S Onengut-Gumuscu, JH Buckner, P … - Diabetes, 2006 - Am Diabetes Assoc A recent addition to the list of widely confirmed type 1 diabetes risk loci is
the PTPN22 gene encoding a lymphoid-specific phosphatase (Lyp). However,
evidence supporting a role for PTPN22 in type 1 diabetes derives entirely ... Cited by 28 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org C Chelala, S Duchatelet, ML Joffret, R … - Diabetes, 2007 - Am Diabetes Assoc The PTPN22 gene, encoding the lymphoid-specific protein tyrosine phosphatase, a
negative regulator in the T-cell activation and development, has been associated
with the susceptibility to several autoimmune diseases, including type 1 ... Cited by 18 - Related articles - BL Direct - All 4 versions
O Cinek, O Hradsky, G Ahmedov, A Slavcev, S … - Diabetes research and clinical practice, 2007 - Elsevier The PTPN22 is a negative regulator of the T cell response. Its +1858C > T
(R620W) polymorphism has been shown to associate with a risk for multiple
autoimmune diseases, including type 1 diabetes (T1D) and juvenile ... Cited by 11 - Related articles - All 9 versions
K Katarina, P Daniela, N Peter, R Marianna, C … - Experimental and Clinical Endocrinology and Diabetes, 2007 - thieme-connect.com Type 1 diabetes mellitus (T1DM) is one of the long-time studied autoimmune
disorders. The triggering of the autoimmune process has been ascribed to various
genes active in the regulation of the cytokine gene transcription including ... Cited by 9 - Related articles - BL Direct - All 4 versions
- ►endojournals.org JM Heward, OJ Brand, JC Barrett, JD Carr- … - Journal of Clinical Endocrinology & Metabolism, 2007 - Endocrine Soc Objective: Having previously reported significant association of the T allele of
rs2476601 in a Graves' disease (GD) cohort, we sought to determine whether novel
rheumatoid arthritis-associated SNPs were also contributing to ... Cited by 24 - Related articles - BL Direct - All 4 versions
B Salobir, M Šabovič, M Hojnik, S Čučnik, T … - Immunobiology, 2007 - Elsevier Antiphospholipid autoantibodies particularly antibodies against β2-glycoprotein
I (anti-β2GPI) are casually associated with thromboses in patients with
autoimmune diseases. However, their exact prevalence and role in the ... Cited by 4 - Related articles - All 4 versions
- ►pnas.org L Michou, S Lasbleiz, AC Rat, P Migliorini, A … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences The tyrosine phosphatase PTPN22 allele 1858T has been associated with rheumatoid
arthritis (RA) and other autoimmune diseases. RA is the most frequent of those
multifactorial diseases. The RA association was usually restricted to serum ... Cited by 32 - Related articles - BL Direct - All 11 versions
Y Park - Diabetes research and clinical practice, 2007 - Elsevier Progress has been made in investigating the genetic factors involved in type 1
diabetes (T1D) development for the past few years. While Linkage disequilibrium
(LD) mapping has been useful for both the confirmation and fine-mapping of ... Cited by 13 - Related articles - All 9 versions
M Ziegler, B Ziegler - Exp Clin Endocrinol, 1989 - grande.nal.usda.gov Record Detail. Return to previous page, Save: Title: Immunological disorders
of type 1 diabetes mellitus. Author: Ziegler, M : Ziegler ... Cited by 5 - Related articles - Cached - All 2 versions
M Varla-Leftherioti, T Keramitsoglou, M … - Tissue Antigens, 2007 - pt.wkhealth.com The aim of the study was to investigate whether human leukocyte antigen (HLA)
allele sharing between partners or the maternal killer immunoglobulin-like
receptor (KIR) repertoire is associated with recurrent spontaneous abortion ... Cited by 5 - Related articles - All 3 versions
