- ►diabetesjournals.org M Mastorikou, M Mackness, B Mackness - Diabetes, 2006 - Am Diabetes Assoc HDL protects against atherosclerosis development. Defective functioning of HDL in type 2 diabetes
may be one cause of increased cardiovascular disease associated with type 2 diabetes. HDL
modulates LDL oxidation through the action of paraoxonase-1 (PON1), which is one of ... Cited by 15 - Related articles - BL Direct - All 5 versions
B Mackness, D Hine, P McElduff, M Mackness - Atherosclerosis, 2006 - Elsevier PON1 activity was different between the populations in the order: controls > type 1 diabetes >
type 2 diabetes > CHD with no diabetes (P < 0.001). CRP concentration also differed between
the populations in the order: controls < type 1 diabetes < type 2 diabetes < CHD with no ... Cited by 16 - Related articles - All 19 versions
M Mastorikou, B Mackness, Y Liu, M … - Diabetic Medicine, 2008 - pubmedcentral.nih.gov High-density lipoprotein (HDL) protects against atherosclerosis development. Defective functioning
of HDL in Type 2 diabetes may be one cause of increased cardiovascular disease associated
with Type 2 diabetes. HDL modulates low-density lipoprotein and cell membrane ... Cited by 3 - Related articles - All 6 versions
L Persegol, B Verges, M Foissac, P Gambert, L … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis: In healthy normolipidaemic and normoglycaemic control subjects,
HDL are able to reverse the inhibition of vasodilation that is induced by oxidised LDL. In type
2 diabetic patients, HDL are gly- cated and more triglyceride-rich than in control subjects. ... Cited by 7 - Related articles - BL Direct - All 3 versions
M Sampson, S Braschi, G Willis, S Astley - Clinical Science, 2005 - submit.clinsci.org The HDL (high-density lipoprotein)-associated enzyme PON (paraoxonase)-1 protects LDL
(low-density lipoprotein) from oxidative modification in vitro, although it is unknown if this
anti-atherogenic action occurs in vivo. In a cross-sectional study of 58 Type II diabetic ... Cited by 14 - Related articles - Cached - BL Direct - All 10 versions
- ►cutieswonderful.net [PDF] M Rosenblat, R Karry, M Aviram - Atherosclerosis, 2006 - Elsevier Serum HDL and LPDS fractions were isolated from control healthy subjects, diabetic and hypercholesterolemic
patients. PON1 activities and protein in HDL/LPDS, as well as its ability to protect against lipid
peroxidation and to stimulate HDL/LPDS-mediated macrophage cholesterol efflux were ... Cited by 28 - Related articles - All 73 versions
O Rozenberg, M Shiner, M Aviram, T Hayek - Free Radical Biology and …, 2008 - Elsevier Paraoxonase 1 (PON1) is a lipo-lactonase which is associated with HDL and possesses antioxidative
properties. Diabetes is characterized by increased oxidative stress and by decreased PON1
activity. We aimed to analyze whether oxidative status and PON1 levels in mouse sera ... Cited by 11 - Related articles - All 2 versions
MR Lakshman, CS Gottipati, SJ Narasimhan, J Munoz, … - Metabolism, 2006 - Elsevier Atherosclerotic risk is increased in diabetes partly because of increased plasma levels of the
oxidized low-density lipoprotein and homocysteine, 2 independent and important cardiovascular
disease (CVD) risk factors. Paraoxonase (PON) is a multifunctional antioxidant enzyme ... Cited by 14 - Related articles - All 15 versions
O ROZENBERG, M AVIRAM - Biochemical and biophysical research …, 2006 - cat.inist.fr HDL-associated paraoxonase 1(PON 1) undergoes inactivation under oxidative stress and is
preserved by dietary antioxidants. PON 1 cysteines can affect PON 1 enzymatic activities.
S-Glutathionylation, a redox regulatory mechanism characterized by the formation of a ... Cited by 15 - Related articles - All 3 versions
SAP Karabina, AN Lehner, E Frank, S Parthasarathy, N … - BBA-General Subjects, 2005 - Elsevier Human serum paraoxonase (PON1) has been implicated to play an important role in cardiovascular
disease and diabetes. Studies in the literature indicate that PON1 has two different enzyme
activities, ie, esterase and hydroperoxide reducing activities. The objective of this study ... Cited by 15 - Related articles - All 4 versions
