M Brissova, A Shostak, M Shiota, PO Wiebe, G … - Diabetes, 2006 - Am Diabetes Assoc To investigate molecular mechanisms controlling islet vascularization and revascularization
after transplantation, we examined pancreatic expression of three families of angiogenic factors
and their receptors in differentiating endocrine cells and adult islets. Using intravital lectin ... Cited by 40 - Related articles - BL Direct - All 6 versions
X Li, L Zhang, S Meshinchi, C Dias-Leme, D Raffin, JD … - Diabetes, 2006 - Am Diabetes Assoc Gene expression profiling of islets from pre-diabetic male Zucker diabetic fatty (ZDF) rats showed
increased expression of hypoxia-related genes, prompting investigation of the vascular integrity
of the islets. The islet microvasculature was increased approximately twofold in young ... Cited by 28 - Related articles - BL Direct - All 7 versions
Y Lai, D Schneider, A Kidszun, I Hauck- … - Transplantation, 2005 - journals.lww.com Transplantation. Wolters Kluwer Health | Lippincott Williams & Wilkins. All Issues. ... Cited by 47 - Related articles - All 4 versions
- ►cell.com G Nikolova, N Jabs, I Konstantinova, A Domogatskaya, … - Developmental cell, 2006 - Elsevier Endocrine pancreatic β cells require endothelial signals for their differentiation and function.
However, the molecular basis for such signals remains unknown. Here, we show that β cells,
in contrast to the exocrine pancreatic cells, do not form a basement membrane. Instead, ... Cited by 77 - Related articles - Library Search - All 18 versions
N Zhang, A Richter, J Suriawinata, S Harbaran, J … - Diabetes, 2004 - Am Diabetes Assoc Successful islet transplantation depends on the infusion of sufficiently large quantities of
islets, of which only ∼30% become stably engrafted. Rapid and adequate revascularization
of transplanted islets is important for islet survival and function. Delayed and insufficient ... Cited by 80 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org M Brissova, M Fowler, P Wiebe, A Shostak, M Shiota, A … - Diabetes, 2004 - Am Diabetes Assoc Pancreatic islet transplantation is an emerging therapy for type 1 diabetes. To survive and
function, transplanted islets must revascularize because islet isolation severs arterial and venous
connections; the current paradigm is that islet revascularization originates from the ... Cited by 69 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org D Nyqvist, M Köhler, H Wahlstedt, PO Berggren - Diabetes, 2005 - Am Diabetes Assoc Pancreatic islet transplantation has emerged as a therapy for type 1 diabetes and is today performed
using both freshly isolated and cultured islets. Islet blood vessels are disrupted during islet
isolation; therefore, proper revascularization of the transplanted islets is of great ... Cited by 43 - Related articles - BL Direct - All 6 versions
- ►cell.com E Lammert, G Gu, M McLaughlin, D Brown, R Brekken, … - Current Biology, 2003 - Elsevier Blood vessel endothelium has been recently shown to induce endocrine pancreatic development
[1]. Because pancreatic endocrine cells or islets express high levels of vascular endothelial growth
factors, VEGFs [2] and [3], we investigated the role of a particular VEGF, VEGF-A, on islet ... Cited by 118 - Related articles - All 19 versions
- ►endojournals.org M Johansson, G Mattsson, A Andersson, L Jansson, … - Endocrinology, 2006 - Endocrine Soc The growth of both tumors and nonneoplastic tissues may be influenced by signals from the vascular
endothelium. In the present investigation we show that purified proliferating endothelial cells
from pancreatic islets can stimulate ß-cell proliferation through secretion of hepatocyte ... Cited by 40 - Related articles - All 5 versions
- ►diabetesjournals.org G Mattsson, L Jansson, PO Carlsson - Diabetes, 2002 - Am Diabetes Assoc An adequate revascularization is crucial for islet survival and function after transplantation. Previous
studies have suggested that islet revascularization is concluded within 14 days after
transplantation. We investigated if the vascular density of transplanted islets and ... Cited by 83 - Related articles - BL Direct - All 7 versions
