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Scholar Results 1 - 10 of about 101 related to Miettinen: Downregulation of EGF receptor signaling in pancreatic islets causes diabetes.... (0.07 sec) 

Downregulation of EGF receptor signaling in pancreatic islets causes diabetes due to …


PJ Miettinen, J Ustinov, P Ormio, R Gao, J … - Diabetes, 2006 - Am Diabetes Assoc
Epidermal growth factor receptor (EGF-R) signaling is essential for proper fetal
development and growth of pancreatic islets, and there is also evidence for its
involvement in β-cell signal transduction in the adult. To study the ...
Cited by 16 - Related articles - BL Direct - All 7 versions

Glibenclamide stimulates growth of human chondrocytes by IGF I dependent mechanisms.


E Heinze, U Vetter, RW Holl, RE Brenner - Experimental and clinical endocrinology & diabetes: …, 1995 - ncbi.nlm.nih.gov
In rats and men the sulfonylurea glibenclamide augmented skeletal growth.
However, with the design of the in vivo studies it was not possible to
distinguish whether the growth promoting effect of glibenclamide was ...
Cited by 6 - Related articles - BL Direct - All 2 versions

Transcriptional regulation of cyclin D2 by the PKA pathway and inducible cAMP early …

- biolreprod.org
LC Muñiz, G Yehia, E Mémin, PVAL Ratnakar … - Biology of reproduction, 2006 - Soc Study Reprod
Cyclin D2 (Ccnd2) is an essential gene for folliculogenesis, as null mutation in
mice impairs granulosa cell proliferation in response to FSH. Ccnd2 mRNA is
induced during the estrus cycle by FSH and is rapidly inhibited by LH. Yet, ...
Cited by 7 - Related articles - BL Direct - All 9 versions

Differential effects of p27 in regulation of β-cell mass during development, neonatal period, …

- diabetesjournals.org
L Rachdi, N Balcazar, L Elghazi, DJ Barker, I … - Diabetes, 2006 - Am Diabetes Assoc
The steps controlling entry and progression through G 1 are dependent on cell
type and context. Little is known about the cell cycle in β-cells, but recent
work from several laboratories has shown that cyclin-dependent kinase-4 ...
Cited by 12 - Related articles - BL Direct - All 5 versions

Combination therapy with epidermal growth factor and gastrin increases β-cell mass and …


WL Suarez-Pinzon, Y Yan, R Power, SJ Brand … - Diabetes, 2005 - Am Diabetes Assoc
Combination therapy with epidermal growth factor (EGF) and gastrin induces
β-cell regeneration in rodents with chemically induced diabetes. We
investigated whether EGF plus gastrin could correct hyperglycemia in NOD ...
Cited by 53 - Related articles - BL Direct - All 5 versions

Expression of ErbB receptors during pancreatic islet development and regrowth

- endocrinology-journals.org [PDF] 
MR Kritzik, T Krahl, A Good, D Gu, C Lai, H … - Journal of Endocrinology, 2000 - Soc Endocrinology
We have characterized expression of the ErbB receptor family and one of its
ligands, heregulin, in an effort to identify molecules associated with
pancreatic development and regeneration. In addition to studying expression ...
Cited by 29 - Related articles - BL Direct - All 3 versions

Tyrosine kinase receptors are crucial for normal-cell development and function


S Arnaud-Dabernat, N Sarvetnick - Expert Review of Endocrinology and Metabolism, 2007 - ingentaconnect.com
Signaling pathways play critical roles in most physiological and pathological
processes and convert an extracellular stimulus into a change of function in the
recipient cell. Intracellular messages originate from the activation of ...
Related articles - All 3 versions

Acute Suppression of Circulating sCD40L During Hyperglycemia and Euglycemic- …


SR Oliver, RL Flores, AM Pontello, JS Rosa, … - Journal of Investigative Medicine, 2008 - journals.lww.com
Skip Navigation Links Home > October 2008 - Volume 56 - Issue 7 > Acute
Suppression of Circulating sCD40L During Hyperglycemia... ... Oliver, Stacy R.;
Flores, Rebecca L.; Pontello, Andria M.; Rosa, Jaime S.; Zaldivar, Frank ...
Related articles - All 4 versions

$# x003b2; cell-specific deficiency of the stimulatory G protein $# x003b1;-subunit Gs $# …


T Xie, M Chen, QH Zhang, Z Ma, LS Weinstein - Proceedings of the National Academy of Sciences of …, 2007 - ukpmc.ac.uk
The G protein α-subunit G s α is required for hormone-stimulated cAMP
generation. In pancreatic β cells, G s α mediates the signaling of
glucagon-like peptide 1 and other incretin hormones, which are implicated ...
Related articles

Signaling Pathways Involved in Physiopathology of Pancreatic-Cells


S Dalle, S Costes, J Quoyer, G Bertrand, C … - Recent Patents on Endocrine, Metabolic &# 38; …, 2007 - ingentaconnect.com
Page 1. 180 Recent Patents on Endocrine, Metabolic & Immune Drug Discovery 2007,
1, 180-192 1872-2148/07 $100.00+.00 © 2007 Bentham Science Publishers Ltd. ...
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