- ►shouxi.net AI Tarasov, HJ Welters, S Senkel, GU Ryffel, AT … - Diabetes, 2006 - Am Diabetes Assoc ATP-sensitive K + channels (K ATP channels) couple ß-cell metabolism to electrical activity and
thereby play an essential role in the control of insulin secretion. Gain-of-function mutations in
Kir6.2 (KCNJ11), the pore-forming ... Cited by 17 - Related articles - BL Direct - All 5 versions
- ►oxfordjournals.org P Proks, C Girard, FM Ashcroft - Human Molecular Genetics, 2005 - Oxford Univ Press Recent studies have shown that heterozygous mutations in KCNJ11, which encodes Kir6.2, the
pore-forming subunit of the ATP-sensitive potassium (K ATP ) channel, cause permanent neonatal
diabetes either alone (R201C, ... Cited by 33 - Related articles - BL Direct - All 6 versions
P Tammaro, P Proks, FM Ashcroft - The Journal of Physiology, 2006 - Physiological Soc ATP-sensitive K + (K ATP ) channels are hetero-octamers of inwardly rectifying K + channel (Kir6.2)
and sulphonylurea receptor subunits (SUR1 in pancreatic β-cells, SUR2A in heart). Heterozygous
gain-of-function mutations in ... Cited by 15 - Related articles - BL Direct - All 9 versions
- ►diabetesjournals.org K Shimomura, CAJ Girard, P Proks, J Nazim, JD Lippiat … - Diabetes, 2006 - Am Diabetes Assoc Heterozygous mutations in the human Kir6.2 gene (KCNJ11), the pore-forming subunit of the
ATP-sensitive K + channel (K ATP channel), are a common cause of neonatal diabetes. We identified a
novel KCNJ11 mutation, R50Q, that ... Cited by 21 - Related articles - BL Direct - All 6 versions
CAJ Girard, K Shimomura, P Proks, N Absalom, L … - Pflügers Archiv European …, 2006 - Springer Abstract ATP-sensitive potassium (K ATP ) channels, com- posed of pore-forming Kir6.2 and regulatory
sulphonylurea receptor (SUR) subunits, play an essential role in insulin secretion from pancreatic
beta cells. Binding of ATP to ... Cited by 20 - Related articles - BL Direct - All 4 versions
P Tammaro, C Girard, J Molnes, PR Njølstad, … - The EMBO …, 2005 - pubmedcentral.nih.gov ATP-sensitive K (K ATP ) channels, comprised of pore-forming Kir6.2 and regulatory SUR1 subunits,
play a critical role in regulating insulin secretion. Binding of ATP to Kir6.2 inhibits, whereas
interaction of MgATP with SUR1 ... Cited by 35 - Related articles - All 7 versions
H de Wet, MV Mikhailov, C Fotinou, M Dreger, … - FEBS …, 2007 - interscience.wiley.com The ATP-sensitive potassium (K ATP ) channel couples glucose metabolism to insulin secretion in
pancreatic β-cells. It comprises regulatory sulfonylurea receptor 1 and pore-forming Kir6.2
subunits. Binding and/or hydrolysis ... Cited by 9 - Related articles - BL Direct - All 4 versions
R Masia, D Enkvetchakul, CG Nichols - Journal of Molecular and Cellular …, 2005 - Elsevier ATP-sensitive potassium (K ATP ) channels are heterooctamers of an inward rectifier potassium
channel (Kir6) and a sulfonylurea receptor (SUR, a member of the ATP-binding cassette (ABC)
transporter family). In the ... Cited by 32 - Related articles - All 5 versions
P Proks, C Girard, S Haider, AL Gloyn, AT … - EMBO …, 2005 - pubmedcentral.nih.gov Inwardly rectifying potassium (Kir) channels control cell membrane K fluxes and electrical
signalling in diverse cell types. Heterozygous mutations in the human Kir6.2 gene (KCNJ11), the
pore-forming subunit of the ATP- ... Cited by 59 - Related articles - BL Direct - All 4 versions
[CITATION] Electrophysiology of the pancreatic B-cell and the mechanisms of inhibition of …
MJ Dunne, C Ammala, SG Straub, GWG Sharp - … En-docrine Pancreas and Regulation of …, 2001 Cited by 2 - Related articles
