- ►diabetesjournals.org H Pilegaard, JB Birk, M Sacchetti, M Mourtzakis, DG … - Diabetes, 2006 - Am Diabetes Assoc To investigate pyruvate dehydrogenase (PDH)-E1α subunit phosphorylation and whether free
fatty acids (FFAs) regulate PDH activity, seven subjects completed two trials: saline (control)
and intralipid/heparin (intralipid). Each infusion trial consisted of a 4-h rest followed by a ... Cited by 9 - Related articles - BL Direct - All 5 versions
H Pilegaard, JB Birk, M Sacchetti, M Mourtzakis, DG … - 糖尿病学杂志, 2006 - journal.shouxi.net To investigate pyruvate dehydrogenase (PDH)-E1 subunit phosphorylation and whether free
fatty acids (FFAs) regulate PDH activity, seven subjects completed two trials: saline (control)
and intralipid/heparin (intralipid). Each infusion trial consisted of a 4-h rest followed by a ... Related articles - Cached
- ►physiology.org M Mourtzakis, B Saltin, T Graham, H … - Journal of Applied …, 2006 - Am Physiological Soc During prolonged exercise, carbohydrate oxidation may result from decreased pyruvate production
and increased fatty acid supply and ultimately lead to reduced pyruvate dehydrogenase
(PDH) activity. Pyruvate also interacts with the amino acids alanine, glutamine, and ... Cited by 8 - Related articles - BL Direct - All 7 versions
- ►physiology.org MJ Watt, GJF Heigenhauser, PJ LeBlanc, … - Journal of Applied …, 2004 - Am Physiological Soc Prolonged moderate-intensity exercise is characterized by a progressive reduction in carbohydrate
oxidation and concomitant increase in fat oxidation. Pyruvate dehydrogenase (PDH) controls
the entry of pyruvate into oxidative pathways and is a rate-limiting enzyme for ... Cited by 10 - Related articles - BL Direct - All 8 versions
G Ward, J Sutton, N Jones, C Toews - Clinical Science, 1982 - cs.portlandpress.com 1. The activity of pyruvate dehydrogenase in its active and inactive forms was measured in biopsy
samples obtained from the vastus lateralis muscle of healthy subjects before and after
exercise. 2. At rest, 40 +/- 4% (mean +/- SEM) of the enzyme was in the active form. 3. ... Cited by 13 - Related articles - Cached - All 8 versions
DJ Hausenloy, L Scorrano - Clinical pharmacology and therapeutics, 2007 - ncbi.nlm.nih.gov Functional consequences of myocardial or cerebral infarction are the result of excessive cell
death. It is patent that preventing cell death is the therapeutic goal in any ischemia-reperfusion
setting. Mitochondria amplify apoptotic cascades and have emerged as crucial organelles ... Cited by 8 - Related articles - All 2 versions
L Prokai, LJ Yan, JL Vera-Serrano, SM … - Journal of Mass …, 2007 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 8 - Related articles - BL Direct - All 3 versions
- ►nih.gov AR Hipkiss - Biogerontology, 2008 - Springer Abstract The predominant molecular symptom of ageing is the accumulation of altered gene
products. Nutritional studies show that ageing in animals can be significantly influenced by dietary
restriction. Genet- ics has revealed that ageing may be controlled by changes in ... Cited by 9 - Related articles - BL Direct - All 4 versions
- ►physiology.org JJ Briere, J Favier, AP Gimenez- … - American Journal of …, 2006 - Am Physiological Soc THE TRICARBOXYLIC ACID (TCA) cycle, also known as the Krebs cycle, has long been considered
so crucial for the basal metabolism of cell that no significant and primary defect in any of its enzyme
components could be compatible with life (59, 63). On the basis of this assumption, ... Cited by 10 - Related articles - BL Direct - All 3 versions
- ►physiology.org EA Turvey, GJF Heigenhauser, M Parolin … - Journal of Applied …, 2005 - Am Physiological Soc We tested the hypothesis that a high-fat diet (75% fat; 5% carbohydrates; 20% protein), for which
15% of the fat content was substituted with n-3 fatty acids, would not exhibit the diet-induced
increase in pyruvate dehydrogenase kinase (PDK) activity, which is normally observed in ... Cited by 9 - Related articles - All 6 versions