MZ Vatamaniuk, RK Gupta, KA Lantz, NM Doliba, FM … - Diabetes, 2006 - Am Diabetes Assoc Foxa1 (formerly hepatic nuclear factor 3α) belongs to the family of Foxa genes that are expressed
in early development and takes part in the differentiation of endoderm-derived organs and the
regulation of glucose homeostasis. Foxa1 −/− pups are growth retarded and ... Cited by 12 - Related articles - BL Direct - All 6 versions
P White, L May… - Diabetes, 2008 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—Differentiation toward the endocrine lineage is dependent
on the transcription factor Neurogenin 3 (Neurog3, Ngn3). We utilize a Neurog3–enhanced green
fluorescent protein knock-in mouse model to isolate endocrine progenitor cells from ... Cited by 13 - Related articles - BL Direct - All 4 versions
- ►cell.com N Gao, P White, N Doliba, ML Golson, FM Matschinsky, … - Cell Metabolism, 2007 - Elsevier The winged-helix transcription factor Foxa2 regulates Pdx1 gene expression and fetal endocrine
pancreas development. We show here by inducible gene ablation that Foxa2 inactivation in mature
β cells induces hyperinsulinemic hypoglycemia in Foxa2 loxP/loxP ,Pdx1-CreERT2 adult ... Cited by 9 - Related articles - All 8 versions
- ►endocrinology-journals.org A Petri, J Ahnfelt-Ronne, KS Frederiksen, … - Journal of molecular …, 2006 - Soc Endocrinology To understand the molecular mechanisms regulating pancreatic endocrine development and
function, pancreatic gene expression was compared between Ngn3-deficient mice and littermate
controls on embryonic days 13 and 15. Microarray analysis identified 504 genes with ... Cited by 11 - Related articles - BL Direct - All 5 versions
Y Xu, S Wang, J Zhang, A Zhao, BZ Stanger, G Gu - Developmental biology, 2006 - Elsevier Endocrine differentiation in the early embryonic pancreas is regulated by Notch signaling. Activated
Notch signaling maintains pancreatic progenitor cells in an undifferentiated state, whereas suppression
of Notch leads to endocrine cell differentiation. Yet it is not known what mechanism is ... Cited by 11 - Related articles - All 4 versions
S Galetti, A Sarre, H Perreten, N Produit- … - Pflügers Archiv European …, 2009 - Springer Page 1. SIGNALING AND CELL PHYSIOLOGY Fatty acids do not activate UCP2 in pancreatic
beta cells: comparison with UCP1 Sandrine Galetti & Alexandre Sarre & Hélène Perreten &
Nathalie Produit-Zengaffinen & Patrick Muzzin & Françoise Assimacopoulos-Jeannet ... Related articles - All 2 versions
- ►endojournals.org [PDF] OT Hardy, HE Hohmeier, TC Becker, E … - Molecular …, 2006 - Endocrine Soc Page 1. Functional genomics of the pancreatic β-cell Hardy et al. 1 Functional genomics
of the β-cell: SCHAD regulates insulin secretion independent of K + currents Short
Title: Functional Genomics of the Beta-Cell Olga T. Hardy ... Related articles
FX Jiang, M Mehta, G Morahan - Pancreas, 2009 - pdfs.journals.lww.com MATERIALS AND METHODS Bioinformatics Algorithms for Quantification of Insulin Gene Transcripts
During ISL Development Currently, the contrast of expression (M) calculated from normalized
microarray data sets has been used to quantify dif- ferential gene transcript ... Related articles - All 4 versions
- ►biologists.org SB Nelson, AE Schaffer, M Sander - Development, 2007 - dev.biologists.org Despite much progress in identifying transcriptional regulators that control the specification of
the different pancreatic endocrine cell types, the spatiotemporal aspects of endocrine subtype
specification have remained largely elusive. Here, we address the mechanism by which ... Cited by 13 - Related articles - BL Direct - All 6 versions
D Ou, X Wang, DL Metzger, RFL James, P Pozzilli, A … - Human immunology, 2005 - Elsevier To better understand the cytokine death-signal transduction pathways in human β cells, we investigated
the inhibitory effects of Bcl-2 (protooncogene bcl-2) and X-linked inhibitor of apoptosis
(XIAP) on TRAIL (TNF-related apoptosis-inducing ligand)-induced human β-cell ... Cited by 12 - Related articles - All 3 versions
