- ►diabetesjournals.org N Vionnet, D Tregouët, G Kazeem, I Gut, PH Groop, L … - Diabetes, 2006 - Am Diabetes Assoc Linkage studies have mapped loci for diabetic nephropathy and associated phenotypes on chromosome
3q. We studied 14 plausible candidate genes in the linkage region because of their potential
role in vascular complications. In a large-scale study of patients from Denmark, Finland, ... Cited by 33 - Related articles - BL Direct - All 6 versions
AM Osterholm, B He, J Pitkaniemi, L Albinsson, T Berg … - Kidney International, 2006 - nature.com Diabetic nephropathy (DN) is the primary cause of morbidity and mortality in patients with type
1 as well as type 2 diabetes, and accounts for 40% of end-stage renal disease in the Western
world. Familial clustering of DN suggests importance of genetic factors in the ... Cited by 33 - Related articles - BL Direct - All 5 versions
N Vionnet, D Tregouët, G Kazeem, I Gut, PH Groop, L … - DIABETES, 2006 - Am Diabetes Assoc Page 1. Original Article Analysis of 14 Candidate Genes for Diabetic Nephropathy
on Chromosome 3q in European Populations Strongest Evidence for Association
With a Variant in the Promoter Region of the Adiponectin Gene ... Related articles
SK Iyengar, HE Abboud, KAB Goddard, MF Saad, SG … - Diabetes, 2007 - Am Diabetes Assoc The Family Investigation of Nephropathy and Diabetes (FIND) was initiated to map genes underlying
susceptibility to diabetic nephropathy. A total of 11 centers participated under a single collection
protocol to recruit large numbers of diabetic sibling pairs concordant and discordant for ... Cited by 37 - Related articles - BL Direct - All 8 versions
KG Ewens, RA George, K Sharma, FN Ziyadeh, RS … - Diabetes, 2005 - Am Diabetes Assoc Several lines of evidence, including familial aggregation, suggest that allelic variation contributes
to risk of diabetic nephropathy. To assess the evidence for specific susceptibility genes, we used
the transmission/disequilibrium test (TDT) to analyze 115 candidate genes for linkage ... Cited by 34 - Related articles - BL Direct - All 5 versions
DW Bowden, CJ Colicigno, CD LANGEFELD, MM … - Kidney international, 2004 - nature.com DNA samples were collected from 206 type 2 diabetes (T2DM) and end-stage renal disease
(ESRD)/nephropathy-affected sib pairs from 166 African American families (355 affected
individuals). A genome scan was performed and data analyzed using nonparametric ... Cited by 85 - Related articles - BL Direct - All 4 versions
- ►asnjournals.org AJ McKnight, AP Maxwell, S Sawcer, A … - Journal of the American …, 2006 - Am Soc Nephrol In an effort to accelerate the identification of susceptibility genes in diabetic nephropathy, the
first genome-wide fluorescence-based DNA microsatellite (n = 6000) association screen was
performed, using pools of genomic DNA derived from Irish patients with (cases; n = 200) ... Cited by 19 - Related articles - BL Direct - All 5 versions
JD Center, AS Krolewski… - Kidney international, 2006 - mhp.koshigaya.saitama.jp Nominal P-values foe evidence for linkage in all relatives on 22 q, 5q and 7q were lower than
empirical, indicating that the nominal P-values may have slightly overstated the evidence for
linkage to these regions. In contrast, the support for linkage of logACR to chromosome 21 ... Cited by 42 - Related articles - BL Direct - All 4 versions
BI Freedman, NV Volkova, SG Satko, J Krisher, C … - Am J Nephrol, 2005 - content.karger.com Background: We determined the familial aggregation of end-stage renal disease (ESRD) in a
large, population-based sample of incident ESRD cases to assess the feasibility of developing
a targeted screening and prevention program directed at members of families at high risk ... Cited by 20 - Related articles - All 5 versions
- ►diabetesjournals.org A Shimazaki, Y Kawamura, A Kanazawa, A Sekine, S … - Diabetes, 2005 - Am Diabetes Assoc To search for a gene(s) conferring susceptibility to diabetic nephropathy (DN), we genotyped
over 80,000 gene-based single nucleotide polymorphisms (SNPs) in Japanese patients and
identified that the engulfment and cell motility 1 gene (ELMO1) was a likely candidate for ... Cited by 45 - Related articles - All 7 versions
