- ►diabetesjournals.org BJ Clodfelder-Miller, AA Zmijewska, GVW … - Diabetes, 2006 - Am Diabetes Assoc Deficient signaling by insulin, as occurs in diabetes, is associated with
impaired brain function, and diabetes is associated with an increased prevalence
of Alzheimer's disease. One of the hallmark pathological characteristics of ... Cited by 14 - Related articles - BL Direct - All 6 versions
AM Moloney, RJ Griffin, S Timmons, RO'Connor, R … - Neurobiology of Aging, 2008 - Elsevier Insulin like growth factor-1 receptor (IGF-1R) and insulin receptor (IR)
signalling control vital growth, survival and metabolic functions in the brain.
Here we describe specific and significant alterations in IGF-1R, IR, and ... Cited by 15 - Related articles - All 2 versions
- ►jbc.org D Cao, H Lu, TL Lewis, L Li - Journal of Biological Chemistry, 2007 - ASBMB Compelling evidence indicates that excess consumption of sugar-sweetened
beverages plays an important role in the epidemic of obesity, a major risk
factor for type 2 diabetes mellitus. Type 2 diabetes mellitus has been ... Cited by 15 - Related articles - All 5 versions
E Grünblatt, M Salkovic-Petrisic, J Osmanovic … - J Neurochem, 2007 - alzheimer-forschung.de Abstract The intracerebroventricular (icv) application of streptozotocin (STZ)
in low dosage was used in 3-month-old rats to explore brain insulin system
dysfunction. Three months following STZ icv treatment, the expression of ... Cited by 26 - Related articles - View as HTML - BL Direct - All 8 versions
- ►diabetesjournals.org S Freude, L Plum, J Schnitker, U Leeser, M … - Diabetes, 2005 - Am Diabetes Assoc Cerebral insulin receptors play an important role in regulation of energy
homeostasis and development of neurodegeneration. Accordingly, type 2 diabetes
characterized by insulin resistance is associated with an increased risk of ... Cited by 26 - Related articles - BL Direct - All 6 versions
- ►whiterose.ac.uk [PDF] ERLC Vardy, PJ Rice, PCW Bowie, JD Holmes … - Journal of Alzheimer's Disease, 2007 - IOS Press Emma RLC Vardya, Penny J. Ricea, Peter CW Bowieb, John D. Holmesc, Peter J.
Granta and Nigel M. Hooperd,∗ aAcademic Unit of Molecular Vascular Medicine,
Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, ... Cited by 7 - Related articles - BL Direct - All 4 versions
V Meske, F Albert, TG Ohm - Journal of Biological Chemistry, 2008 - ASBMB Tau is an important microtubule-stabilizing protein in neurons. In its
hyperphosphorylated form, Tau protein loses its ability to bind to microtubules
and then accumulates and is part of pathological lesions characterizing ... Cited by 8 - Related articles - All 5 versions
- ►cjb.net E Planel, Y Tatebayashi, T Miyasaka, L Liu, … - Journal of Neuroscience, 2007 - neuro.cjb.net Hyperphosphorylated tau is the major component of paired helical filaments in
neurofibrillary tangles found in Alzheimer's disease (AD) brains, and tau
hyperphosphorylation is thought to be a critical event in the pathogenesis ... Cited by 21 - Related articles - All 4 versions
CC Huang, JL You, CC Lee, KS Hsu - Molecular and Cellular Neuroscience, 2003 - Elsevier The mechanisms of induction and the site of expression of long-term depression
(LTD) at the hippocampal mossy fiber-CA3 synapses are not clear. Here, we show
that a brief bath application of insulin induces a novel form of mossy ... Cited by 10 - Related articles - All 4 versions
A Sengupta, I Grundke-Iqbal, K Iqbal - Neurochemical research, 2006 - Springer Abstract Microtubule associated protein tau is abnor- mally hyperphosphorylated
in Alzheimer disease (AD) brain. To investigate the role of protein kinases
involved in this lesion, metabolically active slices made from brains of ... Cited by 10 - Related articles - BL Direct - All 5 versions
