J Janke, S Engeli, M Boschmann, F Adams, J … - Diabetes, 2006 - Am Diabetes Assoc Studies in mice suggest that adipocytes serve as glucose sensors and regulate
systemic glucose metabolism through release of serum retinol-binding protein 4
(RBP4). This model has not been validated in humans. RBP4 was highly ... Cited by 146 - Related articles - BL Direct - All 6 versions
- Free from Publisher YM Cho, BS Youn, H Lee, N Lee, SS Min, SH … - Diabetes Care, 2006 - Am Diabetes Assoc RESULTS—Plasma RBP4 concentrations were higher in the IGT and type 2 diabetic
groups than in the NGT group (median 18.9 [range 11.2–45.8], 20.9
[9.9–48.5], and 18.1 μg/ml [9.3–30.5], respectively). However, no ... Cited by 135 - Related articles - BL Direct - All 6 versions
- ►shouxi.net TE Graham, Q Yang, M Bluher, A Hammarstedt … - The New England journal of medicine, 2006 - nejm.highwire.org Background Insulin resistance has a causal role in type 2 diabetes. Serum levels
of retinol-binding protein 4 (RBP4), a protein secreted by adipocytes, are
increased in insulin-resistant states. Experiments in mice suggest that ... Cited by 369 - Related articles - BL Direct - All 8 versions
- ►daegu.ac.kr [PDF] TE Graham, CJ Wason, M Blüher, BB Kahn - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Levels of retinol binding protein (RBP4) are increased
in the serum of insulin-resistant human subjects even before overt diabetes
develops. RBP4 levels correlate with insulin resistance, BMI, WHR, ... Cited by 69 - Related articles - BL Direct - All 6 versions
C Erikstrup, OH Mortensen, BK Pedersen - The New England journal of medicine, 2006 - ncbi.nlm.nih.gov 1: N Engl J Med. 2006 Sep 28;355(13):1393-4; author reply 1394-5. Comment
on: N Engl J Med. 2006 Jun 15;354(24):2552-63. Retinol ... Cited by 40 - Related articles - All 2 versions
N Takashima, H Tomoike, N Iwai - N Engl J Med, 2006 - hartvig.org To the Editor: Graham et al. (June 15 issue)1 report that serum levels of
retinol-binding pro- tein 4 (RBP4) correlated with the magnitude of insulin
resistance in various subjects. However, RBP4 and plasma insulin levels ... Cited by 46 - Related articles - View as HTML - All 6 versions
- ►diabetesjournals.org N Stefan, AM Hennige, H Staiger, J Machann, … - Diabetes Care, 2007 - Am Diabetes Assoc RESULTS—Adjusted circulating RBP4 correlated negatively with insulin
sensitivity (clamp: r = −0.33, P = 0.005; OGTT: r = −0.36, P = 0.002) and
positively with parameters in the fasting state as insulin levels (r = ... Cited by 77 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org M Broch, J Vendrell, W Ricart, C Richart, JM … - Diabetes Care, 2007 - Am Diabetes Assoc RESULTS—Serum RBP4 concentration was nonsignificantly different among lean,
overweight, and obese subjects. Circulating RBP4 was not associated with age,
BMI, waist-to-hip ratio, or metabolic parameters, including insulin ... Cited by 45 - Related articles - BL Direct - All 11 versions
- ►endojournals.org S Gavi, LM Stuart, P Kelly, MM Melendez, DC … - Journal of Clinical Endocrinology & Metabolism, 2007 - Endocrine Soc Objectives: The primary objective of this study was to determine whether an
association between retinol-binding protein 4 (RBP4) and insulin resistance
exists in nonobese individuals without a family history or diagnosis of ... Cited by 58 - Related articles - BL Direct - All 5 versions
Q Yang, TE Graham, N Mody, F Preitner, OD … - Nature, 2005 - biotech.korea.ac.kr In obesity and type 2 diabetes, expression of the GLUT4 glucose transporter is
decreased selectively in adipocytes. Adipose-specific Glut4 (also known as
Slc2a4) knockout (adipose-Glut4 2 /2 ) mice show insulin resistance ... Cited by 585 - Related articles - View as HTML - All 13 versions