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Scholar Results 1 - 10 of about 101 related to Pilegaard: PDH-E1α Dephosphorylation and Activation in Human Skeletal Muscle During Exercise. (0.12 sec) 

PDH-E1α Dephosphorylation and Activation in Human Skeletal Muscle During …

- diabetesjournals.org
H Pilegaard, JB Birk, M Sacchetti, M Mourtzakis, DG … - Diabetes, 2006 - Am Diabetes Assoc
To investigate pyruvate dehydrogenase (PDH)-E1α subunit phosphorylation and whether free
fatty acids (FFAs) regulate PDH activity, seven subjects completed two trials: saline (control)
and intralipid/heparin (intralipid). Each infusion trial consisted of a 4-h rest followed by a ...
Cited by 9 - Related articles - BL Direct - All 5 versions

PDH-E1 Dephosphorylation and Activation in Human Skeletal Muscle During …


H Pilegaard, JB Birk, M Sacchetti, M Mourtzakis, DG … - 糖尿病学杂志, 2006 - journal.shouxi.net
To investigate pyruvate dehydrogenase (PDH)-E1 subunit phosphorylation and whether free
fatty acids (FFAs) regulate PDH activity, seven subjects completed two trials: saline (control)
and intralipid/heparin (intralipid). Each infusion trial consisted of a 4-h rest followed by a ...
Related articles - Cached

Carbohydrate metabolism during prolonged exercise and recovery: interactions …

- physiology.org
M Mourtzakis, B Saltin, T Graham, H … - Journal of Applied …, 2006 - Am Physiological Soc
During prolonged exercise, carbohydrate oxidation may result from decreased pyruvate production
and increased fatty acid supply and ultimately lead to reduced pyruvate dehydrogenase
(PDH) activity. Pyruvate also interacts with the amino acids alanine, glutamine, and ...
Cited by 8 - Related articles - BL Direct - All 7 versions

Rapid upregulation of pyruvate dehydrogenase kinase activity in human skeletal …

- physiology.org
MJ Watt, GJF Heigenhauser, PJ LeBlanc, … - Journal of Applied …, 2004 - Am Physiological Soc
Prolonged moderate-intensity exercise is characterized by a progressive reduction in carbohydrate
oxidation and concomitant increase in fat oxidation. Pyruvate dehydrogenase (PDH) controls
the entry of pyruvate into oxidative pathways and is a rate-limiting enzyme for ...
Cited by 10 - Related articles - BL Direct - All 8 versions

Activation by exercise of human skeletal muscle pyruvate dehydrogenase in vivo.


G Ward, J Sutton, N Jones, C Toews - Clinical Science, 1982 - cs.portlandpress.com
1. The activity of pyruvate dehydrogenase in its active and inactive forms was measured in biopsy
samples obtained from the vastus lateralis muscle of healthy subjects before and after
exercise. 2. At rest, 40 +/- 4% (mean +/- SEM) of the enzyme was in the active form. 3. ...
Cited by 13 - Related articles - Cached - All 8 versions

Targeting cell death.


DJ Hausenloy, L Scorrano - Clinical pharmacology and therapeutics, 2007 - ncbi.nlm.nih.gov
Functional consequences of myocardial or cerebral infarction are the result of excessive cell
death. It is patent that preventing cell death is the therapeutic goal in any ischemia-reperfusion
setting. Mitochondria amplify apoptotic cascades and have emerged as crucial organelles ...
Cited by 8 - Related articles - All 2 versions

Mass spectrometry-based survey of age-associated protein carbonylation in rat …


L Prokai, LJ Yan, JL Vera-Serrano, SM … - Journal of Mass …, 2007 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ...
Cited by 8 - Related articles - BL Direct - All 3 versions

Energy metabolism, altered proteins, sirtuins and ageing: converging mechanisms …

- nih.gov
AR Hipkiss - Biogerontology, 2008 - Springer
Abstract The predominant molecular symptom of ageing is the accumulation of altered gene
products. Nutritional studies show that ageing in animals can be significantly influenced by dietary
restriction. Genet- ics has revealed that ageing may be controlled by changes in ...
Cited by 9 - Related articles - BL Direct - All 4 versions

Tricarboxylic acid cycle dysfunction as a cause of human diseases and tumor …

- physiology.org
JJ Briere, J Favier, AP Gimenez- … - American Journal of …, 2006 - Am Physiological Soc
THE TRICARBOXYLIC ACID (TCA) cycle, also known as the Krebs cycle, has long been considered
so crucial for the basal metabolism of cell that no significant and primary defect in any of its enzyme
components could be compatible with life (59, 63). On the basis of this assumption, ...
Cited by 10 - Related articles - BL Direct - All 3 versions

Elevated n-3 fatty acids in a high-fat diet attenuate the increase in PDH kinase …

- physiology.org
EA Turvey, GJF Heigenhauser, M Parolin … - Journal of Applied …, 2005 - Am Physiological Soc
We tested the hypothesis that a high-fat diet (75% fat; 5% carbohydrates; 20% protein), for which
15% of the fat content was substituted with n-3 fatty acids, would not exhibit the diet-induced
increase in pyruvate dehydrogenase kinase (PDK) activity, which is normally observed in ...
Cited by 9 - Related articles - All 6 versions


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