA Hegele, E Ur, TP Ransom, H Cao - Clinical genetics, 2006 - ncbi.nlm.nih.gov 1: Clin Genet. 2006 Oct;70(4):360-2. A frameshift mutation in peroxisome-proliferator-
activated receptor-gamma in familial partial lipodystrophy subtype 3 (FPLD3; MIM
604367). Hegele RA, Ur E, Ransom TP, Cao H. Publication ... Cited by 11 - Related articles - All 3 versions
- ►nih.gov YS Tsai, HJ Kim, N Takahashi, HS Kim, JR … - Journal of Clinical …, 2004 - Am Soc Clin Investig Peroxisome proliferator–activated receptor γ (PPARγ), the molecular target of a class of insulin
sensitizers, regulates adipocyte differentiation and lipid metabolism. A dominant negative P467L
mutation in the ligand-binding domain of PPARγ in humans is associated with severe ... Cited by 81 - Related articles - BL Direct - All 10 versions
- ►oxfordjournals.org C Skurk, F Wittchen, L Suckau, H Witt, M … - European heart …, 2008 - Eur Soc Cardiology Methods and results: Oligonucleotide microarray analysis was performed on endomyocardial
biopsies (EMBs) from patients with early DCM (LVEDD 55 mm, LVEF 55%, n = 5) and control
subjects (LVEDD < 55 mm, LVEF > 60%, no cardiac pathology, n = 4). Adiponectin, an ... Cited by 5 - Related articles - BL Direct - All 6 versions
- ►endojournals.org K Al-Shali, H Cao, N Knoers, AR Hermus, CJ … - Journal of Clinical …, 2004 - Endocrine Soc Familial partial lipodystrophy (FPLD) results from coding sequence mutations either in
LMNA, encoding nuclear lamin A/C, or in PPARG, encoding peroxisome proliferator-activated
receptor (PPAR ). The LMNA form is called FPLD2 (MIM 151660), and the PPARG form is ... Cited by 34 - Related articles - BL Direct - All 6 versions
ZC Yan, ZM Zhu, CY Shen, ZG Zhao, YX Ni, J … - Zhonghua yi xue za …, 2004 - ncbi.nlm.nih.gov OBJECTIVE: To assess the relationship between PPAR gamma C161-T polymorphism and Carotid
Atherosclerosis in metabolic Syndrome (MS). METHODS: Polymerase chain reaction-restricted
fragments length polymorphism was used to study the distribution of the PPAR gamma ... Cited by 6 - Related articles - BL Direct
Y Xu, SR Farmer, BD Smith - Journal of Biological Chemistry, 2007 - ASBMB Recent reports demonstrate that peroxisome proliferator-ac- tivated receptor (PPAR ), a member
of the nuclear receptor superfamily, acts as a repressor of type I collagen synthesis. Our data
demonstrate that exogenously expressed PPAR down- regulates collagen expression in ... Cited by 7 - Related articles - All 4 versions
